Catalytic asymmetric umpolung reaction of imines to synthesize isoindolinones and tetrahydroisoquinolines
Ze-Dong Mou, Xia Zhang, Dawen Niu
Green Synthesis and Catalysis · 2021
doi:10.1016/j.gresc.2021.01.001 (opens in a new tab)
We email you when a new notice or a question about this paper appears.
Abstract
Isoindolinone- and tetrahydroisoquinoline-based cyclic scaffolds comprise the key, structural feature of a wide range of biologically active molecules. Here we report an, approach for the synthesis of chiral isoindolinones and tetrahydroisoquinolines based, on the umpolung allylation of imines. The products contain a free N–H group, which is, primed for further derivatization.
Abstract licence: CC BY-NC-ND
Reads
Read by people on this page
None yet.
Checked or read by AI through naulon
None yet.
A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.
Are you an author?
Is this your paper?
Claim it to add your note and be paid when agents cite it. Free.