Corneal ulceration and episcleritis associated with Wiskott–Aldrich syndrome

Purpose: To present anterior segment ophthalmic manifestations of Wiskott–Aldrich syndrome (WAS), a rare X-linked primary immune-deficiency. Observations: A 15-year old male with WAS presented with multiple corneal ulcers of the left eye. Once resolved, this was followed by separate episodes of episcleritis in the left eye and corneal infiltrates of the right eye. Successful treatment included topical antibiotics and anti-inflammatories. Conclusions: Ocular manifestations of WAS, due to secondary infection and inflammation, may be severe. This case report emphasizes the importance of prompt ophthalmic evaluation and treatment of these patients.

Abstract licence: CC BY-NC

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