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2015: The Year of Anti-PD-1/PD-L1s Against Melanoma and Beyond

Paolo A. Ascierto, Francesco M. Marincola

EBioMedicine · 2015

doi:10.1016/j.ebiom.2015.01.011 (opens in a new tab)

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Abstract

The history of clinical oncology has witnessed several revolutionary therapeutic advances that have significantly improved cancer care. These have included the introduction of cisplatin in the 1970s for testicular and ovarian cancers, the taxanes in the 1990s for breast and other solid tumors, targeted therapy with anti-HER2 for breast cancer and c-Kit inhibitors for chronic myeloid leukemia and other cancers at the start of this millennium. Each of these treatments has revolutionized outcomes for patients with various types of cancer.

Abstract licence: CC BY-NC

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