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COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions

Larissa Daniele Bobermin, André Quincozes-Santos

Brain, Behavior, & Immunity - Health · 2021

doi:10.1016/j.bbih.2021.100257 (opens in a new tab)

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Abstract

Although COVID-19 affects the respiratory system, extrapulmonary manifestations frequently occur, including encephalopathy and liver damage. Here, we want to call attention to a possible connection between liver and brain dysfunctions, in which ammonia can play a role targeting astrocytes. Importantly, astrocyte dysfunction can produce future and/or long-term neurological consequences.

Abstract licence: CC BY-NC

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