Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity

Cited by papers we hold 21

• Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders · 2023
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• Molecular mechanisms of mitochondrial DNA release and activation of the cGAS-STING pathway · 2023
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• The cGAS-STING Pathway in Bacterial Infection and Bacterial Immunity · 2022
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• Mitochondria and cell death-associated inflammation · 2022
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• Clathrin-associated AP-1 controls termination of STING signalling · 2022
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• cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila · 2021
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• Molecular Mechanisms of mtDNA-Mediated Inflammation · 2021
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• Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response · 2020
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• Interferon-independent STING signaling promotes resistance to HSV-1 in vivo · 2020
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• Mitochondrial DNA in inflammation and immunity · 2020
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• Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death · 2019
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• ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response · 2018
  Corrected
• DNA-induced liquid phase condensation of cGAS activates innate immune signaling · 2018
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• TRIM56-mediated monoubiquitination of cGAS for cytosolic DNA sensing · 2018
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• SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing · 2017
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• The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response · 2017
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• IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP · 2017
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• DNA sensor cGAS-mediated immune recognition · 2016
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• Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response · 2016
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• Ribosome•RelA structures reveal the mechanism of stringent response activation · 2016
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and 1 more

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