Loss of Muscle MTCH2 Increases Whole-Body Energy Utilization and Protects from Diet-Induced Obesity

(Cell Reports 14, 1602–1610; February 23, 2016) In the originally published version of this article, there was a mistake in Figure S1B: the two fields originally presented were adjacent views of the same gastrocnemius muscle sample. At the time of image acquisition, the images presented in the paper were mislabeled. To correct for this mistake, the authors returned to the original slides (prepared at the original time of collection; prior to publication) and chose two different experiments containing three mice from each genotype (a total of six mice/slides) and acquired images of each. The authors have used these pictures to prepare a corrected version of Figure S1, which has now been corrected online and appears below. The authors regret this error.Figure S1Characteristics of Mice Deficient for Muscle MTCH2 (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT) Loss of Muscle MTCH2 Increases Whole-Body Energy Utilization and Protects from Diet-Induced ObesityBuzaglo-Azriel et al.Cell ReportsFebruary 11, 2016In BriefThe MTCH2 locus is associated with increased obesity in humans. Buzaglo-Azriel et al. show that muscle MTCH2 deficiency in mice provides protection from a high-fat diet and that this protection is most likely due to increased muscle metabolism, leading to elevated whole-body energy demand and heat production. Full-Text PDF Open Access

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