Genetic Susceptibility to Oxidative Stress and Cardiovascular Disease

Cardiovascular disease continues to be the leading cause of death in patients with Type-2 Diabetes Mellitus (T2D). Aggressive use of HMG-CoA Reductase Inhibitors (statins) and blood pressure lowering agents are showing signs of success as rates of coronary heart disease are on the decline (Ali et al., 2013); however, a substantial amount of residual risk remains suggesting that additional prevention strategies are needed particularly in light of recent increases in the prevalence of T2D (Gregg et al., 2007).

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