H9N2 influenza virus in China: a cause of concern

Abstract

The recent human infection with avian influenza virus revealed that H9N2 influenza virus is the gene donor for H7N9 and H10N8 viruses infecting humans. The crucial role of H9N2 viruses at the animal-human interface might be due to the wide host range, adaptation in both poultry and mammalian, and extensive gene reassortment. As the most prevalent subtype of influenza viruses in chickens in China, H9N2 also causes a great economic loss for the poultry industry, even under the long-term vaccination programs. The history, epidemiology, biological characteristics, and molecular determinants of H9N2 influenza virus are reviewed in this paper. The contribution of H9N2 genes, especially RNP genes, to the infection of humans needs to be investigated in the future.

Cited by papers we hold 7

• Emergence, Evolution, and Biological Characteristics of H10N4 and H10N8 Avian Influenza Viruses in Migratory Wild Birds Detected in Eastern China in 2020 · 2022
  Not checked
• Dominant subtype switch in avian influenza viruses during 2016–2019 in China · 2020
  No notice
• Identification of Amino Acid Residues Responsible for Inhibition of Host Gene Expression by Influenza A H9N2 NS1 Targeting of CPSF30 · 2018
  Not checked
• Replication of H9 influenza viruses in the human ex vivo respiratory tract, and the influence of neuraminidase on virus release · 2017
  Not checked
• Current situation of H9N2 subtype avian influenza in China · 2017
  No notice
• Phylogenetic analysis and pathogenicity assessment of two strains of avian influenza virus subtype H9N2 isolated from migratory birds: High homology of internal genes with human H10N8 virus · 2016
  Not checked
• Replication Capacity of Avian Influenza A(H9N2) Virus in Pet Birds and Mammals, Bangladesh · 2015
  Not checked

Reads

A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.