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Prognostic gene signature profiles of hepatitis C-related early-stage liver cirrhosis

Anu Venkatesh, Xiaochen Sun, Yujin Hoshida

Genomics Data · 2014

doi:10.1016/j.gdata.2014.10.007 (opens in a new tab)

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Abstract

The rate of hepatitis C virus (HCV) related liver cirrhosis and subsequent cancer development is increasing and raising the risk of related mortality and morbidity. To address this issue, we aimed to develop a prognostic index that can be used to stratify patients for risk of disease progression. This index was developed in part by using a gene signature test implemented in a clinically applicable digital transcript counting platform (NanoString nCounter system). A cohort of 145 U.S. patients with HCV-related early-stage cirrhosis was analyzed by using the assay. This dataset (GEO accession number GPL17230) provides information of expression levels of the prognostic genes in the cohort.

Abstract licence: CC BY-NC-ND

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