Culture-free proof of Mycobacterium tuberculosis - a new assay for viable bacteria
Jan Heyckendorf, Stephen H. Gillespie, Morten Ruhwald
EBioMedicine · 2020
doi:10.1016/j.ebiom.2020.103117 (opens in a new tab)
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Abstract
The current gold standard for the diagnosis of viable Mycobacterium tuberculosis bacteria is culture [1]. Mycobacterial culture is performed in laboratories worldwide providing absolute confirmation of the presence of the pathogen. The culture of mycobacteria has several disadvantages: it requires a high level of technological facilities, and is relatively costly. In addition, time to detection takes up to 2 months, significantly delaying the diagnosis of active tuberculosis in a large number of patients.
Abstract licence: CC BY-NC
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