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Kidney Thrombotic Microangiopathy After COVID-19 Associated With C3 Gene Mutation

Olivier Mat, Lidia Ghisdal, Annick Massart and 6 more

Kidney International Reports · 2021

doi:10.1016/j.ekir.2021.03.897 (opens in a new tab)

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Abstract

Acute kidney injury (AKI) is not uncommon in patients with coronavirus disease 2019 (COVID-19), but thrombotic microangiopathy (TMA) linked to COVID-19 has been exceptionally reported in another patient.1 However, COVID-19–infected patients can develop proteinuria (44%), hematuria (27%), or AKI (5.1%).2 We report a case of atypical hemolytic uremic syndrome (aHUS) associated with COVID-19. This case highlights the importance of a rapid diagnosis, a good medical history, and a genetic analysis to optimize the management of this rare disease.

Abstract licence: CC BY-NC-ND

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