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Adult worm exclusion and histological data of dogs repeatedly infected with the cestode Echinococcus multilocularis

Hirokazu Kouguchi, Hidefumi Furuoka, Takao Irie and 6 more

Data in Brief · 2020

doi:10.1016/j.dib.2020.105353 (opens in a new tab)

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Abstract

The data presented in this article are related to a previously published research article titled “The timing of worm exclusion in dogs repeatedly infected with the cestode Echinococcus multilocularis” (2016) [1]. This data describe a comparison of worm exclusion in the early stage of infection (1 day and 6 days post-infection) between dogs infected for the first time (control group) and dogs repeatedly infected with the parasite 4 times (repeated infection groups). We observed that 6 days post reinfection, the number of adult worms in repeated-infection groups decreased by 88.7% compared with the control group. Histological analysis comparison of the small intestinal mucosa from healthy, first infected, and repeatedly infected dogs are also reported. We observed no clear pathological abnormality, except the shortening of microvillus in reinfected dogs. However, eosinophil accumulation and eosinophilic ulcers were observed in some reinfected dogs. This data could be useful as preliminary data to develop a final host vaccine for this parasite. Keywords: Echinococcus multilocularis, Vaccine, Repeated infection, Dog, Final host, Mucosal immunity, Histological analysis

Abstract licence: CC BY-NC

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