Immune thrombocytopenia associated with pleural and pericardial tuberculosis: case report
João Madaleno, António Fernandes, Joana Cochicho and 2 more
Revista Brasileira de Hematologia e Hemoterapia · 2016
doi:10.1016/j.bjhh.2016.02.002 (opens in a new tab)
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Abstract
Tuberculosis (TB) remains a major global health problem, responsible for the ill health of millions of people each year, and ranks as the second leading cause of death from an infectious disease worldwide.1 A variety of clinical manifestations are associated directly or indirectly with TB. Among them, hematological abnormalities can be found in both the pulmonary and extrapulmonary forms of the disease, and though a myriad of hematological disorders have been described, anemia, leukocytosis, and pancytopenia are the most frequently cited.2 Thrombocytopenia is usually associated with disseminated or miliary TB and when it occurs, it does so most commonly via non-immunologic means, typically manifesting in the context of pancytopenia that develops secondary to granulomatous infiltration of the bone marrow.3 A causal association between TB and immune thrombocytopenia (ITP) is extraordinarily rare and, to our knowledge,
Abstract licence: CC BY-NC-ND
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