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Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

Jun-Li Yang, Lei-Lei Liu, Yan-Ping Shi

Natural Products and Bioprospecting · 2019

doi:10.1007/s13659-019-0199-9 (opens in a new tab)

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Abstract

Abstract The flowers of Chrysanthemum indicum, i.e. Ye-ju-hua recorded in the Chinese Pharmacopoeia, has been widely used in China as an important heat-clearing and detoxifying herb for the treatment of inflammation, headache, and vertigo. A phytochemical investigation of this herb has led to the isolation of two new eudesmane sesquiterpenoids, 7-epi-eudesm-4(15),11(13)-diene-1β,3β-diol (1) and 7-epi-1β-hydroxy-β-eudesmol (2). The molecular structures of these new sesquiterpenoids were established based on the comprehensive spectroscopic analyses, including NMR, MS, and IR, and comparing with the literatures. Graphical Abstract

Abstract licence: CC BY

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