Degradation of proteins by PROTACs and other strategies

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     Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation · 2017

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     Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome System · 2018

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248. 248.

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249. 249.

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250. 250.

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251. 251.

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252. 252.

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253. 253.

     This reference’s wording can’t be shown under the paper’s licence.

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254. 254.
     Microglia in Alzheimer's Disease: Risk Factors and Inflammation · 2018

     No notice
255. 255.

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256. 256.

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257. 257.

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258. 258.

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259. 259.

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260. 260.
     The PROTAC technology in drug development · 2019

     No notice
261. 261.

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262. 262.

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263. 263.
     Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase · 2019

     No notice
264. 264.
     Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs · 2019

     No notice
265. 265.

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266. 266.

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270. 270.

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271. 271.
     Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models · 2019

     No notice
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273. 273.

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275. 275.

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285. 285.

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Cited by papers we hold 8

• New-generation advanced PROTACs as potential therapeutic agents in cancer therapy · 2024
  No notice
• Role of p53 in breast cancer progression: An insight into p53 targeted therapy · 2023
  No notice
• Targeted protein degradation: mechanisms, strategies and application · 2022
  No notice
• An overview of PROTACs: a promising drug discovery paradigm · 2022
  No notice
• Amide-to-Ester Substitution as a Strategy for Optimizing PROTAC Permeability and Cellular Activity · 2021
  No notice
• Small molecules in targeted cancer therapy: advances, challenges, and future perspectives · 2021
  No notice
• Understanding the Metabolism of Proteolysis Targeting Chimeras (PROTACs): The Next Step toward Pharmaceutical Applications · 2020
  No notice
• The peptide PROTAC modality: a novel strategy for targeted protein ubiquitination · 2020
  No notice

Reads

A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.