RNA Seeds Higher-Order Assembly of FUS Protein

Cited by papers we hold 16

• Liquid-Liquid Phase Separation of TDP-43 and FUS in Physiology and Pathology of Neurodegenerative Diseases · 2022
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• On the role of phase separation in the biogenesis of membraneless compartments · 2022
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• Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription · 2021
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• In vivo reconstitution finds multivalent RNA–RNA interactions as drivers of mesh-like condensates · 2021
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• SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs · 2020
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• Molecular Crowding Tunes Material States of Ribonucleoprotein Condensates · 2019
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• A unified mechanism for LLPS of ALS/FTLD-causing FUS as well as its modulation by ATP and oligonucleic acids · 2019
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• RNA is a critical element for the sizing and the composition of phase-separated RNA–protein condensates · 2019
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• Phase separation in biology; functional organization of a higher order · 2016
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• ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43 · 2016
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• ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function · 2015
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• Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose) · 2015
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• Nucleic acid-binding specificity of human FUS protein · 2015
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• Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules · 2014
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• 3D imaging of Sox2 enhancer clusters in embryonic stem cells · 2014
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• Functions of FUS/TLS From DNA Repair to Stress Response: Implications for ALS · 2014
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