Remission of refractory Crohn's disease after autologous hematopoietic stem cell transplantation
Milton Artur Ruiz, Roberto Luiz Kaiser Junior, Mikaell Alexandre Gouvêa Faria and 1 more
Revista Brasileira de Hematologia e Hemoterapia · 2015
doi:10.1016/j.bjhh.2015.01.002 (opens in a new tab)
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Abstract
The etiology of CD is unknown, but several proven riskfactors exist such as family history, smoking, oral contra-ceptives, diet and ethnicity. The combination of risk factors,and aberrant autoimmune response in the intestinal mucosawith endothelial dysfunction lead to digestive tract malfunc-tioning. Disease manifestations are heterogeneous but mostpatients present with abdominal pain, diarrhea sometimeswith blood, weight loss, fever and perianal lesions. Up to 30%of
Abstract licence: CC BY-NC-ND
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