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Data supporting the role of Fyn in initiating myelination in the peripheral nervous system

Yuki Miyamoto, Moe Tamano, Tomohiro Torii and 5 more

Data in Brief · 2016

doi:10.1016/j.dib.2016.03.096 (opens in a new tab)

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Abstract

Transgenic mice, which express active Fyn tyrosine kinase under the control of a glial fibrillary acidic protein promoter, have been produced. This promoter induces protein expression in the initiation stage of myelination in the peripheral nervous system (PNS) “Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development (Yamauchi et al., 2015 [1])”. Herein we provide the data regarding myelination-related protein markers and myelin ultrastructure in transgenic mice. Keywords: Fyn, Myelination, Peripheral nervous system, Myelin marker protein, Signaling

Abstract licence: CC BY-NC

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