Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic

Cited by papers we hold 22

• C9ORF72: What It Is, What It Does, and Why It Matters · 2021
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• The role of hnRNPs in frontotemporal dementia and amyotrophic lateral sclerosis · 2020
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• Repeat‐associated non‐AUG translation in C9orf72‐ALS/FTD is driven by neuronal excitation and stress · 2019
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• RNA toxicity in non‐coding repeat expansion disorders · 2019
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• Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly · 2019
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• Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy · 2019
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• RNA Dysregulation in Amyotrophic Lateral Sclerosis · 2019
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• ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now? · 2019
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• Modelling amyotrophic lateral sclerosis: progress and possibilities · 2017
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• SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits · 2017
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• RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response · 2017
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• TBK1: a new player in ALS linking autophagy and neuroinflammation · 2017
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• RNA metabolism in neurodegenerative disease · 2017
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• The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains · 2016
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• C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production and glomerulonephropathy in mice · 2016
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• The hnRNP family: insights into their role in health and disease · 2016
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• Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing · 2015
  Corrected
• TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets · 2015
  Corrected
• Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy · 2015
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• Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions · 2014
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and 2 more

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