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Progress in the biological function of alpha-enolase

Hong Ji, Jianfa Wang, Jingru Guo and 8 more

Animal Nutrition · 2016

doi:10.1016/j.aninu.2016.02.005 (opens in a new tab)

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Abstract

Alpha-enolase (ENO1), also known as 2-phospho-D-glycerate hydrolase, is a metalloenzyme that catalyzes the conversion of 2-phosphoglyceric acid to phosphoenolpyruvic acid in the glycolytic pathway. It is a multifunctional glycolytic enzyme involved in cellular stress, bacterial and fungal infections, autoantigen activities, the occurrence and metastasis of cancer, parasitic infections, and the growth, development and reproduction of organisms. This article mainly reviews the basic characteristics and biological functions of ENO1.

Abstract licence: CC BY-NC-ND

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