Consensus guidelines for the use and interpretation of angiogenesis assays

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    Hida K, Hida Y, Amin DN, Flint AF, Panigrahy D, Morton CC, Klagsbrun M. Tumor-associated endothelial cells with cytogenetic abnormalities. Cancer Res. 2004;64(22):8249-8255.

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69. 69.

    Stacker SA, Halford MM, Roufail S, Caesar C, Achen MG. A simple bioassay for the evaluation of vascular endothelial growth factors. J Vis Exp. 2016.

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    Stacker SA, Stenvers K, Caesar C, Vitali A, Domagala T, Nice E, Roufail S, Simpson RJ, Moritz R, Karpanen T, Alitalo K, Achen MG. Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers. J Biol Chem. 1999;274(45):32127-32136.

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    Korn C, Augustin HG. Mechanisms of vessel pruning and regression. Dev Cell. 2015;34(1):5-17.

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    Nakatsu MN, Hughes CC. An optimized three-dimensional in vitro model for the analysis of angiogenesis. Methods Enzymol. 2008;443:65-82.

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73. 73.

    Nakatsu MN, Davis J, Hughes CC. Optimized fibrin gel bead assay for the study of angiogenesis. J Vis Exp. 2007;3:186.

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74. 74.

    Alghanem AF, Wilkinson EL, Emmett MS, Aljasir MA, Holmes K, Rothermel BA, Simms VA, Heath VL, Cross MJ. RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells. Angiogenesis. 2017;20(3):341-358.

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75. 75.

    Newman AC, Nakatsu MN, Chou W, Gershon PD, Hughes CC. The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation. Mol Biol Cell. 2011;22(20):3791-3800.

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76. 76.

    Gau D, Veon W, Capasso TL, Bottcher R, Shroff S, Roman BL, Roy P. Pharmacological intervention of MKL/SRF signaling by CCG-1423 impedes endothelial cell migration and angiogenesis. Angiogenesis. 2017;20(4):663-672.

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77. 77.

    Torres-Estay V, Carreno DV, Fuenzalida P, Watts A, San Francisco IF, Montecinos VP, Sotomayor PC, Ebos J, Smith GJ, Godoy AS. Androgens modulate male-derived endothelial cell homeostasis using androgen receptor-dependent and receptor-independent mechanisms. Angiogenesis. 2017;20(1):25-38.

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78. 78.

    Merjaneh M, Langlois A, Larochelle S, Cloutier CB, Ricard-Blum S, Moulin VJ. Pro-angiogenic capacities of microvesicles produced by skin wound myofibroblasts. Angiogenesis. 2017;20(3):385-398.

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79. 79.

    Montesano R, Orci L, Vassalli P. In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices. J Cell Biol. 1983;97(5 Pt 1):1648-1652.

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80. 80.

    Davis GE, Kim DJ, Meng CX, Norden PR, Speichinger KR, Davis MT, Smith AO, Bowers SL, Stratman AN. Control of vascular tube morphogenesis and maturation in 3D extracellular matrices by endothelial cells and pericytes. Methods Mol Biol. 2013;1066:17-28.

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81. 81.

    Stahl A, Connor KM, Sapieha P, Chen J, Dennison RJ, Krah NM, Seaward MR, Willett KL, Aderman CM, Guerin KI, Hua J, Lofqvist C, Hellstrom A, Smith LE. The mouse retina as an angiogenesis model. Invest Ophthalmol Vis Sci. 2010;51(6):2813-2826.

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    Park SO, Wankhede M, Lee YJ, Choi EJ, Fliess N, Choe SW, Oh SH, Walter G, Raizada MK, Sorg BS, Oh SP. Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia. J Clin Invest. 2009;119(11):3487-3496.

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    Murakami T, Suzuma K, Takagi H, Kita M, Ohashi H, Watanabe D, Ojima T, Kurimoto M, Kimura T, Sakamoto A, Unoki N, Yoshimura N. Time-lapse imaging of vitreoretinal angiogenesis originating from both quiescent and mature vessels in a novel ex vivo system. Invest Ophthalmol Vis Sci. 2006;47(12):5529-5536.

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    Baker M, Robinson SD, Lechertier T, Barber PR, Tavora B, D’Amico G, Jones DT, Vojnovic B, Hodivala-Dilke K. Use of the mouse aortic ring assay to study angiogenesis. Nat Protoc. 2011;7(1):89-104.

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    Wang X, Phan DTT, George SC, Hughes CCW, Lee AP. 3D anastomosed microvascular network model with living capillary networks and endothelial cell-lined microfluidic channels. Methods Mol Biol. 2017;1612:325-344.

    Not in our library10.1007/978-1-4939-7021-6_24

91. 91.

    Shirure VS, Lezia A, Tao A, Alonzo LF, George SC. Low levels of physiological interstitial flow eliminate morphogen gradients and guide angiogenesis. Angiogenesis. 2017;20(4):493-504.

    Not in our library10.1007/s10456-017-9559-4

92. 92.

    Wang X, Phan DTT, Zhao D, George SC, Hughes CCW, Lee AP. An on-chip microfluidic pressure regulator that facilitates reproducible loading of cells and hydrogels into microphysiological system platforms. Lab Chip. 2016;16(5):868-876.

    Not in our library10.1039/c5lc01563d

93. 93.

    Wang X, Phan DT, Sobrino A, George SC, Hughes CC, Lee AP. Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels. Lab Chip. 2016;16(2):282-290.

    Not in our library10.1039/c5lc01050k

94. 94.

    Crampton SP, Davis J, Hughes CC. Isolation of human umbilical vein endothelial cells (HUVEC). J Vis Exp. 2007;3:183.

    Not in our library10.3791/183

95. 95.

    Melero-Martin JM, Bischoff J. Chapter 13. An in vivo experimental model for postnatal vasculogenesis. Methods Enzymol. 2008;445:303-329.

    Not in our library10.1016/s0076-6879(08)03013-9

96. 96.

    Gambino TJ, Williams SP, Caesar C, Resnick D, Nowell CJ, Farnsworth RH, Achen MG, Stacker SA, Karnezis TA. A three-dimensional lymphatic endothelial cell tube formation assay to identify novel kinases involved in lymphatic vessel remodeling. Ass Drug Dev Technol. 2017.

    Not in our library10.1089/adt.2016.764

97. 97.

    Phan DTT, Wang X, Craver BM, Sobrino A, Zhao D, Chen JC, Lee LYN, George SC, Lee AP, Hughes CCW. A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications. Lab Chip. 2017;17(3):511-520.

    Not in our library10.1039/c6lc01422d

98. 98.

    Nicosia RF, Tchao R, Leighton J. Histotypic angiogenesis in vitro: light microscopic, ultrastructural, and radioautographic studies. In vitro. 1982;18:538-549.

    Not in our library10.1007/bf02810077

99. 99.

    Nicosia RF, Ottinetti A. Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro. Lab Investig J Techn Methods Pathol. 1990;63(1):115-122.

    Not in our library

100. 100.

     Nicosia RF. The aortic ring model of angiogenesis: a quarter century of search and discovery. J Cell Mol Med. 2009;13:4113-4136.

     Not in our library10.1111/j.1582-4934.2009.00891.x

101. 101.

     Gao N, Liu X, Wu J, Li J, Dong C, Wu X, Xiao X, Yu FX. CXCL10 suppression of hem- and lymph-angiogenesis in inflamed corneas through MMP13. Angiogenesis. 2017;20(4):505-518.

     Not in our library10.1007/s10456-017-9561-x

102. 102.

     Seano G, Chiaverina G, Gagliardi PA, di Blasio L, Sessa R, Bussolino F, Primo L. Modeling human tumor angiogenesis in a three-dimensional culture system. Blood. 2013;121(21):e129-e137.

     Not in our library10.1182/blood-2012-08-452292

103. 103.

     Aplin AC, Fogel E, Zorzi P, Nicosia RF. The aortic ring model of angiogenesis. Methods Enzymol. 2008;443:119-136.

     Not in our library10.1016/s0076-6879(08)02007-7

104. 104.

     Nicosia R, Ligresti G, Aplin AC, Zudaire E, Cuttitta F. Preparation and analysis of aortic ring cultures for the study of angiogenesis ex vivo. The textbook of angiogenesis and lymphangiogenesis: Methods and Applications. 2012;127-148.

     Not in our library

105. 105.

     Blacher S, Devy L, Burbridge MF, Roland G, Tucker G, Noel A, Foidart JM. Improved quantification of angiogenesis in the rat aortic ring assay. Angiogenesis. 2001;4(2):133-142.

     Not in our library10.1023/a:1012251229631

106. 106.

     Blatt RJ, Clark AN, Courtney J, Tully C, Tucker AL. Automated quantitative analysis of angiogenesis in the rat aorta model using. Image-Pro Plus 4.1. Comput Methods Programs Biomed. 2004;75:75-79.

     Not in our library10.1016/j.cmpb.2003.11.001

107. 107.

     Nissanov J, Tuman RW, Gruver LM, Fortunato JM. Automatic vessel segmentation and quantification of the rat aortic ring assay of angiogenesis. Lab Investig J Tech Methods Pathol. 1995;73:734-739.

     Not in our library

108. 108.

     Zorzi P, Aplin AC, Smith KD, Nicosia RF. Technical Advance: the rat aorta contains resident mononuclear phagocytes with proliferative capacity and proangiogenic properties. J LeukocBiol. 2010;88:1051-1059.

     Not in our library10.1189/jlb.0310178

109. 109.

     Masson VV, Devy L, Grignet-Debrus C, Bernt S, Bajou K, Blacher S, Roland G, Chang Y, Fong T, Carmeliet P, Foidart JM, Noel A. Mouse Aortic ring assay: a new approach of the molecular genetics of angiogenesis. Biol Proced Online. 2002;4:24-31.

     Not in our library10.1251/bpo30

110. 110.

     Malinda KM, Nomizu M, Chung M, Delgado M, Kuratomi Y, Yamada Y, Kleinman HK, Ponce ML. Identification of laminin alpha1 and beta1 chain peptides active for endothelial cell adhesion, tube formation, and aortic sprouting. FASEB J. 1999;13(1):53-62.

     Not in our library

111. 111.

     Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis—correlation in invasive breast carcinoma. N Engl J Med. 1991;324(1):1-8.

     Not in our library10.1056/nejm199101033240101

112. 112.
     Development and Validation of a Histological Method to Measure Microvessel Density in Whole-Slide Images of Cancer Tissue. · 2016

     Not checked
113. 113.

     Uzzan B, Nicolas P, Cucherat M, Perret GY. Microvessel density as a prognostic factor in women with breast cancer: a systematic review of the literature and meta-analysis. Can Res. 2004;64(9):2941-2955.

     Not in our library10.1158/0008-5472.can-03-1957

114. 114.

     Bais C, Mueller B, Brady MF, Mannel RS, Burger RA, Wei W, Marien KM, Kockx MM, Husain A, Birrer MJ. Tumor microvessel density as a potential predictive marker for bevacizumab benefit: GOG-0218 biomarker analyses. J Natl Cancer Inst. 2017.

     Not in our library10.1093/jnci/djx066

115. 115.

     Griffioen AW, Mans LA, de Graaf AM, Nowak-Sliwinska P, de Hoog CL, de Jong TA, Vyth-Dreese FA, van Beijnum JR, Bex A, Jonasch E. Rapid angiogenesis onset after discontinuation of sunitinib treatment of renal cell carcinoma patients. Clin Cancer Res. 2012;18(14):3961-3971.

     Not in our library10.1158/1078-0432.ccr-12-0002

116. 116.

     Vermeulen PB, Gasparini G, Fox SB, Colpaert C, Marson LP, Gion M, Belien JA, de Waal RM, Van Marck E, Magnani E, Weidner N, Harris AL, Dirix LY. Second international consensus on the methodology and criteria of evaluation of angiogenesis quantification in solid human tumours. Eur J Cancer. 2002;38(12):1564-1579.

     Not in our library10.1016/s0959-8049(02)00094-1

117. 117.
     Vessel co‐option in primary human tumors and metastases: an obstacle to effective anti‐angiogenic treatment? · 2013

     No notice
118. 118.

     Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst. 1990;82(1):4-6.

     Not in our library10.1093/jnci/82.1.4

119. 119.

     Frentzas S, Simoneau E, Bridgeman VL, Vermeulen PB, Foo S, Kostaras E, Nathan M, Wotherspoon A, Gao ZH, Shi Y, Van den Eynden G, Daley F, Peckitt C, Tan X, Salman A, Lazaris A, Gazinska P, Berg TJ, Eltahir Z, Ritsma L, Van Rheenen J, Khashper A, Brown G, Nystrom H, Sund M, Van Laere S, Loyer E, Dirix L, Cunningham D, Metrakos P, Reynolds AR. Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases. Nat Med. 2016;22(11):1294-1302.

     Not in our library10.1038/nm.4197

120. 120.

     van Dam PJ, van der Stok EP, Teuwen LA, Van den Eynden GG, Illemann M, Frentzas S, Majeed AW, Eefsen RL, Coebergh van den Braak RRJ, Lazaris A, Fernandez MC, Galjart B, Laerum OD, Rayes R, Grunhagen DJ, Van de Paer M, Sucaet Y, Mudhar HS, Schvimer M, Nystrom H, Kockx M, Bird NC, Vidal-Vanaclocha F, Metrakos P, Simoneau E, Verhoef C, Dirix LY, Van Laere S, Gao ZH, Brodt P, Reynolds AR, Vermeulen PB. International consensus guidelines for scoring the histopathological growth patterns of liver metastasis. Br J Cancer. 2017;117(10):1427-1441.

     Not in our library10.1038/bjc.2017.334

121. 121.

     Pezzella F, Pastorino U, Tagliabue E, Andreola S, Sozzi G, Gasparini G, Menard S, Gatter KC, Harris AL, Fox S, Buyse M, Pilotti S, Pierotti M, Rilke F. Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis. Am J Pathol. 1997;151(5):1417-1423.

     Not in our library

122. 122.
     Vessel co‐option is common in human lung metastases and mediates resistance to anti‐angiogenic therapy in preclinical lung metastasis models · 2016

     No notice
123. 123.

     St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW. Genes expressed in human tumor endothelium. Science. 2000;289(5482):1197-1202.

     Not in our library10.1126/science.289.5482.1197

124. 124.

     van Beijnum JR, Dings RP, van der Linden E, Zwaans BM, Ramaekers FC, Mayo KH, Griffioen AW. Gene expression of tumor angiogenesis dissected: specific targeting of colon cancer angiogenic vasculature. Blood. 2006;108(7):2339-2348.

     Not in our library10.1182/blood-2006-02-004291

125. 125.

     van Beijnum JR, Eijgelaar WJ, Griffioen AW. Towards high-throughput functional target discovery in angiogenesis research. Trends Mol Med. 2006;12(1):44-52.

     Not in our library10.1016/j.molmed.2005.11.005

126. 126.

     Masiero M, Simoes FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, Li JL, Patient R, Sood AK, Banham AH, Harris AL, Buffa FM. A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. Cancer Cell. 2013;24(2):229-241.

     Not in our library10.1016/j.ccr.2013.06.004

127. 127.

     Mura M, Swain RK, Zhuang X, Vorschmitt H, Reynolds G, Durant S, Beesley JF, Herbert JM, Sheldon H, Andre M, Sanderson S, Glen K, Luu NT, McGettrick HM, Antczak P, Falciani F, Nash GB, Nagy ZS, Bicknell R. Identification and angiogenic role of the novel tumor endothelial marker CLEC14A. Oncogene. 2012;31(3):293-305.

     Not in our library10.1038/onc.2011.233

128. 128.

     Passalidou E, Trivella M, Singh N, Ferguson M, Hu J, Cesario A, Granone P, Nicholson AG, Goldstraw P, Ratcliffe C, Tetlow M, Leigh I, Harris AL, Gatter KC, Pezzella F. Vascular phenotype in angiogenic and non-angiogenic lung non-small cell carcinomas. Br J Cancer. 2002;86(2):244-249.

     Not in our library10.1038/sj.bjc.6600015

129. 129.

     Motz GT, Coukos G. The parallel lives of angiogenesis and immunosuppression: cancer and other tales. Nat Rev Immunol. 2011;11(10):702-711.

     Not in our library10.1038/nri3064

130. 130.

     Griffioen AW, Damen CA, Blijham GH, Groenewegen G. Tumor angiogenesis is accompanied by a decreased inflammatory response of tumor-associated endothelium. Blood. 1996;88(2):667-673.

     Not in our library

131. 131.

     Griffioen AW, Damen CA, Martinotti S, Blijham GH, Groenewegen G. Endothelial intercellular adhesion molecule-1 expression is suppressed in human malignancies: the role of angiogenic factors. Can Res. 1996;56(5):1111-1117.

     Not in our library

132. 132.

     Ramjiawan RR, Griffioen AW, Duda DG. Anti-angiogenesis for cancer revisited: is there a role for combinations with immunotherapy? Angiogenesis. 2017;20(2):185-204.

     Not in our library10.1007/s10456-017-9552-y

133. 133.

     Croci DO, Cerliani JP, Dalotto-Moreno T, Mendez-Huergo SP, Mascanfroni ID, Dergan-Dylon S, Toscano MA, Caramelo JJ, Garcia-Vallejo JJ, Ouyang J, Mesri EA, Junttila MR, Bais C, Shipp MA, Salatino M, Rabinovich GA. Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors. Cell. 2014;156(4):744-758.

     Not in our library10.1016/j.cell.2014.01.043

134. 134.

     Betz C, Lenard A, Belting HG, Affolter M. Cell behaviors and dynamics during angiogenesis. Development. 2016;143(13):2249-2260.

     Not in our library10.1242/dev.135616

135. 135.

     Hlushchuk R, Makanya AN, Djonov V. Escape mechanisms after antiangiogenic treatment, or why are the tumors growing again? Int J Dev Biol. 2011;55(4–5):563-567.

     Not in our library10.1387/ijdb.103231rh

136. 136.

     Burri PH, Tarek MR. A novel mechanism of capillary growth in the rat pulmonary microcirculation. The Anatomical record. 1990;228(1):35-45.

     Not in our library10.1002/ar.1092280107

137. 137.

     Djonov V, Schmid M, Tschanz SA, Burri PH. Intussusceptive angiogenesis: its role in embryonic vascular network formation. Circ Res. 2000;86(3):286-292.

     Not in our library10.1161/01.res.86.3.286

138. 138.

     Karthik S, Djukic T, Kim J-D, Zuber B, Makanya A, Odriozola A, Hlushchuk R, Filipovic N, Jin SW, Djonov V. Synergistic interaction of sprouting and intussusceptive angiogenesis during zebrafish caudal vein plexus development. Sci Rep.

     Not in our library10.1038/s41598-018-27791-6

139. 139.

     Schaad L, Hlushchuk R, Barre S, Gianni-Barrera R, Haberthur D, Banfi A, Djonov V. Correlative imaging of the murine hind limb vasculature and muscle tissue by MicroCT and light microscopy. Sci Rep. 2017;7:41842.

     Not in our library10.1038/srep41842

140. 140.

     Petrova TV, Koh GY. Organ-specific lymphatic vasculature: from development to pathophysiology. J Exp Med. 2018;215(1):35-49.

     Not in our library10.1084/jem.20171868

141. 141.

     Aspelund A, Robciuc MR, Karaman S, Makinen T, Alitalo K. Lymphatic system in cardiovascular medicine. Circ Res. 2016;118(3):515-530.

     Not in our library10.1161/circresaha.115.306544

142. 142.

     Jeltsch M, Kaipainen A, Joukov V, Meng X, Lakso M, Rauvala H, Swartz M, Fukumura D, Jain RK, Alitalo K. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science. 1997;276(5317):1423-1425.

     Not in our library10.1126/science.276.5317.1423

143. 143.

     Anisimov A, Alitalo A, Korpisalo P, Soronen J, Kaijalainen S, Leppanen VM, Jeltsch M, Yla-Herttuala S, Alitalo K. Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle. Circ Res. 2009;104(11):1302-1312.

     Not in our library10.1161/circresaha.109.197830

144. 144.

     He Y, Kozaki K, Karpanen T, Koshikawa K, Yla-Herttuala S, Takahashi T, Alitalo K. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling. J Natl Cancer Inst. 2002;94(11):819-825.

     Not in our library10.1093/jnci/94.11.819

145. 145.

     Garcia-Caballero M, Van de Velde M, Blacher S, Lambert V, Balsat C, Erpicum C, Durre T, Kridelka F, Noel A. Modeling pre-metastatic lymphvascular niche in the mouse ear sponge assay. Sci Rep. 2017;7:41494.

     Not in our library10.1038/srep41494

146. 146.

     Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA. Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis. Can Res. 2010;70(8):3042-3051.

     Not in our library10.1158/0008-5472.can-09-3761

147. 147.

     Hirakawa S, Brown LF, Kodama S, Paavonen K, Alitalo K, Detmar M. VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites. Blood. 2007;109(3):1010-1017.

     Not in our library10.1182/blood-2006-05-021758

148. 148.

     Kholova I, Koota S, Kaskenpaa N, Leppanen P, Narvainen J, Kavec M, Rissanen TT, Hazes T, Korpisalo P, Grohn O, Yla-Herttuala S. Adenovirus-mediated gene transfer of human vascular endothelial growth factor-d induces transient angiogenic effects in mouse hind limb muscle. Hum Gene Ther. 2007;18(3):232-244.

     Not in our library10.1089/hum.2006.100

149. 149.

     Rissanen TT, Markkanen JE, Gruchala M, Heikura T, Puranen A, Kettunen MI, Kholova I, Kauppinen RA, Achen MG, Stacker SA, Alitalo K, Yla-Herttuala S. VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses. Circ Res. 2003;92(10):1098-1106.

     Not in our library10.1161/01.res.0000073584.46059.e3

150. 150.

     Joukov V, Kumar V, Sorsa T, Arighi E, Weich H, Saksela O, Alitalo K. A recombinant mutant vascular endothelial growth factor-C that has lost vascular endothelial growth factor receptor-2 binding, activation, and vascular permeability activities. J Biol Chem. 1998;273(12):6599-6602.

     Not in our library10.1074/jbc.273.12.6599

151. 151.

     Inagaki K, Fuess S, Storm TA, Gibson GA, McTiernan CF, Kay MA, Nakai H. Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8. Mol Ther. 2006;14(1):45-53.

     Not in our library10.1016/j.ymthe.2006.03.014

152. 152.

     Stratman AN, Davis GE. Endothelial cell-pericyte interactions stimulate basement membrane matrix assembly: influence on vascular tube remodeling, maturation, and stabilization. Microsc Microanal. 2012;18(1):68-80.

     Not in our library10.1017/s1431927611012402

153. 153.

     Stratman AN, Malotte KM, Mahan RD, Davis MJ, Davis GE. Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood. 2009;114(24):5091-5101.

     Not in our library10.1182/blood-2009-05-222364

154. 154.

     Stratman AN, Schwindt AE, Malotte KM, Davis GE. Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization. Blood. 2010;116(22):4720-4730.

     Not in our library10.1182/blood-2010-05-286872

155. 155.

     Bowers SL, Norden PR, Davis GE. Molecular signaling pathways controlling vascular tube morphogenesis and pericyte-induced tube maturation in 3D extracellular matrices. Adv Pharmacol. 2016;77:241-280.

     Not in our library10.1016/bs.apha.2016.04.005

156. 156.

     Stratman AN, Davis MJ, Davis GE. VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines. Blood. 2011;117(14):3709-3719.

     Not in our library10.1182/blood-2010-11-316752

157. 157.

     Smith AO, Bowers SL, Stratman AN, Davis GE. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions. PLoS ONE. 2013;8(12):e85147.

     Not in our library10.1371/journal.pone.0085147

158. 158.

     Stratman AN, Saunders WB, Sacharidou A, Koh W, Fisher KE, Zawieja DC, Davis MJ, Davis GE. Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices. Blood. 2009;114(2):237-247.

     Not in our library10.1182/blood-2008-12-196451

159. 159.

     Senger DR, Davis GE. Angiogenesis. Cold Spring Harb Perspect Biol. 2011;3(8):a005090.

     Not in our library10.1101/cshperspect.a005090

160. 160.

     Koh W, Stratman AN, Sacharidou A, Davis GE. In vitro three dimensional collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis. Methods Enzymol. 2008;443:83-101.

     Not in our library10.1016/s0076-6879(08)02005-3

161. 161.

     Folkman J, Hochberg M. Self-regulation of growth in three dimensions. J Exp Med. 1973;138(4):745-753.

     Not in our library10.1084/jem.138.4.745

162. 162.

     Wigle JC, Sutherland RM. Increased thermoresistance developed during growth of small multicellular spheroids. J Cell Physiol. 1985;122(2):281-289.

     Not in our library10.1002/jcp.1041220218

163. 163.

     Xu R, Boudreau A, Bissell MJ. Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices. Cancer Metastasis Rev. 2009;28(1–2):167-176.

     Not in our library10.1007/s10555-008-9178-z

164. 164.

     Upreti M, Jamshidi-Parsian A, Koonce NA, Webber JS, Sharma SK, Asea AA, Mader MJ, Griffin RJ. Tumor-endothelial cell three-dimensional spheroids: new aspects to enhance radiation and drug therapeutics. Transl Oncol. 2011;4(6):365-376.

     Not in our library10.1593/tlo.11187

165. 165.
     Halfway between 2D and Animal Models: Are 3D Cultures the Ideal Tool to Study Cancer-Microenvironment Interactions? · 2018

     No notice
166. 166.

     Timmins NE, Dietmair S, Nielsen LK. Hanging-drop multicellular spheroids as a model of tumour angiogenesis. Angiogenesis. 2004;7(2):97-103.

     Not in our library10.1007/s10456-004-8911-7

167. 167.

     Patti GJ, Yanes O, Siuzdak G. Innovation: metabolomics: the apogee of the omics trilogy. Nat Rev Mol Cell Biol. 2012;13(4):263-269.

     Not in our library10.1038/nrm3314

168. 168.

     Potente M, Gerhardt H, Carmeliet P. Basic and therapeutic aspects of angiogenesis. Cell. 2011;146(6):873-887.

     Not in our library10.1016/j.cell.2011.08.039

169. 169.

     Schoors S, Bruning U, Missiaen R, Queiroz KC, Borgers G, Elia I, Zecchin A, Cantelmo AR, Christen S, Goveia J, Heggermont W, Godde L, Vinckier S, Van Veldhoven PP, Eelen G, Schoonjans L, Gerhardt H, Dewerchin M, Baes M, De Bock K, Ghesquiere B, Lunt SY, Fendt SM, Carmeliet P. Fatty acid carbon is essential for dNTP synthesis in endothelial cells. Nature. 2015;520(7546):192-197.

     Not in our library10.1038/nature14362

170. 170.

     De Bock K, Georgiadou M, Schoors S, Kuchnio A, Wong BW, Cantelmo AR, Quaegebeur A, Ghesquiere B, Cauwenberghs S, Eelen G, Phng LK, Betz I, Tembuyser B, Brepoels K, Welti J, Geudens I, Segura I, Cruys B, Bifari F, Decimo I, Blanco R, Wyns S, Vangindertael J, Rocha S, Collins RT, Munck S, Daelemans D, Imamura H, Devlieger R, Rider M, Van Veldhoven PP, Schuit F, Bartrons R, Hofkens J, Fraisl P, Telang S, Deberardinis RJ, Schoonjans L, Vinckier S, Chesney J, Gerhardt H, Dewerchin M, Carmeliet P. Role of PFKFB3-driven glycolysis in vessel sprouting. Cell. 2013;154(3):651-663.

     Not in our library10.1016/j.cell.2013.06.037

171. 171.

     Potente M, Carmeliet P. The Link Between Angiogenesis and Endothelial Metabolism. Annu Rev Physiol. 2017;79:43-66.

     Not in our library10.1146/annurev-physiol-021115-105134

172. 172.

     Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, Kimmelman AC, Locasale JW, Lunt SY, Maddocks OD, Malloy C, Metallo CM, Meuillet EJ, Munger J, Noh K, Rabinowitz JD, Ralser M, Sauer U, Stephanopoulos G, St-Pierre J, Tennant DA, Wittmann C, Vander Heiden MG, Vazquez A, Vousden K, Young JD, Zamboni N, Fendt SM. A roadmap for interpreting (13)C metabolite labeling patterns from cells. Curr Opin Biotechnol. 2015;34:189-201.

     Not in our library10.1016/j.copbio.2015.02.003

173. 173.

     Huang H, Vandekeere S, Kalucka J, Bierhansl L, Zecchin A, Bruning U, Visnagri A, Yuldasheva N, Goveia J, Cruys B, Brepoels K, Wyns S, Rayport S, Ghesquiere B, Vinckier S, Schoonjans L, Cubbon R, Dewerchin M, Eelen G, Carmeliet P. Role of glutamine and interlinked asparagine metabolism in vessel formation. EMBO J. 2017;36(16):2334-2352.

     Not in our library10.15252/embj.201695518

174. 174.

     Verdegem D, Moseley HNB, Vermaelen W, Sanchez AA, Ghesquiere B. MAIMS: a software tool for sensitive metabolic tracer analysis through the deconvolution of C-13 mass isotopologue profiles of large composite metabolites. Metabolomics. 2017;13(10):123.

     Not in our library

175. 175.

     Martano G, Delmotte N, Kiefer P, Christen P, Kentner D, Bumann D, Vorholt JA. Fast sampling method for mammalian cell metabolic analyses using liquid chromatography-mass spectrometry. Nat Protoc. 2015;10(1):1-11.

     Not in our library10.1038/nprot.2014.198

176. 176.

     Lu W, Su X, Klein MS, Lewis IA, Fiehn O, Rabinowitz JD. Metabolite measurement: pitfalls to avoid and practices to follow. Annu Rev Biochem. 2017;86:277-304.

     Not in our library10.1146/annurev-biochem-061516-044952

177. 177.

     Yuan M, Breitkopf SB, Yang X, Asara JM. A positive/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue. Nat Protoc. 2012;7(5):872-881.

     Not in our library10.1038/nprot.2012.024

178. 178.

     Lu W, Clasquin MF, Melamud E, Amador-Noguez D, Caudy AA, Rabinowitz JD. Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer. Anal Chem. 2010;82(8):3212-3221.

     Not in our library10.1021/ac902837x

179. 179.
     Bioinformatics Tools for Mass Spectroscopy-Based Metabolomic Data Processing and Analysis · 2012

     No notice
180. 180.

     Fernandez CA, Des Rosiers C, Previs SF, David F, Brunengraber H. Correction of 13C mass isotopomer distributions for natural stable isotope abundance. J Mass Spectrom. 1996;31(3):255-262.

     Not in our library10.1002/(sici)1096-9888(199603)31:3<255::aid-jms290>3.0.co;2-3

181. 181.

     Neely JR, Denton RM, England PJ, Randle PJ. The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart. Biochem J. 1972;128(1):147-159.

     Not in our library10.1042/bj1280147

182. 182.

     Yi W, Clark PM, Mason DE, Keenan MC, Hill C, Goddard WA, Peters EC, Driggers EM, Hsieh-Wilson LC. Phosphofructokinase 1 glycosylation regulates cell growth and metabolism. Science. 2012;337(6097):975-980.

     Not in our library10.1126/science.1222278

183. 183.

     Zhang J, Nuebel E, Wisidagama DR, Setoguchi K, Hong JS, Van Horn CM, Imam SS, Vergnes L, Malone CS, Koehler CM, Teitell MA. Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells. Nat Protoc. 2012;7(6):1068-1085.

     Not in our library10.1038/nprot.2012.048

184. 184.

     Dranka BP, Benavides GA, Diers AR, Giordano S, Zelickson BR, Reily C, Zou L, Chatham JC, Hill BG, Zhang J, Landar A, Darley-Usmar VM. Assessing bioenergetic function in response to oxidative stress by metabolic profiling. Free Radic Biol Med. 2011;51(9):1621-1635.

     Not in our library10.1016/j.freeradbiomed.2011.08.005

185. 185.

     Sauer U. Metabolic networks in motion: 13C-based flux analysis. Mol Syst Biol. 2006;2:62.

     Not in our library10.1038/msb4100109

186. 186.

     Kalucka J, Missiaen R, Georgiadou M, Schoors S, Lange C, De Bock K, Dewerchin M, Carmeliet P. Metabolic control of the cell cycle. Cell Cycle. 2015;14(21):3379-3388.

     Not in our library10.1080/15384101.2015.1090068

187. 187.

     DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci USA. 2007;104(49):19345-19350.

     Not in our library10.1073/pnas.0709747104

188. 188.

     Weissman IL, Anderson DJ, Gage F. Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. Annu Rev Cell Dev Biol. 2001;17:387-403.

     Not in our library10.1146/annurev.cellbio.17.1.387

189. 189.

     Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, Isner JM. Isolation of putative progenitor endothelial cells for angiogenesis. Science. 1997;275(5302):964-967.

     Not in our library10.1126/science.275.5302.964

190. 190.

     Medina RJ, Barber CL, Sabatier F, Dignat-George F, Melero-Martin JM, Khosrotehrani K, Ohneda O, Randi AM, Chan JKY, Yamaguchi T, Van Hinsbergh VWM, Yoder MC, Stitt AW. Endothelial progenitors: a consensus statement on nomenclature. Stem Cells Transl Med. 2017;6(5):1316-1320.

     Not in our library10.1002/sctm.16-0360

191. 191.

     Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N, Urbich C, Willeit J, Steiner M, Breuss J, Xu Q, Kiechl S, Mayr M. Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Blood. 2009;114(3):723-732.

     Not in our library10.1182/blood-2009-02-205930

192. 192.

     Shlush LI, Mitchell A, Heisler L, Abelson S, Ng SWK, Trotman-Grant A, Medeiros JJF, Rao-Bhatia A, Jaciw-Zurakowsky I, Marke R, McLeod JL, Doedens M, Bader G, Voisin V, Xu C, McPherson JD, Hudson TJ, Wang JCY, Minden MD, Dick JE. Tracing the origins of relapse in acute myeloid leukaemia to stem cells. Nature. 2017;547(7661):104-108.

     Not in our library10.1038/nature22993

193. 193.

     Rizvi AH, Camara PG, Kandror EK, Roberts TJ, Schieren I, Maniatis T, Rabadan R. Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development. Nat Biotechnol. 2017;35(6):551-560.

     Not in our library10.1038/nbt.3854

194. 194.

     Patel JK, Rao Y, Strachan P. Impact of pulmonary capillary wedge pressure on long-term mortality in patients with pulmonary arterial hypertension treated with parenteral trepostinil. Heart Lung Circ. 2017.

     Not in our library10.1016/j.hlc.2017.02.015

195. 195.

     Lin Y, Weisdorf DJ, Solovey A, Hebbel RP. Origins of circulating endothelial cells and endothelial outgrowth from blood. J Clin Investig. 2000;105(1):71-77.

     Not in our library10.1172/jci8071

196. 196.

     Ingram DA, Mead LE, Tanaka H, Meade V, Fenoglio A, Mortell K, Pollok K, Ferkowicz MJ, Gilley D, Yoder MC. Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood. 2004;104(9):2752-2760.

     Not in our library10.1182/blood-2004-04-1396

197. 197.

     Prasain N, Lee MR, Vemula S, Meador JL, Yoshimoto M, Ferkowicz MJ, Fett A, Gupta M, Rapp BM, Saadatzadeh MR, Ginsberg M, Elemento O, Lee Y, Voytik-Harbin SL, Chung HM, Hong KS, Reid E, O’Neill CL, Medina RJ, Stitt AW, Murphy MP, Rafii S, Broxmeyer HE, Yoder MC. Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells. Nat Biotechnol. 2014;32(11):1151-1157.

     Not in our library10.1038/nbt.3048

198. 198.
     Generation of Functional Blood Vessels from a Single c-kit+ Adult Vascular Endothelial Stem Cell · 2012

     No notice
199. 199.

     Naito H, Kidoya H, Sakimoto S, Wakabayashi T, Takakura N. Identification and characterization of a resident vascular stem/progenitor cell population in preexisting blood vessels. EMBO J. 2012;31(4):842-855.

     Not in our library10.1038/emboj.2011.465

200. 200.

     Yu QC, Song W, Wang D, Zeng YA. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Res. 2016;26(10):1079-1098.

     Not in our library10.1038/cr.2016.85

201. 201.

     Patel J, Seppanen EJ, Rodero MP, Wong HY, Donovan P, Neufeld Z, Fisk NM, Francois M, Khosrotehrani K. Functional definition of progenitors versus mature endothelial cells reveals key SoxF-dependent differentiation process. Circulation. 2017;135(8):786-805.

     Not in our library10.1161/circulationaha.116.024754

202. 202.

     Akbari E, Spychalski GB, Song JW. Microfluidic approaches to the study of angiogenesis and the microcirculation. Microcirculation. 2017.

     Not in our library10.1111/micc.12363

203. 203.

     Wong KH, Chan JM, Kamm RD, Tien J. Microfluidic models of vascular functions. Annu Rev Biomed Eng. 2012;14:205-230.

     Not in our library10.1146/annurev-bioeng-071811-150052

204. 204.

     Huh D, Hamilton GA, Ingber DE. From 3D cell culture to organs-on-chips. Trends Cell Biol. 2011;21(12):745-754.

     Not in our library10.1016/j.tcb.2011.09.005

205. 205.

     Sackmann EK, Fulton AL, Beebe DJ. The present and future role of microfluidics in biomedical research. Nature. 2014;507(7491):181-189.

     Not in our library10.1038/nature13118

206. 206.

     Ackermann M, Kim YO, Wagner WL, Schuppan D, Valenzuela CD, Mentzer SJ, Kreuz S, Stiller D, Wollin L, Konerding MA. Effects of nintedanib on the microvascular architecture in a lung fibrosis model. Angiogenesis. 2017;20(3):359-372.

     Not in our library10.1007/s10456-017-9543-z

207. 207.

     Duffy DC, McDonald JC, Schueller OJ, Whitesides GM. Rapid prototyping of microfluidic systems in poly(dimethylsiloxane). Anal Chem. 1998;70(23):4974-4984.

     Not in our library10.1021/ac980656z

208. 208.

     Folch A, Toner M. Microengineering of cellular interactions. Annu Rev Biomed Eng. 2000;2(1):227-256.

     Not in our library10.1146/annurev.bioeng.2.1.227

209. 209.

     Khademhosseini A, Langer R, Borenstein J, Vacanti JP. Microscale technologies for tissue engineering and biology. Proc Natl Acad Sci USA. 2006;103(8):2480-2487.

     Not in our library10.1073/pnas.0507681102

210. 210.

     Whitesides GM, Ostuni E, Takayama S, Jiang X, Ingber DE. Soft lithography in biology and biochemistry. Annu Rev Biomed Eng. 2001;3(1):335-373.

     Not in our library10.1146/annurev.bioeng.3.1.335

211. 211.

     Zervantonakis IK, Kothapalli CR, Chung S, Sudo R, Kamm RD. Microfluidic devices for studying heterotypic cell–cell interactions and tissue specimen cultures under controlled microenvironments. Biomicrofluidics. 2011;5(1):13406.

     Not in our library10.1063/1.3553237

212. 212.

     Buchanan CF, Verbridge SS, Vlachos PP, Rylander MN. Flow shear stress regulates endothelial barrier function and expression of angiogenic factors in a 3D microfluidic tumor vascular model. Cell Adh Migr. 2014;8(5):517-524.

     Not in our library10.4161/19336918.2014.970001

213. 213.

     Ehsan SM, Welch-Reardon KM, Waterman ML, Hughes CC, George SC. A three-dimensional in vitro model of tumor cell intravasation. Integr Biol (Camb). 2014;6(6):603-610.

     Not in our library10.1039/c3ib40170g

214. 214.

     Lee H, Park W, Ryu H, Jeon NL. A microfluidic platform for quantitative analysis of cancer angiogenesis and intravasation. Biomicrofluidics. 2014;8(5):054102.

     Not in our library10.1063/1.4894595

215. 215.

     Zervantonakis IK, Hughes-Alford SK, Charest JL, Condeelis JS, Gertler FB, Kamm RD. Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function. Proc Natl Acad Sci USA. 2012;109(34):13515-13520.

     Not in our library10.1073/pnas.1210182109

216. 216.

     Hsu YH, Moya ML, Hughes CC, George SC, Lee AP. A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays. Lab Chip. 2013;13(15):2990-2998.

     Not in our library10.1039/c3lc50424g

217. 217.

     Kim S, Lee H, Chung M, Jeon NL. Engineering of functional, perfusable 3D microvascular networks on a chip. Lab Chip. 2013;13(8):1489-1500.

     Not in our library10.1039/c3lc41320a

218. 218.

     Truskey GA. Endothelial cell vascular smooth muscle cell co-culture assay for high throughput screening assays for discovery of anti-angiogenesis agents and other therapeutic molecules. Int J High Throughput Screen. 2010;2010(1):171-181.

     Not in our library10.2147/ijhts.s13459

219. 219.

     Zheng Y, Sun Y, Yu X, Shao Y, Zhang P, Dai G, Fu J. Angiogenesis in liquid tumors: an in vitro assay for leukemic-cell-induced bone marrow angiogenesis. Adv Healthc Mater. 2016;5(9):1014-1024.

     Not in our library10.1002/adhm.201501007

220. 220.

     Song JW, Daubriac J, Tse JM, Bazou D, Munn LL. RhoA mediates flow-induced endothelial sprouting in a 3-D tissue analogue of angiogenesis. Lab Chip. 2012;12(23):5000-5006.

     Not in our library10.1039/c2lc40389g

221. 221.

     Song JW, Munn LL. Fluid forces control endothelial sprouting. Proc Natl Acad Sci USA. 2011;108(37):15342-15347.

     Not in our library10.1073/pnas.1105316108

222. 222.

     Vickerman V, Kamm RD. Mechanism of a flow-gated angiogenesis switch: early signaling events at cell-matrix and cell-cell junctions. Integr Biol (Camb). 2012;4(8):863-874.

     Not in our library10.1039/c2ib00184e

223. 223.

     Kim S, Chung M, Jeon NL. Three-dimensional biomimetic model to reconstitute sprouting lymphangiogenesis in vitro. Biomaterials. 2016;78:115-128.

     Not in our library10.1016/j.biomaterials.2015.11.019

224. 224.

     Moldobaeva A, Jenkins J, Zhong Q, Wagner EM. Lymphangiogenesis in rat asthma model. Angiogenesis. 2017;20(1):73-84.

     Not in our library10.1007/s10456-016-9529-2

225. 225.

     Ghaffari S, Leask RL, Jones EA. Flow dynamics control the location of sprouting and direct elongation during developmental angiogenesis. Development. 2015;142(23):4151-4157.

     Not in our library10.1242/dev.128058

226. 226.

     Galie PA, Nguyen DH, Choi CK, Cohen DM, Janmey PA, Chen CS. Fluid shear stress threshold regulates angiogenic sprouting. Proc Natl Acad Sci USA. 2014;111(22):7968-7973.

     Not in our library10.1073/pnas.1310842111

227. 227.

     Song JW, Bazou D, Munn LL. Anastomosis of endothelial sprouts forms new vessels in a tissue analogue of angiogenesis. Integr Biol (Camb). 2012;4(8):857-862.

     Not in our library10.1039/c2ib20061a

228. 228.

     Ghaffari S, Leask RL, Jones EAV. Blood flow can signal during angiogenesis not only through mechanotransduction, but also by affecting growth factor distribution. Angiogenesis. 2017;20(3):373-384.

     Not in our library10.1007/s10456-017-9553-x

229. 229.

     Chrobak KM, Potter DR, Tien J. Formation of perfused, functional microvascular tubes in vitro. Microvasc Res. 2006;71(3):185-196.

     Not in our library10.1016/j.mvr.2006.02.005

230. 230.

     Jain RK, Munn LL, Fukumura D. Dissecting tumour pathophysiology using intravital microscopy. Nat Rev Cancer. 2002;2(4):266-276.

     Not in our library10.1038/nrc778

231. 231.

     Nagy JA, Vasile E, Feng D, Sundberg C, Brown LF, Detmar MJ, Lawitts JA, Benjamin L, Tan X, Manseau EJ. Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis. J Exp Med. 2002;196(11):1497-1506.

     Not in our library10.1084/jem.20021244

232. 232.

     Nguyen DH, Stapleton SC, Yang MT, Cha SS, Choi CK, Galie PA, Chen CS. Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro. Proc Natl Acad Sci USA. 2013;110(17):6712-6717.

     Not in our library10.1073/pnas.1221526110

233. 233.

     Bogorad MI, DeStefano J, Karlsson J, Wong AD, Gerecht S, Searson PC. Review: in vitro microvessel models. Lab Chip. 2015;15(22):4242-4255.

     Not in our library10.1039/c5lc00832h

234. 234.

     Bischel LL, Lee SH, Beebe DJ. A practical method for patterning lumens through ECM hydrogels via viscous finger patterning. J Lab Autom. 2012;17(2):96-103.

     Not in our library10.1177/2211068211426694

235. 235.

     Choi NW, Cabodi M, Held B, Gleghorn JP, Bonassar LJ, Stroock AD. Microfluidic scaffolds for tissue engineering. Nat Mater. 2007;6(11):908-915.

     Not in our library10.1038/nmat2022

236. 236.

     Zheng Y, Chen J, Craven M, Choi NW, Totorica S, Diaz-Santana A, Kermani P, Hempstead B, Fischbach-Teschl C, Lopez JA, Stroock AD. In vitro microvessels for the study of angiogenesis and thrombosis. Proc Natl Acad Sci USA. 2012;109(24):9342-9347.

     Not in our library10.1073/pnas.1201240109

237. 237.

     Bhattacharjee N, Urrios A, Kang S, Folch A. The upcoming 3D-printing revolution in microfluidics. Lab Chip. 2016;16(10):1720-1742.

     Not in our library10.1039/c6lc00163g

238. 238.

     Miller JS, Stevens KR, Yang MT, Baker BM, Nguyen DH, Cohen DM, Toro E, Chen AA, Galie PA, Yu X, Chaturvedi R, Bhatia SN, Chen CS. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. Nat Mater. 2012;11(9):768-774.

     Not in our library10.1038/nmat3357

239. 239.

     Li X, Soler M, Ozdemir CI, Belushkin A, Yesilkoy F, Altug H. Plasmonic nanohole array biosensor for label-free and real-time analysis of live cell secretion. Lab Chip. 2017;17(13):2208-2217.

     Not in our library10.1039/c7lc00277g

240. 240.

     Yu JQ, Liu XF, Chin LK, Liu AQ, Luo KQ. Study of endothelial cell apoptosis using fluorescence resonance energy transfer (FRET) biosensor cell line with hemodynamic micro-fluidic chip system. Lab Chip. 2013;13(14):2693-2700.

     Not in our library10.1039/c3lc50105a

241. 241.

     Berthier E, Young EW, Beebe D. Engineers are from PDMS-land, biologists are from Polystyrenia. Lab Chip. 2012;12(7):1224-1237.

     Not in our library10.1039/c2lc20982a

242. 242.

     Shirure VS, George SC. Design considerations to minimize the impact of drug absorption in polymer-based organ-on-a-chip platforms. Lab Chip. 2017;17(4):681-690.

     Not in our library10.1039/c6lc01401a

243. 243.

     Lorusso G, Ruegg C. The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem Cell Biol. 2008;130(6):1091-1103.

     Not in our library10.1007/s00418-008-0530-8

244. 244.

     Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell. 2012;21(3):309-322.

     Not in our library10.1016/j.ccr.2012.02.022

245. 245.

     Sleeman JP, Christofori G, Fodde R, Collard JG, Berx G, Decraene C, Ruegg C. Concepts of metastasis in flux: the stromal progression model. Semin Cancer Biol. 2012.

     Not in our library10.1016/j.semcancer.2012.02.007

246. 246.

     Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature. 2011;473(7347):298-307.

     Not in our library10.1038/nature10144

247. 247.

     Laurent J, Hull EF, Touvrey C, Kuonen F, Lan Q, Lorusso G, Doucey MA, Ciarloni L, Imaizumi N, Alghisi GC, Fagiani E, Zaman K, Stupp R, Shibuya M, Delaloye JF, Christofori G, Ruegg C. Proangiogenic factor PlGF programs CD11b(+) myelomonocytes in breast cancer during differentiation of their hematopoietic progenitors. Can Res. 2011;71(11):3781-3791.

     Not in our library10.1158/0008-5472.can-10-3684

248. 248.

     Solinas G, Germano G, Mantovani A, Allavena P. Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol. 2009;86(5):1065-1073.

     Not in our library10.1189/jlb.0609385

249. 249.

     Keskinov AA, Shurin MR. Myeloid regulatory cells in tumor spreading and metastasis. Immunobiology. 2015;220(2):236-242.

     Not in our library10.1016/j.imbio.2014.07.017

250. 250.

     Noy R, Pollard JW. Tumor-associated macrophages: from mechanisms to therapy. Immunity. 2014;41(1):49-61.

     Not in our library10.1016/j.immuni.2014.06.010

251. 251.

     Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature. 2005;438(7069):820-827.

     Not in our library10.1038/nature04186

252. 252.

     Huang B, Lei Z, Zhao J, Gong W, Liu J, Chen Z, Liu Y, Li D, Yuan Y, Zhang GM, Feng ZH. CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers. Cancer Lett. 2007;252(1):86-92.

     Not in our library10.1016/j.canlet.2006.12.012

253. 253.

     De Palma M, Venneri MA, Galli R, Sergi LS, Politi LS, Sampaolesi M, Naldini L. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell. 2005;8(3):211-226.

     Not in our library10.1016/j.ccr.2005.08.002

254. 254.

     Kuonen F, Laurent J, Secondini C, Lorusso G, Stehle JC, Rausch T, Faes-Van’t Hull E, Bieler G, Alghisi GC, Schwendener R, Andrejevic-Blant S, Mirimanoff RO, Ruegg C. Inhibition of the Kit ligand/c-Kit axis attenuates metastasis in a mouse model mimicking local breast cancer relapse after radiotherapy. Clin Cancer Res. 2012;18(16):4365-4374.

     Not in our library10.1158/1078-0432.ccr-11-3028

255. 255.

     Young YK, Bolt AM, Ahn R, Mann KK. Analyzing the tumor microenvironment by flow cytometry. Methods Mol Biol. 2016;1458:95-110.

     Not in our library10.1007/978-1-4939-3801-8_8

256. 256.

     Shapiro HM. The evolution of cytometers. Cytom A. 2004;58(1):13-20.

     Not in our library10.1002/cyto.a.10111

257. 257.

     Herzenberg LA, Parks D, Sahaf B, Perez O, Roederer M, Herzenberg LA. The history and future of the fluorescence activated cell sorter and flow cytometry: a view from Stanford. Clin Chem. 2002;48(10):1819-1827.

     Not in our library

258. 258.

     Chang Q, Hedley D. Emerging applications of flow cytometry in solid tumor biology. Methods. 2012;57(3):359-367.

     Not in our library10.1016/j.ymeth.2012.03.027

259. 259.

     Muppidi J, Porter M, Siegel RM. Measurement of apoptosis and other forms of cell death. Curr Protoc Immunol. 2004.

     Not in our library10.1002/0471142735.im0317s59

260. 260.

     Camplejohn RS. The measurement of intracellular antigens and DNA by multiparametric flow cytometry. J Microsc. 1994;176(Pt 1):1-7.

     Not in our library10.1111/j.1365-2818.1994.tb03493.x

261. 261.

     Lovelace P, Maecker HT. Multiparameter intracellular cytokine staining. Methods Mol Biol. 2018;1678:151-166.

     Not in our library10.1007/978-1-4939-7346-0_9

262. 262.

     Secondini C, Coquoz O, Spagnuolo L, Spinetti T, Peyvandi S, Ciarloni L, Botta F, Bourquin C, Ruegg C. Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade. Oncoimmunology. 2017;6(6):e1316437.

     Not in our library10.1080/2162402x.2017.1316437

263. 263.

     Cattin S, Fellay B, Pradervand S, Trojan A, Ruhstaller T, Ruegg C, Furstenberger G. Bevacizumab specifically decreases elevated levels of circulating KIT+ CD11b+ cells and IL-10 in metastatic breast cancer patients. Oncotarget. 2016;7(10):11137-11150.

     Not in our library10.18632/oncotarget.7097

264. 264.

     Guex N, Crespo I, Bron S, Ifticene-Treboux A, Faes-Van’t Hull E, Kharoubi S, Liechti R, Werffeli P, Ibberson M, Majo F, Nicolas M, Laurent J, Garg A, Zaman K, Lehr HA, Stevenson BJ, Ruegg C, Coukos G, Delaloye JF, Xenarios I, Doucey MA. Angiogenic activity of breast cancer patients’ monocytes reverted by combined use of systems modeling and experimental approaches. PLoS Comput Biol. 2015;11(3):e1004050.

     Not in our library10.1371/journal.pcbi.1004050

265. 265.

     Zumsteg A, Baeriswyl V, Imaizumi N, Schwendener R, Ruegg C, Christofori G. Myeloid cells contribute to tumor lymphangiogenesis. PLoS ONE. 2009;4(9):e7067.

     Not in our library10.1371/journal.pone.0007067

266. 266.

     Morgan E, Varro R, Sepulveda H, Ember JA, Apgar J, Wilson J, Lowe L, Chen R, Shivraj L, Agadir A, Campos R, Ernst D, Gaur A. Cytometric bead array: a multiplexed assay platform with applications in various areas of biology. Clin Immunol. 2004;110(3):252-266.

     Not in our library10.1016/j.clim.2003.11.017

267. 267.

     Kalluri R. The biology and function of exosomes in cancer. J Clin Invest. 2016;126(4):1208-1215.

     Not in our library10.1172/jci81135

268. 268.

     D’Souza-Schorey C, Clancy JW. Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers. Genes Dev. 2012;26(12):1287-1299.

     Not in our library10.1101/gad.192351.112

269. 269.

     Orozco AF, Lewis DE. Flow cytometric analysis of circulating microparticles in plasma. Cytom A. 2010;77(6):502-514.

     Not in our library10.1002/cyto.a.20886

270. 270.

     Laurent J, Touvrey C, Botta F, Kuonen F, Ruegg C. Emerging paradigms and questions on pro-angiogenic bone marrow-derived myelomonocytic cells. Int J Dev Biol. 2011;55(4–5):527-534.

     Not in our library10.1387/ijdb.103228jl

271. 271.

     Grutzkau A, Radbruch A. Small but mighty: how the MACS-technology based on nanosized superparamagnetic particles has helped to analyze the immune system within the last 20 years. Cytom A. 2010;77(7):643-647.

     Not in our library10.1002/cyto.a.20918

272. 272.

     Mocellin S, Wang E, Panelli M, Rossi CR, Marincola FM. Use of laser scanning cytometry to study tumor micro-environment. Histol Histopathol. 2003;18(2):609-615.

     Not in our library10.14670/hh-18.609

273. 273.

     Nolan JP, Condello D. Spectral flow cytometry. Curr Protoc Cytom. 2013.

     Not in our library10.1002/0471142956.cy0127s63

274. 274.

     Tuchin VV, Tarnok A, Zharov VP. In vivo flow cytometry: a horizon of opportunities. Cytom A. 2011;79(10):737-745.

     Not in our library10.1002/cyto.a.21143

275. 275.
     Guidelines for morpholino use in zebrafish · 2017

     No notice
276. 276.

     Kok FO, Shin M, Ni CW, Gupta A, Grosse AS, van Impel A, Kirchmaier BC, Peterson-Maduro J, Kourkoulis G, Male I, DeSantis DF, Sheppard-Tindell S, Ebarasi L, Betsholtz C, Schulte-Merker S, Wolfe SA, Lawson ND. Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish. Dev Cell. 2015;32(1):97-108.

     Not in our library10.1016/j.devcel.2014.11.018

277. 277.

     Rossi A, Kontarakis Z, Gerri C, Nolte H, Holper S, Kruger M, Stainier DY. Genetic compensation induced by deleterious mutations but not gene knockdowns. Nature. 2015;524(7564):230-233.

     Not in our library10.1038/nature14580

278. 278.
     Frameshift indels introduced by genome editing can lead to in-frame exon skipping. · 2017

     Not checked
279. 279.

     Schulte-Merker S, Stainier DY. Out with the old, in with the new: reassessing morpholino knockdowns in light of genome editing technology. Development. 2014;141(16):3103-3104.

     Not in our library10.1242/dev.112003

280. 280.

     Wienholds E, Schulte-Merker S, Walderich B, Plasterk RH. Target-selected inactivation of the zebrafish rag1 gene. Science. 2002;297(5578):99-102.

     Not in our library10.1126/science.1071762

281. 281.
     A rapid and effective method for screening, sequencing and reporter verification of engineered frameshift mutations in zebrafish · 2017

     Not checked
282. 282.

     Varshney GK, Pei W, LaFave MC, Idol J, Xu L, Gallardo V, Carrington B, Bishop K, Jones M, Li M, Harper U, Huang SC, Prakash A, Chen W, Sood R, Ledin J, Burgess SM. High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9. Genome Res. 2015;25(7):1030-1042.

     Not in our library10.1101/gr.186379.114

283. 283.

     Zhang Y, Huang H, Zhang B, Lin S. TALEN- and CRISPR-enhanced DNA homologous recombination for gene editing in zebrafish. Methods Cell Biol. 2016;135:107-120.

     Not in our library10.1016/bs.mcb.2016.03.005

284. 284.

     Meng X, Noyes MB, Zhu LJ, Lawson ND, Wolfe SA. Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases. Nat Biotechnol. 2008;26(6):695-701.

     Not in our library10.1038/nbt1398

285. 285.

     Villefranc JA, Amigo J, Lawson ND. Gateway compatible vectors for analysis of gene function in the zebrafish. Dev Dyn. 2007;236(11):3077-3087.

     Not in our library10.1002/dvdy.21354

286. 286.

     Blackburn PR, Campbell JM, Clark KJ, Ekker SC. The CRISPR system—keeping zebrafish gene targeting fresh. Zebrafish. 2013;10(1):116-118.

     Not in our library10.1089/zeb.2013.9999

287. 287.

     Chang N, Sun C, Gao L, Zhu D, Xu X, Zhu X, Xiong JW, Xi JJ. Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos. Cell Res. 2013;23(4):465-472.

     Not in our library10.1038/cr.2013.45

288. 288.

     Hruscha A, Krawitz P, Rechenberg A, Heinrich V, Hecht J, Haass C, Schmid B. Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish. Development. 2013;140(24):4982-4987.

     Not in our library10.1242/dev.099085

289. 289.
     Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System · 2013

     No notice
290. 290.

     Hwang WY, Fu Y, Reyon D, Maeder ML, Tsai SQ, Sander JD, Peterson RT, Yeh JR, Joung JK. Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat Biotechnol. 2013;31(3):227-229.

     Not in our library10.1038/nbt.2501

291. 291.

     Jao LE, Wente SR, Chen W. Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system. Proc Natl Acad Sci USA. 2013;110(34):13904-13909.

     Not in our library10.1073/pnas.1308335110

292. 292.

     Auer TO, Del Bene F. CRISPR/Cas9 and TALEN-mediated knock-in approaches in zebrafish. Methods. 2014;69(2):142-150.

     Not in our library10.1016/j.ymeth.2014.03.027

293. 293.

     Reade A, Motta-Mena LB, Gardner KH, Stainier DY, Weiner OD, Woo S. TAEL: a zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control. Development. 2017;144(2):345-355.

     Not in our library10.1242/dev.139238

294. 294.

     Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF. Stages of embryonic development of the zebrafish. Dev Dyn. 1995;203(3):253-310.

     Not in our library10.1002/aja.1002030302

295. 295.

     Butler D. Wellcome Trust funds bid to unravel zebrafish genome. Nature. 2000;408(6812):503.

     Not in our library10.1038/35046231

296. 296.

     Westerfield M. The Zebrafish book. 1995.

     Not in our library

297. 297.

     Weinstein BM, Fishman MC. Cardiovascular morphogenesis in zebrafish. Cardiovasc Res. 1996;31:E17-E24.

     Not in our library

298. 298.

     Weinstein BM, Schier AF, Abdelilah S, Malicki J, Solnica-Krezel L, Stemple DL, Stainier DY, Zwartkruis F, Driever W, Fishman MC. Hematopoietic mutations in the zebrafish. Development. 1996;123:303-309.

     Not in our library10.1242/dev.123.1.303

299. 299.

     Mullins MC, Hammerschmidt M, Haffter P, Nusslein-Volhard C. Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate. Curr Biol. 1994;4(3):189-202.

     Not in our library10.1016/s0960-9822(00)00048-8

300. 300.

     Driever W, Solnica-Krezel L, Schier AF, Neuhauss SC, Malicki J, Stemple DL, Stainier DY, Zwartkruis F, Abdelilah S, Rangini Z, Belak J, Boggs C. A genetic screen for mutations affecting embryogenesis in zebrafish. Development. 1996;123:37-46.

     Not in our library10.1242/dev.123.1.37

301. 301.

     Stainier DY, Fouquet B, Chen JN, Warren KS, Weinstein BM, Meiler SE, Mohideen MA, Neuhauss SC, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Driever W, Fishman MC. Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development. 1996;123:285-292.

     Not in our library10.1242/dev.123.1.285

302. 302.

     Lawson ND, Scheer N, Pham VN, Kim CH, Chitnis AB, Campos-Ortega JA, Weinstein BM. Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development. 2001;128(19):3675-3683.

     Not in our library10.1242/dev.128.19.3675

303. 303.

     Roman BL, Pham VN, Lawson ND, Kulik M, Childs S, Lekven AC, Garrity DM, Moon RT, Fishman MC, Lechleider RJ, Weinstein BM. Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development. 2002;129(12):3009-3019.

     Not in our library10.1242/dev.129.12.3009

304. 304.

     Lawson ND, Mugford JW, Diamond BA, Weinstein BM. Phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development. Genes Dev. 2003;17(11):1346-1351.

     Not in our library10.1101/gad.1072203

305. 305.

     Torres-Vazquez J, Gitler AD, Fraser SD, Berk JD, Van NP, Fishman MC, Childs S, Epstein JA, Weinstein BM. Semaphorin-plexin signaling guides patterning of the developing vasculature. Dev Cell. 2004;7(1):117-123.

     Not in our library10.1016/j.devcel.2004.06.008

306. 306.

     Shaw KM, Castranova DA, Pham VN, Kamei M, Kidd KR, Lo BD, Torres-Vasquez J, Ruby A, Weinstein BM. Fused-somites-like mutants exhibit defects in trunk vessel patterning. Dev Dyn. 2006;235(7):1753-1760.

     Not in our library10.1002/dvdy.20814

307. 307.

     Pham VN, Lawson ND, Mugford JW, Dye L, Castranova D, Lo B, Weinstein BM. Combinatorial function of ETS transcription factors in the developing vasculature. Dev Biol. 2007;303(2):772-783.

     Not in our library10.1016/j.ydbio.2006.10.030

308. 308.

     Gore AV, Swift MR, Cha YR, Lo B, McKinney MC, Li W, Castranova D, Davis A, Mukouyama YS, Weinstein BM. Rspo1/Wnt signaling promotes angiogenesis via Vegfc/Vegfr3. Development. 2011;138(22):4875-4886.

     Not in our library10.1242/dev.068460

309. 309.

     Pan W, Pham VN, Stratman AN, Castranova D, Kamei M, Kidd KR, Lo BD, Shaw KM, Torres-Vazquez J, Mikelis CM, Gutkind JS, Davis GE, Weinstein BM. CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis. Blood. 2012;120(2):489-498.

     Not in our library10.1182/blood-2012-02-408328

310. 310.

     Moens CB, Donn TM, Wolf-Saxon ER, Ma TP. Reverse genetics in zebrafish by TILLING. Brief Funct Genom Proteom. 2008;7(6):454-459.

     Not in our library10.1093/bfgp/eln046

311. 311.

     Varshney GK, Carrington B, Pei W, Bishop K, Chen Z, Fan C, Xu L, Jones M, LaFave MC, Ledin J, Sood R, Burgess SM. A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish. Nat Protoc. 2016;11(12):2357-2375.

     Not in our library10.1038/nprot.2016.141

312. 312.

     Won M, Ro H, Dawid IB. Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas. Proc Natl Acad Sci USA. 2015;112(40):12426-12431.

     Not in our library10.1073/pnas.1517033112

313. 313.

     Cha YR, Weinstein BM. Use of PCR template-derived probes prevents off-target whole mount in situ hybridization in transgenic zebrafish. Zebrafish. 2012;9(2):85-89.

     Not in our library10.1089/zeb.2011.0731

314. 314.

     Hogan BM, Bos FL, Bussmann J, Witte M, Chi NC, Duckers HJ, Schulte-Merker S. Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting. Nat Genet. 2009;41(4):396-398.

     Not in our library10.1038/ng.321

315. 315.

     Le Guen L, Karpanen T, Schulte D, Harris NC, Koltowska K, Roukens G, Bower NI, van Impel A, Stacker SA, Achen MG, Schulte-Merker S, Hogan BM. Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis. Development. 2014;141(6):1239-1249.

     Not in our library10.1242/dev.100495

316. 316.

     Villefranc JA, Nicoli S, Bentley K, Jeltsch M, Zarkada G, Moore JC, Gerhardt H, Alitalo K, Lawson ND. A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development. Development. 2013;140(7):1497-1506.

     Not in our library10.1242/dev.084152

317. 317.

     Yaniv K, Isogai S, Castranova D, Dye L, Hitomi J, Weinstein BM. Live imaging of lymphatic development in the zebrafish. Nat Med. 2006;12(6):711-716.

     Not in our library10.1038/nm1427

318. 318.

     Isogai S, Hitomi J, Yaniv K, Weinstein BM. Zebrafish as a new animal model to study lymphangiogenesis. Anat Sci Int. 2009;84(3):102-111.

     Not in our library10.1007/s12565-009-0024-3

319. 319.
     A novel perivascular cell population in the zebrafish brain · 2017

     Not checked
320. 320.

     Jung HM, Castranova D, Swift MR, Pham VN, Venero Galanternik MV, Isogai S, Butler MG, Mulligan TS, Weinstein BM. Development of the larval lymphatic system in the zebrafish. Development. 2017.

     Not in our library10.1242/dev.145755

321. 321.

     Poelma C, Kloosterman A, Hierck BP, Westerweel J. Accurate blood flow measurements: are artificial tracers necessary? PLoS ONE. 2012;7(9):e45247.

     Not in our library10.1371/journal.pone.0045247

322. 322.

     Vennemann P, Kiger KT, Lindken R, Groenendijk BC, Stekelenburg-de Vos S, ten Hagen TL, Ursem NT, Poelmann RE, Westerweel J, Hierck BP. In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart. J Biomech. 2006;39(7):1191-1200.

     Not in our library10.1016/j.jbiomech.2005.03.015

323. 323.

     Zhou J, Zhang H, Wang H, Lutz AM, El Kaffas A, Tian L, Hristov D, Willmann JK. Early prediction of tumor response to bevacizumab treatment in murine colon cancer models using three-dimensional dynamic contrast-enhanced ultrasound imaging. Angiogenesis. 2017;20(4):547-555.

     Not in our library10.1007/s10456-017-9566-5

324. 324.

     Kwan KM, Fujimoto E, Grabher C, Mangum BD, Hardy ME, Campbell DS, Parant JM, Yost HJ, Kanki JP, Chien CB. The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs. Dev Dyn. 2007;236(11):3088-3099.

     Not in our library10.1002/dvdy.21343

325. 325.
     zTrap: zebrafish gene trap and enhancer trap database · 2010

     No notice
326. 326.

     Zhang Y, Werling U, Edelmann W. SLiCE: a novel bacterial cell extract-based DNA cloning method. Nucleic Acids Res. 2012;40(8):e55.

     Not in our library10.1093/nar/gkr1288

327. 327.

     Kamei M, Isogai S, Pan W, Weinstein BM. Imaging blood vessels in the zebrafish. Methods Cell Biol. 2010;100:27-54.

     Not in our library10.1016/b978-0-12-384892-5.00002-5

328. 328.

     Isogai S, Horiguchi M, Weinstein BM. The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. Dev Biol. 2001;230(2):278-301.

     Not in our library10.1006/dbio.2000.9995

329. 329.

     Lawson ND, Weinstein BM. In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev Biol. 2002;248(2):307-318.

     Not in our library10.1006/dbio.2002.0711

330. 330.

     Stratman AN, Pezoa SA, Farrelly OM, Castranova D, Dye LE, Butler MG, Sidik H, Talbot WS, Weinstein BM. Interactions between mural cells and endothelial cells stabilize the developing zebrafish dorsal aorta. Development. 2017;144(1):115-127.

     Not in our library10.1242/dev.143131

331. 331.

     Choi WY, Gemberling M, Wang J, Holdway JE, Shen MC, Karlstrom RO, Poss KD. In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration. Development. 2013;140(3):660-666.

     Not in our library10.1242/dev.088526

332. 332.

     Jung HM, Isogai S, Kamei M, Castranova D, Gore AV, Weinstein BM. Imaging blood vessels and lymphatic vessels in the zebrafish. Methods Cell Biol. 2016;133:69-103.

     Not in our library10.1016/bs.mcb.2016.03.023

333. 333.

     van Rooijen E, Voest EE, Logister I, Bussmann J, Korving J, van Eeden FJ, Giles RH, Schulte-Merker S. von Hippel–Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish. Dis Model Mech. 2010;3(5–6):343-353.

     Not in our library10.1242/dmm.004036

334. 334.

     Rous P, Murphy JB. Tumor implantations in the developing embryo. J Am Med Assoc. 1911;56:741.

     Not in our library

335. 335.

     Nowak-Sliwinska P, Segura T, Iruela-Arispe ML. The chicken chorioallantoic membrane model in biology, medicine and bioengineering. Angiogenesis. 2014;17(4):779-804.

     Not in our library10.1007/s10456-014-9440-7

336. 336.

     Ribatti D, Nico B, Vacca A, Roncali L, Burri PH, Djonov V. Chorioallantoic membrane capillary bed: a useful target for studying angiogenesis and anti-angiogenesis in vivo. Anat Rec. 2001;264(4):317-324.

     Not in our library10.1002/ar.10021

337. 337.

     Ribatti D, Vacca A, Roncali L, Dammacco F. The chick embryo chorioallantoic membrane as a model for in vivo research on anti-angiogenesis. Curr Pharm Biotechnol. 2000;1(1):73-82.

     Not in our library10.2174/1389201003379040

338. 338.

     Adar Y, Stark M, Bram EE, Nowak-Sliwinska P, van den Bergh H, Szewczyk G, Sarna T, Skladanowski A, Griffioen AW, Assaraf YG. Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers. Cell Death Dis. 2012;3:1-10.

     Not in our library10.1038/cddis.2012.30

339. 339.

     Valdes TI, Klueh U, Kreutzer D, Moussy F. Ex ova chick chorioallantoic membrane as a novel in vivo model for testing biosensors. J Biomed Mater Res Part A. 2003;67(1):215-223.

     Not in our library10.1002/jbm.a.10055

340. 340.

     Valdes TI, Kreutzer D, Moussy F. The chick chorioallantoic membrane as a novel in vivo model for the testing of biomaterials. J Biomed Mater Res. 2002;62(2):273-282.

     Not in our library10.1002/jbm.10152

341. 341.

     Weiss A, Bonvin D, Berndsen RH, Scherrer E, Wong TJ, Dyson PJ, Griffioen AW, Nowak-Sliwinska P. Angiostatic treatment prior to chemo- or photodynamic therapy improves anti-tumor efficacy. Sci Rep. 2015;5:8990.

     Not in our library10.1038/srep08990

342. 342.

     Lim SH, Nowak-Sliwinska P, Kamarulzaman FA, van den Bergh H, Wagnieres G, Lee HB. The neovessel occlusion efficacy of 15-hydroxypurpurin-7-lactone dimethyl ester induced with photodynamic therapy. Photochem Photobiol. 2010;86(2):397-402.

     Not in our library10.1111/j.1751-1097.2009.00684.x

343. 343.

     Brauer R, Chen P. Influenza virus propagation in embryonated chicken eggs. J Vis Exp. 2015.

     Not in our library10.3791/52421

344. 344.

     Hamburger V, Hamilton H. A series of normal stages in the development of the chick embryo. J Morphol. 1951;88:49-92.

     Not in our library

345. 345.

     Kilarski WW, Samolov B, Petersson L, Kvanta A, Gerwins P. Biomechanical regulation of blood vessel growth during tissue vascularization. Nat Med. 2009;15(6):657-664.

     Not in our library10.1038/nm.1985

346. 346.

     Jakob W, Jentzsch KD, Mauersberger B, Heder G. The chick embryo choriallantoic membrane as a bioassay for angiogenesis factors: reactions induced by carrier materials. Exp Pathol. 1978;15(5):241-249.

     Not in our library10.1016/s0014-4908(78)80064-7

347. 347.

     Ribatti D. The chick embryo chorioallantoic membrane in the study of angiogenesis and metastasis. 2010.

     Not in our library

348. 348.

     Tufan AC, Satiroglu-Tufan NL. The chick embryo chorioallantoic membrane as a model system for the study of tumor angiogenesis, invasion and development of anti-angiogenic agents. Curr Cancer Drug Targets. 2005;5(4):249-266.

     Not in our library10.2174/1568009054064624

349. 349.

     West DC, Thompson WD, Sells PG, Burbridge MF. Angiogenesis assays using chick chorioallantoic membrane. Methods Mol Med. 2001;46:107-129.

     Not in our library10.1385/1-59259-143-4:107

350. 350.

     Nakao S, Maghadam AH, Martin SG, Hewett PW. Chorioallantoic membrane microtumor model to study the mechanisms of tumor angiogenesis, vascular permeability, and tumor cell intravasion. Angiogenesis protocols. 2016;283-298.

     Not in our library10.1007/978-1-4939-3628-1_19

351. 351.

     Auerbach R, Lewis R, Shinners B, Kubai L, Akhtar N. Angiogenesis assays: a critical overview. Clin Chem. 2003;49(1):32-40.

     Not in our library10.1373/49.1.32

352. 352.

     Auerbach R, Kubai L, Knighton D, Folkman J. A simple procedure for the long-term cultivation of chicken embryos. Dev Biol. 1974;41(2):391-394.

     Not in our library10.1016/0012-1606(74)90316-9

353. 353.

     Dohle DS, Pasa SD, Gustmann S, Laub M, Wissler JH, Jennissen HP, Dunker N. Chick ex ovo culture and ex ovo CAM assay: how it really works. J Vis Exp. 2009.

     Not in our library10.3791/1620

354. 354.

     Huang W, Itayama M, Arai F, Furukawa KS, Ushida T, Kawahara T. An angiogenesis platform using a cubic artificial eggshell with patterned blood vessels on chicken chorioallantoic membrane. PLoS ONE. 2017;12(4):e0175595.

     Not in our library10.1371/journal.pone.0175595

355. 355.

     Nowak-Sliwinska P, Ballini JP, Wagnieres G, van den Bergh H. Processing of fluorescence angiograms for the quantification of vascular effects induced by anti-angiogenic agents in the CAM model. Microvasc Res. 2010;79(1):21-28.

     Not in our library10.1016/j.mvr.2009.10.004

356. 356.

     Nguyen M, Shing Y, Folkman J. Quantitation of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane. Microvasc Res. 1994;47(1):31-40.

     Not in our library10.1006/mvre.1994.1003

357. 357.

     Cimpean AM, Seclaman E, Ceausu R, Gaje P, Feflea S, Anghel A, Raica M, Ribatti D. VEGF-A/HGF induce Prox-1 expression in the chick embryo chorioallantoic membrane lymphatic vasculature. Clin Exp Med. 2010;10(3):169-172.

     Not in our library10.1007/s10238-009-0085-6

358. 358.

     Clavel CM, Paunescu E, Nowak-Sliwinska P, Griffioen AW, Scopelliti R, Dyson PJ. Discovery of a highly tumor-selective organometallic ruthenium(II)-arene complex. J Med Chem. 2014;57(8):3546-3558.

     Not in our library10.1021/jm5002748

359. 359.

     Nowak-Sliwinska P, Wagnieres G, van den Bergh H, Griffioen AW. Angiostasis-induced vascular normalization can improve photodynamic therapy. Cell Mol Life Sci. 2010;67(9):1559-1560.

     Not in our library10.1007/s00018-010-0294-x

360. 360.

     Kilarski WW, Petersson L, Fuchs PF, Zielinski MS, Gerwins P. An in vivo neovascularization assay for screening regulators of angiogenesis and assessing their effects on pre-existing vessels. Angiogenesis. 2012;15(4):643-655.

     Not in our library10.1007/s10456-012-9287-8

361. 361.

     Weiss A, van Beijnum JR, Bonvin D, Jichlinski P, Dyson PJ, Griffioen AW, Nowak-Sliwinska P. Low-dose angiostatic tyrosine kinase inhibitors improve photodynamic therapy for cancer: lack of vascular normalization. J Cell Mol Med. 2014;18:480-491.

     Not in our library10.1111/jcmm.12199

362. 362.

     Hagedorn M, Javerzat S, Gilges D, Meyre A, de Lafarge B, Eichmann A, Bikfalvi A. Accessing key steps of human tumor progression in vivo by using an avian embryo model. Proc Natl Acad Sci USA. 2005;102(5):1643-1648.

     Not in our library10.1073/pnas.0408622102

363. 363.

     Dumartin L, Quemener C, Laklai H, Herbert J, Bicknell R, Bousquet C, Pyronnet S, Castronovo V, Schilling MK, Bikfalvi A, Hagedorn M. Netrin-1 mediates early events in pancreatic adenocarcinoma progression, acting on tumor and endothelial cells. Gastroenterology. 2010.

     Not in our library10.1053/j.gastro.2009.12.061

364. 364.

     Palmer TD, Lewis J, Zijlstra A. Quantitative analysis of cancer metastasis using an avian embryo model. J Vis Exp. 2011.

     Not in our library10.3791/2815

365. 365.

     Herbert JM, Stekel DJ, Mura M, Sychev M, Bicknell R. Bioinformatic methods for finding differentially expressed genes in cDNA libraries, applied to the identification of tumour vascular targets. Methods Mol Biol. 2011;729:99-119.

     Not in our library10.1007/978-1-61779-065-2_7

366. 366.

     Soulet F, Kilarski WW, Roux-Dalvai F, Herbert JM, Sacewicz I, Mouton-Barbosa E, Bicknell R, Lalor P, Monsarrat B, Bikfalvi A. Mapping the extracellular and membrane proteome associated with the vasculature and the stroma in the embryo. Mol Cell Proteom MCP. 2013;12(8):2293-2312.

     Not in our library10.1074/mcp.m112.024075

367. 367.

     Kilarski WW, Herbert J, Bikfalvi A. Methods for mapping the extracellular and membrane proteome in the avian embryo, and identification of putative vascular targets or endothelial genes. Methods Mol Biol. 2018;1722:31-56.

     Not in our library10.1007/978-1-4939-7553-2_3

368. 368.

     Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature. 2004;432(7018):695-716.

     Not in our library10.1038/nature03154

369. 369.

     Arora R, Papaioannou VE. The murine allantois: a model system for the study of blood vessel formation. Blood. 2012;120(13):2562-2572.

     Not in our library10.1182/blood-2012-03-390070

370. 370.

     Downs KM, Temkin R, Gifford S, McHugh J. Study of the murine allantois by allantoic explants. Dev Biol. 2001;233(2):347-364.

     Not in our library10.1006/dbio.2001.0227

371. 371.

     Crosby CV, Fleming PA, Argraves WS, Corada M, Zanetta L, Dejana E, Drake CJ. VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly. Blood. 2005;105(7):2771-2776.

     Not in our library10.1182/blood-2004-06-2244

372. 372.

     Perryn ED, Czirok A, Little CD. Vascular sprout formation entails tissue deformations and VE-cadherin-dependent cell-autonomous motility. Dev Biol. 2008;313(2):545-555.

     Not in our library10.1016/j.ydbio.2007.10.036

373. 373.

     Winderlich M, Keller L, Cagna G, Broermann A, Kamenyeva O, Kiefer F, Deutsch U, Nottebaum AF, Vestweber D. VE-PTP controls blood vessel development by balancing Tie-2 activity. J Cell Biol. 2009;185(4):657-671.

     Not in our library10.1083/jcb.200811159

374. 374.

     Argraves KM, Wilkerson BA, Argraves WS. Sphingo-sine-1-phosphate signaling in vasculogenesis and angiogenesis. World J Biol Chem. 2010;1(10):291-297.

     Not in our library10.4331/wjbc.v1.i10.291

375. 375.

     Downs KM. In vitro methods for studying vascularization of the murine allantois and allantoic union with the chorion. Methods Mol Med. 2006;121:241-272.

     Not in our library10.1385/1-59259-983-4:239

376. 376.

     Downs KM, Gardner RL. An investigation into early placental ontogeny: allantoic attachment to the chorion is selective and developmentally regulated. Development. 1995;121(2):407-416.

     Not in our library10.1242/dev.121.2.407

377. 377.

     Gentile C, Fleming PA, Mironov V, Argraves KM, Argraves WS, Drake CJ. VEGF-mediated fusion in the generation of uniluminal vascular spheroids. Dev Dyn. 2008;237(10):2918-2925.

     Not in our library10.1002/dvdy.21720

378. 378.

     Arora R, del Alcazar CM, Morrisey EE, Naiche LA, Papaioannou VE. Candidate gene approach identifies multiple genes and signaling pathways downstream of Tbx4 in the developing allantois. PLoS ONE. 2012;7(8):e43581.

     Not in our library10.1371/journal.pone.0043581

379. 379.
     A Computational Tool for Quantitative Analysis of Vascular Networks · 2011

     No notice
380. 380.

     Gambardella L, Hemberger M, Hughes B, Zudaire E, Andrews S, Vermeren S. PI3 K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis. Sci Signal. 2010;3(145):ra76.

     Not in our library10.1126/scisignal.2001026

381. 381.

     Passaniti A, Taylor RM, Pili R, Guo Y, Long PV, Haney JA, Pauly RR, Grant DS, Martin GR. A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor. Lab Investig J Tech Methods Pathol. 1992;67(4):519-528.

     Not in our library

382. 382.

     Malinda KM. In vivo matrigel migration and angiogenesis assay. Methods Mol Biol. 2009;467:287-294.

     Not in our library10.1007/978-1-59745-241-0_17

383. 383.

     Norrby K. In vivo models of angiogenesis. J Cell Mol Med. 2006;10(3):588-612.

     Not in our library10.1111/j.1582-4934.2006.tb00423.x

384. 384.

     Kibbey MC, Corcoran MC, Wahl LM, Kleinman HK. Laminin SIKVAV peptide induced angiogeneses in vivo is potentiated by neutrophils. J Cell Physiol. 1994;160:185-193.

     Not in our library10.1002/jcp.1041600121

385. 385.

     Salcedo R, Ponce ML, Young HA, Wasserman K, Ward JM, Kleinman HK, Oppenheim JJ, Murphy WJ. Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood. 2000;96(1):34-40.

     Not in our library

386. 386.

     Johns A, Freay AD, Fraser W, Korach KS, Rubanyi GM. Disruption of estrogen receptor gene prevents 17 beta estradiol-induced angiogenesis in transgenic mice. Endocrinology. 1996;137(10):4511-4513.

     Not in our library10.1210/endo.137.10.8828515

387. 387.

     Ferber S, Tiram G, Satchi-Fainaro R. Monitoring functionality and morphology of vasculature recruited by factors secreted by fast-growing tumor-generating cells. J Vis Exp. 2014;93:e51525.

     Not in our library10.3791/51525

388. 388.

     Kleinman HK, Martin GR. Matrigel: basement membrane matrix with biological activity. Semin Cancer Biol. 2005;15(5):378-386.

     Not in our library10.1016/j.semcancer.2005.05.004

389. 389.

     Benton G, Arnaoutova I, George J, Kleinman HK, Koblinski J. Matrigel: from discovery and ECM mimicry to assays and models for cancer research. Adv Drug Deliv Rev. 2014;79–80:3-18.

     Not in our library10.1016/j.addr.2014.06.005

390. 390.

     Thijssen VL, Brandwijk RJ, Dings RP, Griffioen AW. Angiogenesis gene expression profiling in xenograft models to study cellular interactions. Exp Cell Res. 2004;299(2):286-293.

     Not in our library10.1016/j.yexcr.2004.06.014

391. 391.
     The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling · 2015

     No notice
392. 392.

     Guedez L, Rivera AM, Salloum R, Miller ML, Diegmueller JJ, Bungay PM, Stetler-Stevenson WG. Quantitative assessment of angiogenic responses by the directed in vivo angiogenesis assay. Am J Pathol. 2003;162(5):1431-1439.

     Not in our library10.1016/s0002-9440(10)64276-9

393. 393.

     Melero-Martin JM, Khan ZA, Picard A, Wu X, Paruchuri S, Bischoff J. In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood. 2007;109(11):4761-4768.

     Not in our library10.1182/blood-2006-12-062471

394. 394.

     Melero-Martin JM, De Obaldia ME, Kang SY, Khan ZA, Yuan L, Oettgen P, Bischoff J. Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ Res. 2008;103(2):194-202.

     Not in our library10.1161/circresaha.108.178590

395. 395.

     Allen P, Melero-Martin J, Bischoff J. Type I collagen, fibrin and PuraMatrix matrices provide permissive environments for human endothelial and mesenchymal progenitor cells to form neovascular networks. J Tissue Eng Regen Med. 2011;5(4):e74-e86.

     Not in our library10.1002/term.389

396. 396.

     Allen P, Kang KT, Bischoff J. Rapid onset of perfused blood vessels after implantation of ECFCs and MPCs in collagen, PuraMatrix and fibrin provisional matrices. J Tissue Eng Regen Med. 2013.

     Not in our library10.1002/term.1803

397. 397.

     Lin RZ, Moreno-Luna R, Munoz-Hernandez R, Li D, Jaminet SC, Greene AK, Melero-Martin JM. Human white adipose tissue vasculature contains endothelial colony-forming cells with robust in vivo vasculogenic potential. Angiogenesis. 2013;16(4):735-744.

     Not in our library10.1007/s10456-013-9350-0

398. 398.

     Samuel R, Daheron L, Liao S, Vardam T, Kamoun WS, Batista A, Buecker C, Schafer R, Han X, Au P, Scadden DT, Duda DG, Fukumura D, Jain RK. Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells. Proc Natl Acad Sci USA. 2013;110(31):12774-12779.

     Not in our library10.1073/pnas.1310675110

399. 399.

     Au P, Tam J, Fukumura D, Jain RK. Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. Blood. 2008;111(9):4551-4558.

     Not in our library10.1182/blood-2007-10-118273

400. 400.

     Traktuev DO, Prater DN, Merfeld-Clauss S, Sanjeevaiah AR, Saadatzadeh MR, Murphy M, Johnstone BH, Ingram DA, March KL. Robust functional vascular network formation in vivo by cooperation of adipose progenitor and endothelial cells. Circ Res. 2009;104(12):1410-1420.

     Not in our library10.1161/circresaha.108.190926

401. 401.

     Chen X, Aledia AS, Ghajar CM, Griffith CK, Putnam AJ, Hughes CC, George SC. Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature. Tissue Eng. 2009;15(6):1363-1371.

     Not in our library10.1089/ten.tea.2008.0314

402. 402.

     Lin RZ, Moreno-Luna R, Zhou B, Pu WT, Melero-Martin JM. Equal modulation of endothelial cell function by four distinct tissue-specific mesenchymal stem cells. Angiogenesis. 2012;15(3):443-455.

     Not in our library10.1007/s10456-012-9272-2

403. 403.

     Au P, Daheron LM, Duda DG, Cohen KS, Tyrrell JA, Lanning RM, Fukumura D, Scadden DT, Jain RK. Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. Blood. 2008;111(3):1302-1305.

     Not in our library10.1182/blood-2007-06-094318

404. 404.

     Chen YC, Lin RZ, Qi H, Yang Y, Bae H, Melero-Martin JM, Khademhosseini A. Functional human vascular network generated in photocrosslinkable gelatin methacrylate hydrogels. Adv Funct Mater. 2012;22(10):2027-2039.

     Not in our library10.1002/adfm.201101662

405. 405.
     In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse · 2000

     Not checked
406. 406.

     Enis DR, Shepherd BR, Wang Y, Qasim A, Shanahan CM, Weissberg PL, Kashgarian M, Pober JS, Schechner JS. Induction, differentiation, and remodeling of blood vessels after transplantation of Bcl-2-transduced endothelial cells. Proc Natl Acad Sci USA. 2005;102(2):425-430.

     Not in our library10.1073/pnas.0408357102

407. 407.

     Koike N, Fukumura D, Gralla O, Au P, Schechner JS, Jain RK. Tissue engineering: creation of long-lasting blood vessels. Nature. 2004;428(6979):138-139.

     Not in our library10.1038/428138a

408. 408.

     Lin RZ, Melero-Martin JM. Fibroblast growth factor-2 facilitates rapid anastomosis formation between bioengineered human vascular networks and living vasculature. Methods. 2012;56(3):440-451.

     Not in our library10.1016/j.ymeth.2012.01.006

409. 409.

     Lin RZ, Melero-Martin JM. Bioengineering human micro-vascular networks in immunodeficient mice. J Vis Exp. 2011;53:e3065.

     Not in our library10.3791/3065

410. 410.

     Kang KT, Allen P, Bischoff J. Bioengineered human vascular networks transplanted into secondary mice reconnect with the host vasculature and re-establish perfusion. Blood. 2011;118(25):6718-6721.

     Not in our library10.1182/blood-2011-08-375188

411. 411.
     Endothelial colony forming cells and mesenchymal progenitor cells form blood vessels and increase blood flow in ischemic muscle · 2017

     Not checked
412. 412.

     Kang K-T, Coggins M, Xiao C, Rosenzweig A, Bischoff J. Human vasculogenic cells form functional blood vessels and mitigate adverse remodeling after ischemia reperfusion injury in rats. Angiogenesis. 2013;16(4):773-784.

     Not in our library10.1007/s10456-013-9354-9

413. 413.

     Greenberger S, Boscolo E, Adini I, Mulliken JB, Bischoff J. Corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells. N Engl J Med. 2010;362(11):1005-1013.

     Not in our library10.1056/nejmoa0903036

414. 414.

     Greenberger S, Yuan S, Walsh LA, Boscolo E, Kang KT, Matthews B, Mulliken JB, Bischoff J. Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma. J Invest Dermatol. 2011;131(12):2467-2476.

     Not in our library10.1038/jid.2011.300

415. 415.

     Boscolo E, Limaye N, Huang L, Kang KT, Soblet J, Uebelhoer M, Mendola A, Natynki M, Seront E, Dupont S, Hammer J, Legrand C, Brugnara C, Eklund L, Vikkula M, Bischoff J, Boon LM. Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects. J Clin Investig. 2015;125(9):3491-3504.

     Not in our library10.1172/jci76004

416. 416.

     Lin RZ, Dreyzin A, Aamodt K, Li D, Jaminet SC, Dudley AC, Melero-Martin JM. Induction of erythropoiesis using human vascular networks genetically engineered for controlled erythropoietin release. Blood. 2011;118(20):5420-5428.

     Not in our library10.1182/blood-2011-08-372946

417. 417.

     Bichsel CA, Hall SR, Schmid RA, Guenat OT, Geiser T. Primary human lung pericytes support and stabilize in vitro perfusable microvessels. Tissue Eng. 2015;21(15–16):2166-2176.

     Not in our library10.1089/ten.tea.2014.0545

418. 418.

     Tual-Chalot S, Allinson KR, Fruttiger M, Arthur HM. Whole mount immunofluorescent staining of the neonatal mouse retina to investigate angiogenesis in vivo. J Vis Exp. 2013;77:e50546.

     Not in our library10.3791/50546

419. 419.

     Powner MB, Vevis K, McKenzie JA, Gandhi P, Jadeja S, Fruttiger M. Visualization of gene expression in whole mouse retina by in situ hybridization. Nat Protoc. 2012;7(6):1086-1096.

     Not in our library10.1038/nprot.2012.050

420. 420.

     Gerhardt H, Golding M, Fruttiger M, Ruhrberg C, Lundkvist A, Abramsson A, Jeltsch M, Mitchell C, Alitalo K, Shima D, Betsholtz C. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol. 2003;161(6):1163-1177.

     Not in our library10.1083/jcb.200302047

421. 421.

     del Toro R, Prahst C, Mathivet T, Siegfried G, Kaminker JS, Larrivee B, Breant C, Duarte A, Takakura N, Fukamizu A, Penninger J, Eichmann A. Identification and functional analysis of endothelial tip cell-enriched genes. Blood. 2010;116(19):4025-4033.

     Not in our library10.1182/blood-2010-02-270819

422. 422.

     Siemerink MJ, Klaassen I, Vogels IM, Griffioen AW, Van Noorden CJ, Schlingemann RO. CD34 marks angiogenic tip cells in human vascular endothelial cell cultures. Angiogenesis. 2012;15(1):151-163.

     Not in our library10.1007/s10456-011-9251-z

423. 423.

     Pitulescu ME, Schmidt I, Giaimo BD, Antoine T, Berkenfeld F, Ferrante F, Park H, Ehling M, Biljes D, Rocha SF, Langen UH, Stehling M, Nagasawa T, Ferrara N, Borggrefe T, Adams RH. Dll4 and Notch signalling couples sprouting angiogenesis and artery formation. Nat Cell Biol. 2017;19(8):915-927.

     Not in our library10.1038/ncb3555

424. 424.

     Hellstrom M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalen M, Gerhardt H, Betsholtz C. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 2007;445(7129):776-780.

     Not in our library10.1038/nature05571

425. 425.
     VEGF-A/Notch-Induced Podosomes Proteolyse Basement Membrane Collagen-IV during Retinal Sprouting Angiogenesis · 2016

     Not checked
426. 426.

     Fraccaroli A, Franco CA, Rognoni E, Neto F, Rehberg M, Aszodi A, Wedlich-Soldner R, Pohl U, Gerhardt H, Montanez E. Visualization of endothelial actin cytoskeleton in the mouse retina. PLoS ONE. 2012;7(10):e47488.

     Not in our library10.1371/journal.pone.0047488

427. 427.

     Jakobsson L, Franco CA, Bentley K, Collins RT, Ponsioen B, Aspalter IM, Rosewell I, Busse M, Thurston G, Medvinsky A, Schulte-Merker S, Gerhardt H. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat Cell Biol. 2010;12(10):943-953.

     Not in our library10.1038/ncb2103

428. 428.
     Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch · 2015

     No notice
429. 429.

     Schlingemann RO, Rietveld FJ, de Waal RM, Bradley NJ, Skene AI, Davies AJ, Greaves MF, Denekamp J, Ruiter DJ. Leukocyte antigen CD34 is expressed by a subset of cultured endothelial cells and on endothelial abluminal microprocesses in the tumor stroma. Lab Investig J Tech Methods Pathol. 1990;62(6):690-696.

     Not in our library

430. 430.

     Fantin A, Lampropoulou A, Gestri G, Raimondi C, Senatore V, Zachary I, Ruhrberg C. NRP1 Regulates CDC42 activation to promote filopodia formation in endothelial tip cells. Cell Rep. 2015;11(10):1577-1590.

     Not in our library10.1016/j.celrep.2015.05.018

431. 431.
     Astrocyte-Derived Vascular Endothelial Growth Factor Stabilizes Vessels in the Developing Retinal Vasculature · 2010

     No notice
432. 432.

     Gimbrone MA, Leapman SB, Cotran RS, Folkman J. Tumor angiogenesis: iris neovascularization at a distance from experimental intraocular tumors. J Natl Cancer Inst. 1973;50(1):219-228.

     Not in our library10.1093/jnci/50.1.219

433. 433.

     Muthukkaruppan V, Auerbach R. Angiogenesis in the mouse cornea. Science. 1979;205(4413):1416-1418.

     Not in our library10.1126/science.472760

434. 434.

     Polverini PJ, Leibovich SJ. Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages. Lab Investig J Tech Methods Pathol. 1984;51(6):635-642.

     Not in our library

435. 435.

     Rogers MS, Birsner AE, D’Amato RJ. The mouse cornea micropocket angiogenesis assay. Nat Protoc. 2007;2(10):2545-2550.

     Not in our library10.1038/nprot.2007.368

436. 436.

     Morbidelli L, Ziche M. The rabbit corneal pocket assay. Methods Mol Biol. 2016;1430:299-310.

     Not in our library10.1007/978-1-4939-3628-1_20

437. 437.

     Chang LK, Garcia-Cardena G, Farnebo F, Fannon M, Chen EJ, Butterfield C, Moses MA, Mulligan RC, Folkman J, Kaipainen A. Dose-dependent response of FGF-2 for lymphangiogenesis. Proc Natl Acad Sci USA. 2004;101(32):11658-11663.

     Not in our library10.1073/pnas.0404272101

438. 438.

     Kenyon BM, Voest EE, Chen CC, Flynn E, Folkman J, D’Amato RJ. A model of angiogenesis in the mouse cornea. Invest Ophthalmol Vis Sci. 1996;37(8):1625-1632.

     Not in our library

439. 439.

     Bussolino F, Di Renzo MF, Ziche M, Bocchietto E, Olivero M, Naldini L, Gaudino G, Tamagnone L, Coffer A, Comoglio PM. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol. 1992;119(3):629-641.

     Not in our library10.1083/jcb.119.3.629

440. 440.

     Ziche M, Morbidelli L, Choudhuri R, Zhang HT, Donnini S, Granger HJ, Bicknell R. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis. J Clin Invest. 1997;99(11):2625-2634.

     Not in our library10.1172/jci119451

441. 441.

     Birsner AE, Benny O, D’Amato RJ. The corneal micropocket assay: a model of angiogenesis in the mouse eye. J Vis Exp. 2014.

     Not in our library10.3791/51375

442. 442.

     Schwartz S, George J, Ben-Shoshan J, Luboshits G, Avni I, Levkovitch-Verbin H, Ziv H, Rosner M, Barak A. Drug modification of angiogenesis in a rat cornea model. Invest Ophthalmol Vis Sci. 2008;49(1):250-254.

     Not in our library10.1167/iovs.06-1337

443. 443.

     Laude A, Cackett PD, Vithana EN, Yeo IY, Wong D, Koh AH, Wong TY, Aung T. Polypoidal choroidal vasculopathy and neovascular age-related macular degeneration: same or different disease? Prog Retinal Eye Res. 2010;29(1):19-29.

     Not in our library10.1016/j.preteyeres.2009.10.001

444. 444.

     Nowak-Sliwinska P, Sickenberg M, van den Bergh H, Koh AHC. Photodynamic therapy for polypoidal choroidal vasculopathy. Prog Eye Retinal Res. 2013;37:182-199.

     Not in our library10.1016/j.preteyeres.2013.09.003

445. 445.

     Hartnett ME. Pathophysiology and mechanisms of severe retinopathy of prematurity. Ophthalmology. 2015;122(1):200-210.

     Not in our library10.1016/j.ophtha.2014.07.050

446. 446.

     Smith LE, Wesolowski E, McLellan A, Kostyk SK, D’Amato R, Sullivan R, D’Amore PA. Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci. 1994;35(1):101-111.

     Not in our library

447. 447.

     Otani A, Slike BM, Dorrell MI, Hood J, Kinder K, Ewalt KL, Cheresh D, Schimmel P, Friedlander M. A fragment of human TrpRS as a potent antagonist of ocular angiogenesis. Proc Natl Acad Sci USA. 2002;99(1):178-183.

     Not in our library10.1073/pnas.012601899

448. 448.

     Ritter MR, Aguilar E, Banin E, Scheppke L, Uusitalo-Jarvinen H, Friedlander M. Three-dimensional in vivo imaging of the mouse intraocular vasculature during development and disease. Invest Ophthalmol Vis Sci. 2005;46(9):3021-3026.

     Not in our library10.1167/iovs.05-0153

449. 449.

     Stahl A, Connor KM, Sapieha P, Willett KL, Krah NM, Dennison RJ, Chen J, Guerin KI, Smith LE. Computer-aided quantification of retinal neovascularization. Angiogenesis. 2009;12(3):297-301.

     Not in our library10.1007/s10456-009-9155-3

450. 450.

     Wangsa-Wirawan ND, Linsenmeier RA. Retinal oxygen: fundamental and clinical aspects. Arch Ophthalmol. 2003;121(4):547-557.

     Not in our library10.1001/archopht.121.4.547

451. 451.

     Gu X, Samuel S, El-Shabrawey M, Caldwell RB, Bartoli M, Marcus DM, Brooks SE. Effects of sustained hyperoxia on revascularization in experimental retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2002;43(2):496-502.

     Not in our library

452. 452.

     Chen J, Connor KM, Aderman CM, Willett KL, Aspegren OP, Smith LE. Suppression of retinal neovascularization by erythropoietin siRNA in a mouse model of proliferative retinopathy. Invest Ophthalmol Vis Sci. 2009;50(3):1329-1335.

     Not in our library10.1167/iovs.08-2521

453. 453.

     Pierce EA, Avery RL, Foley ED, Aiello LP, Smith LE. Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci USA. 1995;92(3):905-909.

     Not in our library10.1073/pnas.92.3.905

454. 454.

     Ozaki H, Yu AY, Della N, Ozaki K, Luna JD, Yamada H, Hackett SF, Okamoto N, Zack DJ, Semenza GL, Campochiaro PA. Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression. Invest Ophthalmol Vis Sci. 1999;40(1):182-189.

     Not in our library

455. 455.

     Smith LE, Shen W, Perruzzi C, Soker S, Kinose F, Xu X, Robinson G, Driver S, Bischoff J, Zhang B, Schaeffer JM, Senger DR. Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor. Nat Med. 1999;5(12):1390-1395.

     Not in our library10.1038/70963

456. 456.

     Connor KM, Krah NM, Dennison RJ, Aderman CM, Chen J, Guerin KI, Sapieha P, Stahl A, Willett KL, Smith LE. Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis. Nat Protoc. 2009;4(11):1565-1573.

     Not in our library10.1038/nprot.2009.187

457. 457.

     Xiao S, Bucher F, Wu Y, Rokem A, Lee CS, Marra KV, Fallon R, Diaz-Aguilar S, Aguilar E, Friedlander M, Lee AY. Fully automated, deep learning segmentation of oxygen-induced retinopathy images. JCI Insight. 2017.

     Not in our library10.1172/jci.insight.97585

458. 458.

     Stahl A, Chen J, Sapieha P, Seaward MR, Krah NM, Dennison RJ, Favazza T, Bucher F, Lofqvist C, Ong H, Hellstrom A, Chemtob S, Akula JD, Smith LE. Postnatal weight gain modifies severity and functional outcome of oxygen-induced proliferative retinopathy. Am J Pathol. 2010;177(6):2715-2723.

     Not in our library10.2353/ajpath.2010.100526

459. 459.

     de Jong PT. Age-related macular degeneration. N Engl J Med. 2006;355(14):1474-1485.

     Not in our library10.1056/nejmra062326

460. 460.

     Friedman DS, O’Colmain BJ, Munoz B, Tomany SC, McCarty C, de Jong PT, Nemesure B, Mitchell P, Kempen J. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol. 2004;122(4):564-572.

     Not in our library10.1001/archopht.122.4.564

461. 461.

     Jost M, Maillard C, Lecomte J, Lambert V, Tjwa M, Blaise P, Alvarez Gonzalez ML, Bajou K, Blacher S, Motte P, Humblet C, Defresne MP, Thiry M, Frankenne F, Gothot A, Carmeliet P, Rakic JM, Foidart JM, Noel A. Tumoral and choroidal vascularization: differential cellular mechanisms involving plasminogen activator inhibitor type I. Am J Pathol. 2007;171(4):1369-1380.

     Not in our library10.2353/ajpath.2007.070074

462. 462.

     Pennesi ME, Neuringer M, Courtney RJ. Animal models of age related macular degeneration. Mol Aspects Med. 2012;33(4):487-509.

     Not in our library10.1016/j.mam.2012.06.003

463. 463.

     Poor SH, Qiu Y, Fassbender ES, Shen S, Woolfenden A, Delpero A, Kim Y, Buchanan N, Gebuhr TC, Hanks SM, Meredith EL, Jaffee BD, Dryja TP. Reliability of the mouse model of choroidal neovascularization induced by laser photocoagulation. Invest Ophthalmol Vis Sci. 2014;55(10):6525-6534.

     Not in our library10.1167/iovs.14-15067

464. 464.

     Ryan SJ. The development of an experimental model of subretinal neovascularization in disciform macular degeneration. Trans Am Ophthalmol Soc. 1979;77:707-745.

     Not in our library

465. 465.

     Krzystolik MG, Afshari MA, Adamis AP, Gaudreault J, Gragoudas ES, Michaud NA, Li W, Connolly E, O’Neill CA, Miller JW. Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment. Arch Ophthalmol. 2002;120(3):338-346.

     Not in our library10.1001/archopht.120.3.338

466. 466.

     Lambert V, Lecomte J, Hansen S, Blacher S, Gonzalez ML, Struman I, Sounni NE, Rozet E, de Tullio P, Foidart JM, Rakic JM, Noel A. Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice. Nat Protoc. 2013;8(11):2197-2211.

     Not in our library10.1038/nprot.2013.135

467. 467.

     Gong Y, Li J, Sun Y, Fu Z, Liu CH, Evans L, Tian K, Saba N, Fredrick T, Morss P, Chen J, Smith LE. Optimization of an Image-Guided Laser-Induced Choroidal Neovascularization Model in Mice. PLoS ONE. 2015;10(7):e0132643.

     Not in our library10.1371/journal.pone.0132643

468. 468.

     Zhu Y, Lu Q, Shen J, Zhang L, Gao Y, Shen X, Xie B. Improvement and optimization of standards for a preclinical animal test model of laser induced choroidal neovascularization. PLoS ONE. 2014;9(4):e94743.

     Not in our library10.1371/journal.pone.0094743

469. 469.

     Sandison J. The transparent chamber of the rabbit’s ear giving a complete description of improved techniques of construction and introduction and general account of growth and behaviour of living cells and tissues seen with the microscope. Am J Anat. 1928;41:447-472.

     Not in our library

470. 470.

     Jain RK, Munn LL, Fukumura D. Rabbit ear chambers. Cold Spring Harb Protoc. 2012;7:813-814.

     Not in our library10.1101/pdb.prot070045

471. 471.

     Algire GH. An adaptation of the transparent chamber technique to the mouse. J Natl Cancer Inst. 1943;4:1-11.

     Not in our library

472. 472.

     Jain RK, Schlenger K, Hockel M, Yuan F. Quantitative angiogenesis assays: progress and problems. Nat Med. 1997;3(11):1203-1208.

     Not in our library10.1038/nm1197-1203

473. 473.

     Fukumura D, Duda DG, Munn LL, Jain RK. Tumor micro-vasculature and microenvironment: novel insights through intra-vital imaging in pre-clinical models. Microcirculation. 2010;17(3):206-225.

     Not in our library10.1111/j.1549-8719.2010.00029.x

474. 474.

     Jain RK. Angiogenesis and lymphangiogenesis in tumors: insights from intravital microscopy. Cold Spring Harb Symp Quant Biol. 2002;67:239-248.

     Not in our library10.1101/sqb.2002.67.239

475. 475.

     Leunig M, Yuan F, Menger MD, Boucher Y, Goetz AE, Messmer K, Jain RK. Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice. Can Res. 1992;52(23):6553-6560.

     Not in our library

476. 476.

     Yuan F, Salehi HA, Boucher Y, Vasthare US, Tuma RF, Jain RK. Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Can Res. 1994;54(17):4564-4568.

     Not in our library

477. 477.

     Dellian M, Witwer BP, Salehi HA, Yuan F, Jain RK. Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment. Am J Pathol. 1996;149(1):59-71.

     Not in our library

478. 478.

     Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, Anolik R, Huang Y, Martin JD, Kamoun W, Knevels E, Schmidt T, Farrar CT, Vakoc BJ, Mohan N, Chung E, Roberge S, Peterson T, Bais C, Zhelyazkova BH, Yip S, Hasselblatt M, Rossig C, Niemeyer E, Ferrara N, Klagsbrun M, Duda DG, Fukumura D, Xu L, Carmeliet P, Jain RK. Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell. 2013;152(5):1065-1076.

     Not in our library10.1016/j.cell.2013.01.036

479. 479.

     Askoxylakis V, Badeaux M, Roberge S, Batista A, Kirkpatrick N, Snuderl M, Amoozgar Z, Seano G, Ferraro GB, Chatterjee S, Xu L, Fukumura D, Duda DG, Jain RK. A cerebellar window for intravital imaging of medulloblastoma in mice. Nat Protoc. 2017;12(11):2251-2262.

     Not in our library10.1038/nprot.2017.101

480. 480.

     Reiberger T, Chen Y, Ramjiawan RR, Hato T, Fan C, Samuel R, Roberge S, Huang P, Lauwers GY, Zhu AX, Bardeesy N, Jain RK, Duda DG. An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis. Nat Protoc. 2015;10(8):1264-1274.

     Not in our library10.1038/nprot.2015.080

481. 481.

     Rahbari NN, Kedrin D, Incio J, Liu H, Ho WW, Nia HT, Edrich CM, Jung K, Daubriac J, Chen I, Heishi T, Martin JD, Huang Y, Maimon N, Reissfelder C, Weitz J, Boucher Y, Clark JW, Grodzinsky AJ, Duda DG, Jain RK, Fukumura D. Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases. Sci Transl Med. 2016;8(360):360ra135.

     Not in our library10.1126/scitranslmed.aaf5219

482. 482.

     Jain RK, Munn LL, Fukumura D. Lung window preparation in mice. Cold Spring Harb Protoc. 2013.

     Not in our library10.1101/pdb.prot072678

483. 483.

     Tsuzuki Y, Mouta Carreira C, Bockhorn M, Xu L, Jain RK, Fukumura D. Pancreas microenvironment promotes VEGF expression and tumor growth: novel window models for pancreatic tumor angiogenesis and microcirculation. Lab Investig J Tech Methods Pathol. 2001;81(10):1439-1451.

     Not in our library10.1038/labinvest.3780357

484. 484.

     Jain RK, Munn LL, Fukumura D. Pancreatic tumor preparation in mice. Cold Spring Harb Protoc. 2012.

     Not in our library10.1101/pdb.prot072363

485. 485.

     Vakoc BJ, Lanning RM, Tyrrell JA, Padera TP, Bartlett LA, Stylianopoulos T, Munn LL, Tearney GJ, Fukumura D, Jain RK, Bouma BE. Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging. Nat Med. 2009;15(10):1219-1223.

     Not in our library10.1038/nm.1971

486. 486.

     Jeong HS, Jones D, Liao S, Wattson DA, Cui CH, Duda DG, Willett CG, Jain RK, Padera TP. Investigation of the lack of angiogenesis in the formation of lymph node metastases. J Natl Cancer Inst. 2015.

     Not in our library10.1093/jnci/djv155

487. 487.

     Brown EB, Campbell RB, Tsuzuki Y, Xu L, Carmeliet P, Fukumura D, Jain RK. In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy. Nat Med. 2001;7(7):864-868.

     Not in our library10.1038/89997

488. 488.

     Bruns, et al. Science Trans Med. 2017.

     Not in our library

489. 489.

     Chen O, Zhao J, Chauhan VP, Cui J, Wong C, Harris DK, Wei H, Han HS, Fukumura D, Jain RK, Bawendi MG. Compact high-quality CdSe-CdS core-shell nanocrystals with narrow emission linewidths and suppressed blinking. Nat Mater. 2013;12(5):445-451.

     Not in our library10.1038/nmat3539

490. 490.

     Stroh M, Zimmer JP, Duda DG, Levchenko TS, Cohen KS, Brown EB, Scadden DT, Torchilin VP, Bawendi MG, Fukumura D, Jain RK. Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo. Nat Med. 2005;11(6):678-682.

     Not in our library10.1038/nm1247

491. 491.

     Brown E, McKee T, diTomaso E, Pluen A, Seed B, Boucher Y, Jain RK. Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation. Nat Med. 2003;9(6):796-800.

     Not in our library10.1038/nm879

492. 492.

     Perentes JY, McKee TD, Ley CD, Mathiew H, Dawson M, Padera TP, Munn LL, Jain RK, Boucher Y. In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts. Nat Methods. 2009;6(2):143-145.

     Not in our library10.1038/nmeth.1295

493. 493.

     Gruionu G, Bazou D, Maimon N, Onita-Lenco M, Gruionu LG, Huang P, Munn LL. Implantable tissue isolation chambers for analyzing tumor dynamics in vivo. Lab Chip. 2016;16(10):1840-1851.

     Not in our library10.1039/c6lc00237d

494. 494.

     Jain RK, Munn LL, Fukumura D. Measuring angiogenesis and hemodynamics in mice. Cold Spring Harb Protoc. 2013;4:354-358.

     Not in our library10.1101/pdb.prot073916

495. 495.

     Kamoun WS, Chae SS, Lacorre DA, Tyrrell JA, Mitre M, Gillissen MA, Fukumura D, Jain RK, Munn LL. Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks. Nat Methods. 2010;7(8):655-660.

     Not in our library10.1038/nmeth.1475

496. 496.

     Kirkpatrick ND, Chung E, Cook DC, Han X, Gruionu G, Liao S, Munn LL, Padera TP, Fukumura D, Jain RK. Video-rate resonant scanning multiphoton microscopy: an emerging technique for intravital imaging of the tumor microenvironment. Intravital. 2012.

     Not in our library10.4161/intv.21557

497. 497.

     Melder RJ, Koenig GC, Witwer BP, Safabakhsh N, Munn LL, Jain RK. During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium. Nat Med. 1996;2(9):992-997.

     Not in our library10.1038/nm0996-992

498. 498.

     Alexandrakis G, Brown EB, Tong RT, McKee TD, Campbell RB, Boucher Y, Jain RK. Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors. Nat Med. 2004;10(2):203-207.

     Not in our library10.1038/nm981

499. 499.

     Chauhan VP, Stylianopoulos T, Martin JD, Popovic Z, Chen O, Kamoun WS, Bawendi MG, Fukumura D, Jain RK. Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner. Nat Nanotechnol. 2012;7(6):383-388.

     Not in our library10.1038/nnano.2012.45

500. 500.

     Chauhan VP, Martin JD, Liu H, Lacorre DA, Jain SR, Kozin SV, Stylianopoulos T, Mousa AS, Han X, Adstamongkonkul P, Popovic Z, Huang P, Bawendi MG, Boucher Y, Jain RK. Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels. Nat Commun. 2013;4:2516.

     Not in our library10.1038/ncomms3516

501. 501.

     Hobbs SK, Monsky WL, Yuan F, Roberts WG, Griffith L, Torchilin VP, Jain RK. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci USA. 1998;95(8):4607-4612.

     Not in our library10.1073/pnas.95.8.4607

502. 502.
     Direct in vivo measurement of targeted binding in a human tumor xenograft · 1997

     Not checked
503. 503.

     Martin GR, Jain RK. Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy. Can Res. 1994;54(21):5670-5674.

     Not in our library

504. 504.

     Torres Filho IP, Leunig M, Yuan F, Intaglietta M, Jain RK. Noninvasive measurement of microvascular and interstitial oxygen profiles in a human tumor in SCID mice. Proc Natl Acad Sci USA. 1994;91(6):2081-2085.

     Not in our library10.1073/pnas.91.6.2081

505. 505.

     Helmlinger G, Yuan F, Dellian M, Jain RK. Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat Med. 1997;3(2):177-182.

     Not in our library10.1038/nm0297-177

506. 506.

     Fukumura D, Chen Y, Gohongi T, Seed B, Jain RK. VEGF expression in tumors is regulated by oxygen gradient rather than absolute level of hypoxia itself. Proc Am Assoc Cancer Res. 1998;39:271.

     Not in our library

507. 507.

     Yuan F, Chen Y, Dellian M, Safabakhsh N, Ferrara N, Jain RK. Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc Natl Acad Sci USA. 1996;93(25):14765-14770.

     Not in our library10.1073/pnas.93.25.14765

508. 508.

     Padera TP, Stoll BR, So PT, Jain RK. Conventional and high-speed intravital multiphoton laser scanning microscopy of microvasculature, lymphatics, and leukocyte-endothelial interactions. Mol Imaging. 2002;1(1):9-15.

     Not in our library10.1162/15353500200200004

509. 509.

     Cheng G, Liao S, Kit Wong H, Lacorre DA, di Tomaso E, Au P, Fukumura D, Jain RK, Munn LL. Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis. Blood. 2011;118(17):4740-4749.

     Not in our library10.1182/blood-2011-02-338426

510. 510.

     Winkler F, Kozin SV, Tong RT, Chae SS, Booth MF, Garkavtsev I, Xu L, Hicklin DJ, Fukumura D, di Tomaso E, Munn LL, Jain RK. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell. 2004;6(6):553-563.

     Not in our library10.1016/j.ccr.2004.10.011

511. 511.

     Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D. Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. J Clin Invest. 2017.

     Not in our library10.1172/jci93182

512. 512.

     Goel S, Gupta N, Walcott BP, Snuderl M, Kesler CT, Kirkpatrick ND, Heishi T, Huang Y, Martin JD, Ager E, Samuel R, Wang S, Yazbek J, Vakoc BJ, Peterson RT, Padera TP, Duda DG, Fukumura D, Jain RK. Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression. J Natl Cancer Inst. 2013;105(16):1188-1201.

     Not in our library10.1093/jnci/djt164

513. 513.

     Kodack DP, Askoxylakis V, Ferraro GB, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao ZA, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, Wong CSF, Kloepper J, Das R, Tam A, Tanboon J, Duda DG, Miller CR, Siegel MB, Anders CK, Sanders M, Estrada MV, Schlegel R, Arteaga CL, Brachtel E, Huang A, Fukumura D, Engelman JA, Jain RK. The brain microenvironment mediates resistance in luminal breast cancer to PI3 K inhibition through HER3 activation. Sci Transl Med. 2017.

     Not in our library10.1126/scitranslmed.aal4682

514. 514.

     Lagerweij T, Dusoswa SA, Negrean A, Hendrikx EML, de Vries HE, Kole J, Garcia-Vallejo JJ, Mansvelder HD, Vandertop WP, Noske DP, Tannous BA, Musters RJP, van Kooyk Y, Wesseling P, Zhao XW, Wurdinger T. Optical clearing and fluorescence deep-tissue imaging for 3D quantitative analysis of the brain tumor microenvironment. Angiogenesis. 2017;20(4):533-546.

     Not in our library10.1007/s10456-017-9565-6

515. 515.

     Farrar CT, Kamoun WS, Ley CD, Kim YR, Kwon SJ, Dai G, Rosen BR, di Tomaso E, Jain RK, Sorensen AG. In vivo validation of MRI vessel caliber index measurement methods with intravital optical microscopy in a U87 mouse brain tumor model. Neuro Oncol. 2010;12(4):341-350.

     Not in our library10.1093/neuonc/nop032

516. 516.

     Gazit Y, Baish JW, Safabakhsh N, Leunig M, Baxter LT, Jain RK. Fractal characteristics of tumor vascular architecture during tumor growth and regression. Microcirculation. 1997;4(4):395-402.

     Not in our library10.3109/10739689709146803

517. 517.

     Gazit Y, Berk DA, Leunig M, Baxter LT, Jain RK. Scale-invariant behavior and vascular network formation in normal and tumor tissue. Phys Rev Lett. 1995;75(12):2428-2431.

     Not in our library10.1103/physrevlett.75.2428

518. 518.

     Baish JW, Stylianopoulos T, Lanning RM, Kamoun WS, Fukumura D, Munn LL, Jain RK. Scaling rules for diffusive drug delivery in tumor and normal tissues. Proc Natl Acad Sci USA. 2011;108(5):1799-1803.

     Not in our library10.1073/pnas.1018154108

519. 519.

     Baish JW, Jain RK. Cancer, angiogenesis and fractals. Nat Med. 1998;4(9):984.

     Not in our library10.1038/1952

520. 520.

     Hanahan D. Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature. 1985;315(6015):115-122.

     Not in our library10.1038/315115a0

521. 521.

     Folkman J, Merler E, Abernathy C, Williams G. Isolation of a tumor factor responsible for angiogenesis. J Exp Med. 1971;133(2):275-288.

     Not in our library10.1084/jem.133.2.275

522. 522.

     Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature. 1989;339(6219):58-61.

     Not in our library10.1038/339058a0

523. 523.

     Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 1996;86(3):353-364.

     Not in our library10.1016/s0092-8674(00)80108-7

524. 524.

     Christofori G, Naik P, Hanahan D. Vascular endothelial growth factor and its receptors, flt-1 and flk-1, are expressed in normal pancreatic islets and throughout islet cell tumorigenesis. Mol Endocrinol. 1995;9(12):1760-1770.

     Not in our library10.1210/mend.9.12.8614412

525. 525.

     Inoue M, Hager JH, Ferrara N, Gerber HP, Hanahan D. VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis. Cancer Cell. 2002;1(2):193-202.

     Not in our library10.1016/s1535-6108(02)00031-4

526. 526.

     Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z, Hanahan D. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol. 2000;2(10):737-744.

     Not in our library10.1038/35036374

527. 527.

     Parangi S, O’Reilly M, Christofori G, Holmgren L, Grosfeld J, Folkman J, Hanahan D. Antiangiogenic therapy of transgenic mice impairs de novo tumor growth. Proc Natl Acad Sci USA. 1996;93(5):2002-2007.

     Not in our library10.1073/pnas.93.5.2002

528. 528.

     Bergers G, Javaherian K, Lo KM, Folkman J, Hanahan D. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science. 1999;284(5415):808-812.

     Not in our library10.1126/science.284.5415.808

529. 529.

     Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest. 2003;111(9):1287-1295.

     Not in our library10.1172/jci17929

530. 530.

     Paez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Vinals F, Inoue M, Bergers G, Hanahan D, Casanovas O. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell. 2009;15(3):220-231.

     Not in our library10.1016/j.ccr.2009.01.027

531. 531.

     Raymond E, Dahan L, Raoul JL, Bang YJ, Borbath I, Lombard-Bohas C, Valle J, Metrakos P, Smith D, Vinik A, Chen JS, Horsch D, Hammel P, Wiedenmann B, Van Cutsem E, Patyna S, Lu DR, Blanckmeister C, Chao R, Ruszniewski P. Sunitinib malate for the treatment of pancreatic neuroendocrine tumors. N Engl J Med. 2011;364(6):501-513.

     Not in our library10.1056/nejmoa1003825

532. 532.

     Chiu CW, Nozawa H, Hanahan D. Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target of rapamycin and epidermal growth factor receptor in a preclinical model of pancreatic neuroendocrine carcinogenesis. J Clin Oncol. 2010;28(29):4425-4433.

     Not in our library10.1200/jco.2010.28.0198

533. 533.

     Yao JC, Pavel M, Lombard-Bohas C, Van Cutsem E, Voi M, Brandt U, He W, Chen D, Capdevila J, de Vries EGE, Tomassetti P, Hobday T, Pommier R, Oberg K. Everolimus for the treatment of advanced pancreatic neuroendocrine tumors: overall survival and circulating biomarkers from the randomized, phase III RADIANT-3 study. J Clin Oncol. 2016;34(32):3906-3913.

     Not in our library10.1200/jco.2016.68.0702

534. 534.

     Scarpa A, Chang DK, Nones K, Corbo V, Patch AM, Bailey P, Lawlor RT, Johns AL, Miller DK, Mafficini A, Rusev B, Scardoni M, Antonello D, Barbi S, Sikora KO, Cingarlini S, Vicentini C, McKay S, Quinn MC, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, McLean S, Nourse C, Nourbakhsh E, Wilson PJ, Anderson MJ, Fink JL, Newell F, Waddell N, Holmes O, Kazakoff SH, Leonard C, Wood S, Xu Q, Nagaraj SH, Amato E, Dalai I, Bersani S, Cataldo I, Dei Tos AP, Capelli P, Davi MV, Landoni L, Malpaga A, Miotto M, Whitehall VL, Leggett BA, Harris JL, Harris J, Jones MD, Humphris J, Chantrill LA, Chin V, Nagrial AM, Pajic M, Scarlett CJ, Pinho A, Rooman I, Toon C, Wu J, Pinese M, Cowley M, Barbour A, Mawson A, Humphrey ES, Colvin EK, Chou A, Lovell JA, Jamieson NB, Duthie F, Gingras MC, Fisher WE, Dagg RA, Lau LM, Lee M, Pickett HA, Reddel RR, Samra JS, Kench JG, Merrett ND, Epari K, Nguyen NQ, Zeps N, Falconi M, Simbolo M, Butturini G, Van Buren G, Partelli S, Fassan M, Genome APC, Khanna KK, Gill AJ, Wheeler DA, Gibbs RA, Musgrove EA, Bassi C, Tortora G, Pederzoli P, Pearson JV, Waddell N, Biankin AV, Grimmond SM. Whole-genome landscape of pancreatic neuroendocrine tumours. Nature. 2017;543(7643):65-71.

     Not in our library10.1038/nature21063

535. 535.

     Sadanandam A, Wullschleger S, Lyssiotis CA, Grotzinger C, Barbi S, Bersani S, Korner J, Wafy I, Mafficini A, Lawlor RT, Simbolo M, Asara JM, Blaker H, Cantley LC, Wiedenmann B, Scarpa A, Hanahan D. A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics. Cancer Discov. 2015;5(12):1296-1313.

     Not in our library10.1158/2159-8290.cd-15-0068

536. 536.

     Mancuso MR, Davis R, Norberg SM, O’Brien S, Sennino B, Nakahara T, Yao VJ, Inai T, Brooks P, Freimark B, Shalinsky DR, Hu-Lowe DD, McDonald DM. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest. 2006;116(10):2610-2621.

     Not in our library10.1172/jci24612

537. 537.

     Casanovas O, Hicklin DJ, Bergers G, Hanahan D. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell. 2005;8(4):299-309.

     Not in our library10.1016/j.ccr.2005.09.005

538. 538.

     Rivera LB, Meyronet D, Hervieu V, Frederick MJ, Bergsland E, Bergers G. Intratumoral myeloid cells regulate responsiveness and resistance to antiangiogenic therapy. Cell Rep. 2015;11(4):577-591.

     Not in our library10.1016/j.celrep.2015.03.055

539. 539.

     Rivera LB, Bergers G. Intertwined regulation of angiogenesis and immunity by myeloid cells. Trends Immunol. 2015;36(4):240-249.

     Not in our library10.1016/j.it.2015.02.005

540. 540.

     Allen E, Jabouille A, Rivera LB, Lodewijckx I, Missiaen R, Steri V, Feyen K, Tawney J, Hanahan D, Michael IP, Bergers G. Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation. Sci Transl Med. 2017.

     Not in our library10.1126/scitranslmed.aak9679

541. 541.

     Ellis LM, Reardon DA. Cancer: the nuances of therapy. Nature. 2009;458(7236):290-292.

     Not in our library10.1038/458290a

542. 542.

     Guy CT, Cardiff RD, Muller WJ. Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol. 1992;12(3):954-961.

     Not in our library10.1128/mcb.12.3.954-961.1992

543. 543.

     Lin EY, Nguyen AV, Russell RG, Pollard JW. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med. 2001;193(6):727-740.

     Not in our library10.1084/jem.193.6.727

544. 544.

     Lin EY, Jones JG, Li P, Zhu L, Whitney KD, Muller WJ, Pollard JW. Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am J Pathol. 2003;163(5):2113-2126.

     Not in our library10.1016/s0002-9440(10)63568-7

545. 545.

     Lin EY, Li JF, Gnatovskiy L, Deng Y, Zhu L, Grzesik DA, Qian H, Xue XN, Pollard JW. Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Can Res. 2006;66(23):11238-11246.

     Not in our library10.1158/0008-5472.can-06-1278

546. 546.

     DeNardo DG, Brennan DJ, Rexhepaj E, Ruffell B, Shiao SL, Madden SF, Gallagher WM, Wadhwani N, Keil SD, Junaid SA, Rugo HS, Hwang ES, Jirstrom K, West BL, Coussens LM. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov. 2011;1(1):54-67.

     Not in our library10.1158/2159-8274.cd-10-0028

547. 547.

     Keklikoglou I, Kadioglu E, Bissinger S, Langlois B, Bellotti A, Orend G, Ries CH, De Palma M. Periostin limits tumor response to VEGFA inhibition. Cell reports. 2018;22(10):2530-2540.

     Not in our library10.1016/j.celrep.2018.02.035

548. 548.

     Lin EY, Li JF, Bricard G, Wang W, Deng Y, Sellers R, Porcelli SA, Pollard JW. Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages. Mol Oncol. 2007;1(3):288-302.

     Not in our library10.1016/j.molonc.2007.10.003

549. 549.

     Stockmann C, Doedens A, Weidemann A, Zhang N, Takeda N, Greenberg JI, Cheresh DA, Johnson RS. Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis. Nature. 2008;456(7223):814-818.

     Not in our library10.1038/nature07445

550. 550.

     De Palma M, Mazzieri R, Politi LS, Pucci F, Zonari E, Sitia G, Mazzoleni S, Moi D, Venneri MA, Indraccolo S, Falini A, Guidotti LG, Galli R, Naldini L. Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis. Cancer Cell. 2008;14(4):299-311.

     Not in our library10.1016/j.ccr.2008.09.004

551. 551.

     Mazzieri R, Pucci F, Moi D, Zonari E, Ranghetti A, Berti A, Politi LS, Gentner B, Brown JL, Naldini L, De Palma M. Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer Cell. 2011;19(4):512-526.

     Not in our library10.1016/j.ccr.2011.02.005

552. 552.

     Jain RK. Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia. Cancer Cell. 2014;26(5):605-622.

     Not in our library10.1016/j.ccell.2014.10.006

553. 553.

     Yeo EJ, Cassetta L, Qian BZ, Lewkowich I, Li JF, Stefater JA, Smith AN, Wiechmann LS, Wang Y, Pollard JW, Lang RA. Myeloid WNT7b mediates the angiogenic switch and metastasis in breast cancer. Can Res. 2014;74(11):2962-2973.

     Not in our library10.1158/0008-5472.can-13-2421

554. 554.

     Harney AS, Arwert EN, Entenberg D, Wang Y, Guo P, Qian BZ, Oktay MH, Pollard JW, Jones JG, Condeelis JS. Real-time imaging reveals local, transient vascular permeability, and tumor cell intravasation stimulated by TIE2hi macrophage-derived VEGFA. Cancer Discov. 2015;5(9):932-943.

     Not in our library10.1158/2159-8290.cd-15-0012

555. 555.

     Wyckoff JB, Wang Y, Lin EY, Li JF, Goswami S, Stanley ER, Segall JE, Pollard JW, Condeelis J. Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Can Res. 2007;67(6):2649-2656.

     Not in our library10.1158/0008-5472.can-06-1823

556. 556.
     Macrophages orchestrate breast cancer early dissemination and metastasis · 2018

     No notice
557. 557.

     Rigamonti N, Kadioglu E, Keklikoglou I, Wyser Rmili C, Leow CC, De Palma M. Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade. Cell Rep. 2014;8(3):696-706.

     Not in our library10.1016/j.celrep.2014.06.059

558. 558.

     Schmittnaegel M, Rigamonti N, Kadioglu E, Cassara A, Wyser Rmili C, Kiialainen A, Kienast Y, Mueller HJ, Ooi CH, Laoui D, De Palma M. Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade. Sci Transl Med. 2017.

     Not in our library10.1126/scitranslmed.aak9670

559. 559.

     Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer. 2008;8(8):592-603.

     Not in our library10.1038/nrc2442

560. 560.

     Schmittnaegel M, De Palma M. Reprogramming tumor blood vessels for enhancing immunotherapy. Trends Cancer. 2017;3(12):809-812.

     Not in our library10.1016/j.trecan.2017.10.002

561. 561.

     Fukumura D, Kloepper J, Amoozgar Z, Duda DG, Jain RK. Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges. Nat Rev Clin Oncol. 2018.

     Not in our library10.1038/nrclinonc.2018.29

562. 562.

     Donnem T, Reynolds AR, Kuczynski EA, Gatter K, Vermeulen PB, Kerbel RS, Harris AL, Pezzella F. Non-angiogenic tumours and their influence on cancer biology. Nat Rev Cancer. 2018.

     Not in our library10.1038/nrc.2018.14

563. 563.

     Eklund L, Bry M, Alitalo K. Mouse models for studying angiogenesis and lymphangiogenesis in cancer. Mol Oncol. 2013;7(2):259-282.

     Not in our library10.1016/j.molonc.2013.02.007

564. 564.

     Blouw B, Song H, Tihan T, Bosze J, Ferrara N, Gerber HP, Johnson RS, Bergers G. The hypoxic response of tumors is dependent on their microenvironment. Cancer Cell. 2003;4(2):133-146.

     Not in our library10.1016/s1535-6108(03)00194-6

565. 565.

     Pezzella F, Di Bacco A, Andreola S, Nicholson AG, Pastorino U, Harris AL. Angiogenesis in primary lung cancer and lung secondaries. Eur J Cancer Part A. 1996;32(14):2494-2500.

     Not in our library10.1016/s0959-8049(96)00377-2

566. 566.

     Kuczynski EA, Yin M, Bar-Zion A, Lee CR, Butz H, Man S, Daley F, Vermeulen PB, Yousef GM, Foster FS, Reynolds AR, Kerbel RS. Co-option of liver vessels and not sprouting angiogenesis drives acquired sorafenib resistance in hepatocellular carcinoma. J Natl Cancer Inst. 2016;108(8):djw030.

     Not in our library10.1093/jnci/djw030

567. 567.

     Jeong HS, Jones D, Liao S, Wattson DA, Cui CH, Duda DG, Willett CG, Jain RK, Padera TP. Investigation of the lack of angiogenesis in the formation of lymph node metastases. J Natl Cancer Inst. 2015.

     Not in our library10.1093/jnci/djv155

568. 568.

     Warth A. Spread through air spaces (STAS): a comprehensive update. Transl Lung Cancer Res. 2017;6(5):501-507.

     Not in our library10.21037/tlcr.2017.06.08

569. 569.

     Kuczynski EA, Vermeulen PB, Pezzella F, Kerbel RS, Reynolds AR. Vessel co-option in cancer: mechanisms and clinical implications.

     Not in our library10.1038/s41571-019-0181-9

570. 570.

     Seaman S, Zhu Z, Saha S, Zhang XM, Yang MY, Hilton MB, Morris K, Szot C, Morris H, Swing DA, Tessarollo L, Smith SW, Degrado S, Borkin D, Jain N, Scheiermann J, Feng Y, Wang Y, Li J, Welsch D, DeCrescenzo G, Chaudhary A, Zudaire E, Klarmann KD, Keller JR, Dimitrov DS, St Croix B. Eradication of tumors through simultaneous ablation of CD276/B7–H3-positive tumor cells and tumor vasculature. Cancer Cell. 2017;31(4):501-515.

     Not in our library10.1016/j.ccell.2017.03.005

571. 571.

     Belch JJ, Topol EJ, Agnelli G, Bertrand M, Califf RM, Clement DL, Creager MA, Easton JD, Gavin JR, Greenland P, Hankey G, Hanrath P, Hirsch AT, Meyer J, Smith SC, Sullivan F, Weber MA. Critical issues in peripheral arterial disease detection and management: a call to action. Arch Intern Med. 2003;163(8):884-892.

     Not in our library10.1001/archinte.163.8.884

572. 572.

     Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG, Group TIW. Inter-society consensus for the management of peripheral arterial disease (TASC II). J Vasc Surg. 2007;45(Suppl S):S5-S67.

     Not in our library10.1016/j.jvs.2006.12.037

573. 573.

     Annex BH. Therapeutic angiogenesis for critical limb ischaemia. Nat Rev Cardiol. 2013;10(7):387-396.

     Not in our library10.1038/nrcardio.2013.70

574. 574.

     Cooke JP, Losordo DW. Modulating the vascular response to limb ischemia: angiogenic and cell therapies. Circ Res. 2015;116(9):1561-1578.

     Not in our library10.1161/circresaha.115.303565

575. 575.

     van Oostrom MC, van Oostrom O, Quax PH, Verhaar MC, Hoefer IE. Insights into mechanisms behind arteriogenesis: what does the future hold? J Leukoc Biol. 2008;84(6):1379-1391.

     Not in our library10.1189/jlb.0508281

576. 576.

     Couffinhal T, Silver M, Zheng LP, Kearney M, Witzenbichler B, Isner JM. Mouse model of angiogenesis. Am J Pathol. 1998;152(6):1667-1679.

     Not in our library

577. 577.

     Adini A, Adini I, Chi ZL, Derda R, Birsner AE, Matthews BD, D’Amato RJ. A novel strategy to enhance angiogenesis in vivo using the small VEGF-binding peptide PR1P. Angiogenesis. 2017;20(3):399-408.

     Not in our library10.1007/s10456-017-9556-7

578. 578.

     Sarkar C, Ganju RK, Pompili VJ, Chakroborty D. Enhanced peripheral dopamine impairs post-ischemic healing by suppressing angiotensin receptor type 1 expression in endothelial cells and inhibiting angiogenesis. Angiogenesis. 2017;20(1):97-107.

     Not in our library10.1007/s10456-016-9531-8

579. 579.

     Stabile E, Burnett MS, Watkins C, Kinnaird T, Bachis A, la Sala A, Miller JM, Shou M, Epstein SE, Fuchs S. Impaired arteriogenic response to acute hindlimb ischemia in CD4-knockout mice. Circulation. 2003;108(2):205-210.

     Not in our library10.1161/01.cir.0000079225.50817.71

580. 580.

     Tang G, Charo DN, Wang R, Charo IF, Messina L. CCR2−/− knockout mice revascularize normally in response to severe hindlimb ischemia. J Vasc Surg. 2004;40(4):786-795.

     Not in our library10.1016/j.jvs.2004.07.012

581. 581.

     van Weel V, Toes RE, Seghers L, Deckers MM, de Vries MR, Eilers PH, Sipkens J, Schepers A, Eefting D, van Hinsbergh VW, van Bockel JH, Quax PH. Natural killer cells and CD4+ T-cells modulate collateral artery development. Arterioscler Thromb Vasc Biol. 2007;27(11):2310-2318.

     Not in our library10.1161/atvbaha.107.151407

582. 582.

     Masaki I, Yonemitsu Y, Yamashita A, Sata S, Tanii M, Komori K, Nakagawa K, Hou X, Nagai Y, Hasegawa M, Sugimachi K, Sueishi K. Angiogenic gene therapy for experimental critical limb ischemia: acceleration of limb loss by overexpression of vascular endothelial growth factor 165 but not of fibroblast growth factor-2. Circ Res. 2002;90(9):966-973.

     Not in our library10.1161/01.res.0000019540.41697.60

583. 583.

     Westvik TS, Fitzgerald TN, Muto A, Maloney SP, Pimiento JM, Fancher TT, Magri D, Westvik HH, Nishibe T, Velazquez OC, Dardik A. Limb ischemia after iliac ligation in aged mice stimulates angiogenesis without arteriogenesis. J Vasc Surg. 2009;49(2):464-473.

     Not in our library10.1016/j.jvs.2008.08.077

584. 584.

     Chen M, Fan H, Ledford BT, Farah Z, Barron C, Liu Z, He JQ. Impacts of femoral artery and vein excision versus femoral artery excision on the hindlimb ischemic model in CD-1 mice. Microvasc Res. 2017;110:48-55.

     Not in our library10.1016/j.mvr.2016.12.006

585. 585.

     Hellingman AA, Bastiaansen AJ, de Vries MR, Seghers L, Lijkwan MA, Lowik CW, Hamming JF, Quax PH. Variations in surgical procedures for hind limb ischaemia mouse models result in differences in collateral formation. Eur J Vasc Endovasc Surg. 2010;40(6):796-803.

     Not in our library10.1016/j.ejvs.2010.07.009

586. 586.

     Krishna SM, Omer SM, Golledge J. Evaluation of the clinical relevance and limitations of current pre-clinical models of peripheral artery disease. Clin Sci. 2016;130(3):127-150.

     Not in our library10.1042/cs20150435

587. 587.

     Lotfi S, Patel AS, Mattock K, Egginton S, Smith A, Modarai B. Towards a more relevant hind limb model of muscle ischaemia. Atherosclerosis. 2013;227(1):1-8.

     Not in our library10.1016/j.atherosclerosis.2012.10.060

588. 588.

     van Weel V, Deckers MM, Grimbergen JM, van Leuven KJ, Lardenoye JH, Schlingemann RO, van Nieuw Amerongen GP, van Bockel JH, van Hinsbergh VW, Quax PH. Vascular endothelial growth factor overexpression in ischemic skeletal muscle enhances myoglobin expression in vivo. Circ Res. 2004;95(1):58-66.

     Not in our library10.1161/01.res.0000133247.69803.c3

589. 589.

     Lijkwan MA, Hellingman AA, Bos EJ, van der Bogt KE, Huang M, Kooreman NG, de Vries MR, Peters HA, Robbins RC, Hamming JF, Quax PH, Wu JC. Short hairpin RNA gene silencing of prolyl hydroxylase-2 with a minicircle vector improves neovascularization of hindlimb ischemia. Hum Gene Ther. 2014;25(1):41-49.

     Not in our library10.1089/hum.2013.110

590. 590.

     Welten SM, Bastiaansen AJ, de Jong RC, de Vries MR, Peters EA, Boonstra MC, Sheikh SP, La Monica N, Kandimalla ER, Quax PH, Nossent AY. Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 increases neovascularization and blood flow recovery after ischemia. Circ Res. 2014;115(8):696-708.

     Not in our library10.1161/circresaha.114.304747

591. 591.
     TLR4 accessory molecule RP105 (CD180) regulates monocyte-driven arteriogenesis in a murine hind limb ischemia model. · 2014

     Not checked
592. 592.

     Bastiaansen AJ, Ewing MM, de Boer HC, van der Pouw Kraan TC, de Vries MR, Peters EA, Welten SM, Arens R, Moore SM, Faber JE, Jukema JW, Hamming JF, Nossent AY, Quax PH. Lysine acetyltransferase PCAF is a key regulator of arteriogenesis. Arterioscler Thromb Vasc Biol. 2013;33(8):1902-1910.

     Not in our library10.1161/atvbaha.113.301579

593. 593.

     Kochi T, Imai Y, Takeda A, Watanabe Y, Mori S, Tachi M, Kodama T. Characterization of the arterial anatomy of the murine hindlimb: functional role in the design and understanding of ischemia models. PLoS ONE. 2013;8(12):e84047.

     Not in our library10.1371/journal.pone.0084047

594. 594.

     Thomas D, Thirumaran A, Mallard B, Chen X, Browne S, Wheatley AM, O’Brien T, Pandit A. Variability in endogenous perfusion recovery of immunocompromised mouse models of limb ischemia. Tissue Eng Part C Methods. 2016;22(4):370-381.

     Not in our library10.1089/ten.tec.2015.0441

595. 595.

     Nebuloni L, Kuhn GA, Vogel J, Muller R. A novel in vivo vascular imaging approach for hierarchical quantification of vasculature using contrast enhanced micro-computed tomography. PLoS ONE. 2014;9(1):e86562.

     Not in our library10.1371/journal.pone.0086562

596. 596.

     Hendrikx G, Vries MH, Bauwens M, De Saint-Hubert M, Wagenaar A, Guillaume J, Boonen L, Post MJ, Mottaghy FM. Comparison of LDPI to SPECT perfusion imaging using (99 m) Tc-sestamibi and (99 m)Tc-pyrophosphate in a murine ischemic hind limb model of neovascularization. EJNMMI Res. 2016;6(1):44.

     Not in our library10.1186/s13550-016-0199-2

597. 597.

     Yang Y, Tang G, Yan J, Park B, Hoffman A, Tie G, Wang R, Messina LM. Cellular and molecular mechanism regulating blood flow recovery in acute versus gradual femoral artery occlusion are distinct in the mouse. J Vasc Surg. 2008;48(6):1546-1558.

     Not in our library10.1016/j.jvs.2008.07.063

598. 598.

     Chalothorn D, Faber JE. Strain-dependent variation in collateral circulatory function in mouse hindlimb. Physiol Genom. 2010;42(3):469-479.

     Not in our library10.1152/physiolgenomics.00070.2010

599. 599.

     Shireman PK, Quinones MP. Differential necrosis despite similar perfusion in mouse strains after ischemia. J Surg Res. 2005;129(2):242-250.

     Not in our library10.1016/j.jss.2005.06.013

600. 600.

     Helisch A, Wagner S, Khan N, Drinane M, Wolfram S, Heil M, Ziegelhoeffer T, Brandt U, Pearlman JD, Swartz HM, Schaper W. Impact of mouse strain differences in innate hindlimb collateral vasculature. Arterioscler Thromb Vasc Biol. 2006;26(3):520-526.

     Not in our library10.1161/01.atv.0000202677.55012.a0

601. 601.

     Dokun AO, Chen L, Okutsu M, Farber CR, Hazarika S, Jones WS, Craig D, Marchuk DA, Lye RJ, Shah SH, Annex BH. ADAM12: a genetic modifier of preclinical peripheral arterial disease. Am J Physiol Heart Circ Physiol. 2015;309(5):H790-H803.

     Not in our library10.1152/ajpheart.00803.2014

602. 602.

     Dokun AO, Keum S, Hazarika S, Li Y, Lamonte GM, Wheeler F, Marchuk DA, Annex BH. A quantitative trait locus (LSq-1) on mouse chromosome 7 is linked to the absence of tissue loss after surgical hindlimb ischemia. Circulation. 2008;117(9):1207-1215.

     Not in our library10.1161/circulationaha.107.736447

603. 603.

     Lucitti JL, Sealock R, Buckley BK, Zhang H, Xiao L, Dudley AC, Faber JE. Variants of rab GTPase-effector binding protein-2 Cause variation in the collateral circulation and severity of stroke. Stroke. 2016;47(12):3022-3031.

     Not in our library10.1161/strokeaha.116.014160

604. 604.

     Sealock R, Zhang H, Lucitti JL, Moore SM, Faber JE. Congenic fine-mapping identifies a major causal locus for variation in the native collateral circulation and ischemic injury in brain and lower extremity. Circ Res. 2014;114(4):660-671.

     Not in our library10.1161/circresaha.114.302931

605. 605.

     Nossent AY, Bastiaansen AJ, Peters EA, de Vries MR, Aref Z, Welten SM, de Jager SC, van der Pouw Kraan TC, Quax PH. CCR7-CCL19/CCL21 axis is essential for effective arteriogenesis in a murine model of hindlimb ischemia. J Am Heart Assoc. 2017.

     Not in our library10.1161/jaha.116.005281

606. 606.

     Arras M, Ito WD, Scholz D, Winkler B, Schaper J, Schaper W. Monocyte activation in angiogenesis and collateral growth in the rabbit hindlimb. J Clin Invest. 1998;101(1):40-50.

     Not in our library10.1172/jci119877

607. 607.

     Monaco C. Innate immunity meets arteriogenesis: the versatility of toll-like receptors. J Mol Cell Cardiol. 2011;50(1):9-12.

     Not in our library10.1016/j.yjmcc.2010.10.015

608. 608.

     Silvestre JS, Smadja DM, Levy BI. Postischemic revascularization: from cellular and molecular mechanisms to clinical applications. Physiol Rev. 2013;93(4):1743-1802.

     Not in our library10.1152/physrev.00006.2013

609. 609.

     van der Bogt KE, Hellingman AA, Lijkwan MA, Bos EJ, de Vries MR, van Rappard JR, Fischbein MP, Quax PH, Robbins RC, Hamming JF, Wu JC. Molecular imaging of bone marrow mononuclear cell survival and homing in murine peripheral artery disease. JACC Cardiovasc Imaging. 2012;5(1):46-55.

     Not in our library10.1016/j.jcmg.2011.07.011

610. 610.

     Caporali A, Meloni M, Vollenkle C, Bonci D, Sala-Newby GB, Addis R, Spinetti G, Losa S, Masson R, Baker AH, Agami R, le Sage C, Condorelli G, Madeddu P, Martelli F, Emanueli C. Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia. Circulation. 2011;123(3):282-291.

     Not in our library10.1161/circulationaha.110.952325

611. 611.

     van Weel V, de Vries M, Voshol PJ, Verloop RE, Eilers PH, van Hinsbergh VW, van Bockel JH, Quax PH. Hypercholesterolemia reduces collateral artery growth more dominantly than hyperglycemia or insulin resistance in mice. Arterioscler Thromb Vasc Biol. 2006;26(6):1383-1390.

     Not in our library10.1161/01.atv.0000219234.78165.85

612. 612.

     Epstein SE, Stabile E, Kinnaird T, Lee CW, Clavijo L, Burnett MS. Janus phenomenon: the interrelated tradeoffs inherent in therapies designed to enhance collateral formation and those designed to inhibit atherogenesis. Circulation. 2004;109(23):2826-2831.

     Not in our library10.1161/01.cir.0000132468.82942.f5

613. 613.

     Sheu JJ, Chua S, Sun CK, Chang LT, Yen CH, Wu CJ, Fu M, Yip HK. Intra-coronary administration of cyclosporine limits infarct size, attenuates remodeling and preserves left ventricular function in porcine acute anterior infarction. Int J Cardiol. 2011;147(1):79-87.

     Not in our library10.1016/j.ijcard.2009.08.008

614. 614.

     Gotberg M, van der Pals J, Olivecrona GK, Gotberg M, Koul S, Erlinge D. Mild hypothermia reduces acute mortality and improves hemodynamic outcome in a cardiogenic shock pig model. Resuscitation. 2010;81(9):1190-1196.

     Not in our library10.1016/j.resuscitation.2010.04.033

615. 615.

     Kim W, Jeong MH, Sim DS, Hong YJ, Song HC, Park JT, Ahn YK. A porcine model of ischemic heart failure produced by intracoronary injection of ethyl alcohol. Heart Vessels. 2011;26(3):342-348.

     Not in our library10.1007/s00380-010-0022-3

616. 616.

     Lahteenvuo JE, Lahteenvuo MT, Kivela A, Rosenlew C, Falkevall A, Klar J, Heikura T, Rissanen TT, Vahakangas E, Korpisalo P, Enholm B, Carmeliet P, Alitalo K, Eriksson U, Yla-Herttuala S. Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1- and neuropilin receptor-1-dependent mechanisms. Circulation. 2009;119(6):845-856.

     Not in our library10.1161/circulationaha.108.816454

617. 617.

     Yla-Herttuala S, Bridges C, Katz MG, Korpisalo P. Angiogenic gene therapy in cardiovascular diseases: dream or vision? Eur Heart J. 2017;38(18):1365-1371.

     Not in our library10.1093/eurheartj/ehw547

618. 618.

     Roth DM, Maruoka Y, Rogers J, White FC, Longhurst JC, Bloor CM. Development of coronary collateral circulation in left circumflex Ameroid-occluded swine myocardium. Am J Physiol. 1987;253(5 Pt 2):H1279-H1288.

     Not in our library10.1152/ajpheart.1987.253.5.h1279

619. 619.

     Staab ME, Srivatsa SS, Lerman A, Sangiorgi G, Jeong MH, Edwards WD, Holmes DR, Schwartz RS. Arterial remodeling after experimental percutaneous injury is highly dependent on adventitial injury and histopathology. Int J Cardiol. 1997;58(1):31-40.

     Not in our library10.1016/s0167-5273(96)02844-6

620. 620.

     Song W, Lee J, Kim H, Shin J, Oh D, Tio F, Wong SC, Hong MK. A new percutaneous porcine coronary model of chronic total occlusion. J Invasive Cardiol. 2005;17(9):452-454.

     Not in our library

621. 621.

     Dymarkowski S, Szilard M, Maes A, Liu XS, Huang YM, Verbeken E, Mortelmans L, Bogaert J, De Scheerder I. Assessment of myocardial viability in a porcine model of chronic coronary artery stenosis with dual dose dobutamine magnetic resonance imaging. Int J Cardiovasc Imaging. 2003;19(1):63-72.

     Not in our library10.1023/a:1021781205016

622. 622.

     von Degenfeld G, Raake P, Kupatt C, Lebherz C, Hinkel R, Gildehaus FJ, Munzing W, Kranz A, Waltenberger J, Simoes M, Schwaiger M, Thein E, Boekstegers P. Selective pressure-regulated retroinfusion of fibroblast growth factor-2 into the coronary vein enhances regional myocardial blood flow and function in pigs with chronic myocardial ischemia. J Am Coll Cardiol. 2003;42(6):1120-1128.

     Not in our library10.1016/s0735-1097(03)00915-x

623. 623.

     Rissanen TT, Nurro J, Halonen PJ, Tarkia M, Saraste A, Rannankari M, Honkonen K, Pietila M, Leppanen O, Kuivanen A, Knuuti J, Yla-Herttuala S. The bottleneck stent model for chronic myocardial ischemia and heart failure in pigs. Am J Physiol Heart Circ Physiol. 2013;305(9):H1297-H1308.

     Not in our library10.1152/ajpheart.00561.2013

624. 624.

     Boulate D, Arthur Ataam J, Connolly AJ, Giraldeau G, Amsallem M, Decante B, Lamrani L, Fadel E, Dorfmuller P, Perros F, Haddad F, Mercier O. Early development of right ventricular ischemic lesions in a novel large animal model of acute right heart failure in chronic thromboembolic pulmonary hypertension. J Card Fail. 2017;23(12):876-886.

     Not in our library10.1016/j.cardfail.2017.08.447

625. 625.

     Wisenbaugh T, Allen P, Gt C, Holzgrefe H, Beller G, Carabello B. Contractile function, myosin ATPase activity and isozymes in the hypertrophied pig left ventricle after a chronic progressive pressure overload. Circ Res. 1983;53(3):332-341.

     Not in our library10.1161/01.res.53.3.332

626. 626.

     Ahmet I, Sawa Y, Iwata K, Matsuda H. Gene transfection of hepatocyte growth factor attenuates cardiac remodeling in the canine heart: a novel gene therapy for cardiomyopathy. J Thorac Cardiovasc Surg. 2002;124(5):957-963.

     Not in our library10.1067/mtc.2002.126655

627. 627.

     Wakelin SJ, Sabroe I, Gregory CD, Poxton IR, Forsythe JL, Garden OJ, Howie SE. “Dirty little secrets”—endotoxin contamination of recombinant proteins. Immunol Lett. 2006;106(1):1-7.

     Not in our library10.1016/j.imlet.2006.04.007

628. 628.

     Gorbet MB, Sefton MV. Endotoxin: the uninvited guest. Biomaterials. 2005;26(34):6811-6817.

     Not in our library10.1016/j.biomaterials.2005.04.063

629. 629.

     Magalhaes PO, Lopes AM, Mazzola PG, Rangel-Yagui C, Penna TC, Pessoa A. Methods of endotoxin removal from biological preparations: a review. J Pharm Pharm Sci. 2007;10(3):388-404.

     Not in our library

630. 630.

     Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, Ricciardi-Castagnoli P, Layton B, Beutler B. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 1998;282(5396):2085-2088.

     Not in our library10.1126/science.282.5396.2085

631. 631.

     Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol. 2001;1(2):135-145.

     Not in our library10.1038/35100529

632. 632.

     Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol. 2004;4(7):499-511.

     Not in our library10.1038/nri1391

633. 633.

     Arditi M, Zhou J, Dorio R, Rong GW, Goyert SM, Kim KS. Endotoxin-mediated endothelial cell injury and activation: role of soluble CD14. Infect Immun. 1993;61(8):3149-3156.

     Not in our library10.1128/iai.61.8.3149-3156.1993

634. 634.

     Unger RE, Peters K, Sartoris A, Freese C, Kirkpatrick CJ. Human endothelial cell-based assay for endotoxin as sensitive as the conventional limulus amebocyte lysate assay. Biomaterials. 2014;35(10):3180-3187.

     Not in our library10.1016/j.biomaterials.2013.12.059

635. 635.

     Mattsby-Baltzer I, Jakobsson A, Sorbo J, Norrby K. Endotoxin is angiogenic. Int J Exp Pathol. 1994;75(3):191-196.

     Not in our library

636. 636.

     Harmey JH, Bucana CD, Lu W, Byrne AM, McDonnell S, Lynch C, Bouchier-Hayes D, Dong Z. Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. Int J Cancer. 2002;101(5):415-422.

     Not in our library10.1002/ijc.10632

637. 637.

     Lundin JI, Checkoway H. Endotoxin and cancer. Environ Health Perspect. 2009;117(9):1344-1350.

     Not in our library10.1289/ehp.0800439

638. 638.

     Haricharan S, Brown P. TLR4 has a TP53-dependent dual role in regulating breast cancer cell growth. Proc Natl Acad Sci USA. 2015;112(25):E3216-E3225.

     Not in our library10.1073/pnas.1420811112

639. 639.

     Skobe M, Rockwell P, Goldstein N, Vosseler S, Fusenig NE. Halting angiogenesis suppresses carcinoma cell invasion. Nat Med. 1997;3(11):1222-1227.

     Not in our library10.1038/nm1197-1222

640. 640.

     Singh M, Couto SS, Forrest WF, Lima A, Cheng JH, Molina R, Long JE, Hamilton P, McNutt A, Kasman I, Nannini MA, Reslan HB, Cao TC, Ho CC, Barck KH, Carano RA, Foreman O, Eastham-Anderson J, Jubb AM, Ferrara N, Johnson L. Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models. J Pathol. 2012;227(4):417-430.

     Not in our library10.1002/path.4053

641. 641.

     Prewett M, Huber J, Li Y, Santiago A, O’Connor W, King K, Overholser J, Hooper A, Pytowski B, Witte L, Bohlen P, Hicklin DJ. Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis. Cancer Res. 1999;59:5209-5218.

     Not in our library

642. 642.

     Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Res. 2003;13(10):2265-2270.

     Not in our library10.1101/gr.1293003

643. 643.

     LeCouter J, Kowalski J, Foster J, Hass P, Zhang Z, Dillard-Telm L, Frantz G, Rangell L, DeGuzman L, Keller G-A, Peale F, Gurney A, Hillan KJ, Ferrara N. Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature. 2001;412:877-884.

     Not in our library10.1038/35091000

644. 644.

     Eswarappa SM, Potdar AA, Koch WJ, Fan Y, Vasu K, Lindner D, Willard B, Graham LM, DiCorleto PE, Fox PL. Programmed translational readthrough generates antiangiogenic VEGF-Ax. Cell. 2014;157(7):1605-1618.

     Not in our library10.1016/j.cell.2014.04.033

645. 645.

     Xin H, Zhong C, Nudleman E, Ferrara N. Evidence for pro-angiogenic functions of VEGF-Ax. Cell. 2016;167(1):275-284.

     Not in our library10.1016/j.cell.2016.08.054

646. 646.

     Lopez XM, Debeir O, Maris C, Rorive S, Roland I, Saerens M, Salmon I, Decaestecker C. Clustering methods applied in the detection of Ki67 hot-spots in whole tumor slide images: an efficient way to characterize heterogeneous tissue-based biomarkers. Cytom A. 2012;81(9):765-775.

     Not in our library10.1002/cyto.a.22085

647. 647.

     Hlushchuk R, Barré S, Djonov V. Morphological aspects of tumor angiogenesis. Methods Mol Biol. 2016;1464:13-24.

     Not in our library10.1007/978-1-4939-3999-2_2

648. 648.

     Hlushchuk R, Bronnimann D, Correa Shokiche C, Schaad L, Triet R, Jazwinska A, Tschanz SA, Djonov V. Zebrafish Caudal Fin angiogenesis assay-advanced quantitative assessment including 3-way correlative microscopy. PLoS ONE. 2016;11(3):e0149281.

     Not in our library10.1371/journal.pone.0149281

649. 649.

     Yu JA, Castranova D, Pham VN, Weinstein BM. Single-cell analysis of endothelial morphogenesis in vivo. Development. 2015;142(17):2951-2961.

     Not in our library10.1242/dev.123174

650. 650.

     Fujita M, Cha YR, Pham VN, Sakurai A, Roman BL, Gutkind JS, Weinstein BM. Assembly and patterning of the vascular network of the vertebrate hindbrain. Development. 2011;138(9):1705-1715.

     Not in our library10.1242/dev.058776

651. 651.

     Isogai S, Lawson ND, Torrealday S, Horiguchi M, Weinstein BM. Angiogenic network formation in the developing vertebrate trunk. Development. 2003;130(21):5281-5290.

     Not in our library10.1242/dev.00733

652. 652.

     Ribatti D, Bertossi M, Nico B, Vacca A, Ria R, Riva A, Roncali L, Presta M. Role of basic fibroblast growth factor in the formation of the capillary plexus in the chick embryo chorioallantoic membrane. An in situ hybridization, immunohistochemical and ultrastructural study. J Submicrosc Cytol Pathol. 1998;30(1):127-136.

     Not in our library

653. 653.

     Ribatti D, Nico B, Pezzolo A, Vacca A, Meazza R, Cinti R, Carlini B, Parodi F, Pistoia V, Corrias MV. Angiogenesis in a human neuroblastoma xenograft model: mechanisms and inhibition by tumour-derived interferon-gamma. Br J Cancer. 2006;94(12):1845-1852.

     Not in our library10.1038/sj.bjc.6603186

654. 654.

     Nurro J, Halonen PJ, Kuivanen A, Tarkia M, Saraste A, Honkonen K, Lahteenvuo J, Rissanen TT, Knuuti J, Yla-Herttuala S. AdVEGF-B186 and AdVEGF-DDeltaNDeltaC induce angiogenesis and increase perfusion in porcine myocardium. Heart. 2016;102(21):1716-1720.

     Not in our library10.1136/heartjnl-2016-309373

655. 655.

     Ausprunk DH, Knighton DR, Folkman J. Differentiation of vascular endothelium in the chick chorioallantois: a structural and autoradiographic study. Dev Biol. 1974;38(2):237-248.

     Not in our library10.1016/0012-1606(74)90004-9

656. 656.

     Lei Y, Rahim M, Ng Q, Segura T. Hyaluronic acid and fibrin hydrogels with concentrated DNA/PEI polyplexes for local gene delivery. J Control Release. 2011;153(3):255-261.

     Not in our library10.1016/j.jconrel.2011.01.028

657. 657.

     Forough R, Wang X, Martinez-Lemus LA, Thomas D, Sun Z, Motamed K, Parker JL, Meininger GA. Cell-based and direct gene transfer-induced angiogenesis via a secreted chimeric fibroblast growth factor-1 (sp-FGF-1) in the chick chorioallantoic membrane (CAM). Angiogenesis. 2003;6(1):47-54.

     Not in our library10.1023/a:1025857229064

658. 658.

     Javerzat S, Franco M, Herbert J, Platonova N, Peille AL, Pantesco V, De Vos J, Assou S, Bicknell R, Bikfalvi A, Hagedorn M. Correlating global gene regulation to angiogenesis in the developing chick extra-embryonic vascular system. PLoS ONE. 2009;4(11):e7856.

     Not in our library10.1371/journal.pone.0007856

659. 659.

     Cavill R, Sidhu JK, Kilarski W, Javerzat S, Hagedorn M, Ebbels TM, Bikfalvi A, Keun HC. A combined metabonomic and transcriptomic approach to investigate metabolism during development in the chick chorioallantoic membrane. J Proteome Res. 2010;9(6):3126-3134.

     Not in our library10.1021/pr100033t

660. 660.

     Soulet F, Kilarski WW, Antczak P, Herbert J, Bicknell R, Falciani F, Bikfalvi A. Gene signatures in wound tissue as evidenced by molecular profiling in the chick embryo model. BMC Genom. 2010;11:495.

     Not in our library10.1186/1471-2164-11-495

661. 661.

     Parsons-Wingerter P, McKay TL, Leontiev D, Vickerman MB, Condrich TK, Dicorleto PE. Lymphangiogenesis by blind-ended vessel sprouting is concurrent with hemangiogenesis by vascular splitting. Anat Rec A Discov Mol Cell Evol Biol. 2006;288(3):233-247.

     Not in our library10.1002/ar.a.20309

662. 662.

     Papoutsi M, Sleeman JP, Wilting J. Interaction of rat tumor cells with blood vessels and lymphatics of the avian chorioallantoic membrane. Microsc Res Tech. 2001;55(2):100-107.

     Not in our library10.1002/jemt.1161

663. 663.

     Wilting J, Neeff H, Christ B. Embryonic lymphangiogenesis. Cell Tissue Res. 1999;297(1):1-11.

     Not in our library10.1007/s004410051328

664. 664.

     Abe C, Uto Y, Nakae T, Shinmoto Y, Sano K, Nakata H, Teraoka M, Endo Y, Maezawa H, Masunaga S, Nakata E, Hori H. Evaluation of the in vivo radiosensitizing activity of etanidazole using tumor-bearing chick embryo. J Radiat Res. 2011;52(2):208-214.

     Not in our library10.1269/jrr.10122

665. 665.

     Kardamakis D, Hadjimichael C, Ginopoulos P, Papaioannou S. Effects of paclitaxel in combination with ionizing radiation on angiogenesis in the chick embryo chorioallantoic membrane. A radiobiological study. Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft [et al]. 2004;180(3):152-156.

     Not in our library10.1007/s00066-004-1140-6

666. 666.

     Kleibeuker EA, Ten Hooven MA, Castricum KC, Honeywell R, Griffioen AW, Verheul HM, Slotman BJ, Thijssen VL. Optimal treatment scheduling of ionizing radiation and sunitinib improves the antitumor activity and allows dose reduction. Cancer Med. 2015;4(7):1003-1015.

     Not in our library10.1002/cam4.441

667. 667.

     Bouchet A, Serduc R, Laissue JA, Djonov V. Effects of microbeam radiation therapy on normal and tumoral blood vessels. Phys Med. 2015;31(6):634-641.

     Not in our library10.1016/j.ejmp.2015.04.014

668. 668.

     Nowak-Sliwinska P, van Beijnum JR, van Berkel M, van den Bergh H, Griffioen AW. Vascular regrowth following photodynamic therapy in the chicken embryo chorioallantoic membrane. Angiogenesis. 2010;13(4):281-292.

     Not in our library10.1007/s10456-010-9185-x

669. 669.

     Nowak-Sliwinska P, Weiss A, Beijnum JR, Wong TJ, Ballini JP, Lovisa B, van den Bergh H, Griffioen AW. Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion. J Cell Mol Med. 2012;16(7):1553-1562.

     Not in our library10.1111/j.1582-4934.2011.01440.x

670. 670.

     Lange N, Ballini JP, Wagnieres G, van den Bergh H. A new drug-screening procedure for photosensitizing agents used in photodynamic therapy for CNV. Invest Ophthalmol Vis Sci. 2001;42(1):38-46.

     Not in our library

671. 671.

     Samkoe KS, Clancy AA, Karotki A, Wilson BC, Cramb DT. Complete blood vessel occlusion in the chick chorioallantoic membrane using two-photon excitation photodynamic therapy: implications for treatment of wet age-related macular degeneration. J Biomed Opt. 2007;12(3):034025.

     Not in our library10.1117/1.2750663

672. 672.

     Piffaretti F, Novello AM, Kumar RS, Forte E, Paulou C, Nowak-Sliwinska P, van den Bergh H, Wagnieres G. Real-time, in vivo measurement of tissular pO2 through the delayed fluorescence of endogenous protoporphyrin IX during photodynamic therapy. J Biomed Opt. 2012;17(11):115007.

     Not in our library10.1117/1.jbo.17.11.115007

673. 673.

     Chiba M, Ichikawa Y, Kamiya M, Komatsu T, Ueno T, Hanaoka K, Nagano T, Lange N, Urano Y. An activatable photosensitizer targeted to gamma-glutamyltranspeptidase. Angew Chem. 2017;56(35):10418-10422.

     Not in our library10.1002/anie.201704793

674. 674.

     Kucinska M, Murias M, Nowak-Sliwinska P. Beyond mouse cancer models: three-dimensional human-relevant in vitro and non-mammalian in vivo models for photodynamic therapy. Mutat Res. 2017;773:242-262.

     Not in our library10.1016/j.mrrev.2016.09.002

675. 675.

     Debefve E, Pegaz B, van den Bergh H, Wagnieres G, Lange N, Ballini JP. Video monitoring of neovessel occlusion induced by photodynamic therapy with verteporfin (Visudyne), in the CAM model. Angiogenesis. 2008;11(3):235-243.

     Not in our library10.1007/s10456-008-9106-4

676. 676.

     Samkoe KS, Cramb DT. Application of an ex ovo chicken chorioallantoic membrane model for two-photon excitation photodynamic therapy of age-related macular degeneration. J Biomed Opt. 2003;8(3):410-417.

     Not in our library10.1117/1.1577117

677. 677.

     Dagg CP, Karnofsky DA, Roddy J. Growth of transplantable human tumors in the chick embryo and hatched chick. Can Res. 1956;16(7):589-594.

     Not in our library

678. 678.

     Fergelot P, Bernhard JC, Soulet F, Kilarski WW, Leon C, Courtois N, Deminiere C, Herbert JM, Antczak P, Falciani F, Rioux-Leclercq N, Patard JJ, Ferriere JM, Ravaud A, Hagedorn M, Bikfalvi A. The experimental renal cell carcinoma model in the chick embryo. Angiogenesis. 2013;16(1):181-194.

     Not in our library10.1007/s10456-012-9311-z

679. 679.

     Wilson SM, Chambers AF. Experimental metastasis assays in the chick embryo. Curr Protoc Cell Biol. 2004.

     Not in our library10.1002/0471143030.cb1906s21

680. 680.

     Deryugina EI, Quigley JP. Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis. Histochem Cell Biol. 2008;130(6):1119-1130.

     Not in our library10.1007/s00418-008-0536-2

681. 681.

     Cimpean AM, Ribatti D, Raica M. The chick embryo chorioallantoic membrane as a model to study tumor metastasis. Angiogenesis. 2008;11(4):311-319.

     Not in our library10.1007/s10456-008-9117-1

682. 682.
     MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours · 2017

     Not checked
683. 683.

     Huntosova V, Gay S, Nowak-Sliwinska P, Rajendran SK, Zell-weger M, van den Bergh H, Wagnieres G. In vivo measurement of tissue oxygenation by time-resolved luminescence spectroscopy: advantageous properties of dichlorotris(1, 10-phenanthroline)-ruthenium(II) hydrate. J Biomed Opt. 2014;19(7):77004.

     Not in our library10.1117/1.jbo.19.7.077004

684. 684.

     van Wijk XM, Thijssen VL, Lawrence R, van den Broek SA, Dona M, Naidu N, Oosterhof A, van de Westerlo EM, Kusters LJ, Khaled Y, Jokela TA, Nowak-Sliwinska P, Kremer H, Stringer SE, Griffioen AW, van Wijk E, van Delft FL, van Kuppevelt TH. Interfering with UDP-GlcNAc metabolism and heparan sulfate expression using a sugar analogue reduces angiogenesis. ACS Chem Biol. 2013;8(10):2331-2338.

     Not in our library10.1021/cb4004332

685. 685.

     van Beijnum JR, Thijssen VL, Lappchen T, Wong TJ, Verel I, Engbersen M, Schulkens IA, Rossin R, Grull H, Griffioen AW, Nowak-Sliwinska P. A key role for galectin-1 in sprouting angiogenesis revealed by novel rationally designed antibodies. Int J Cancer. 2016;139(4):824-835.

     Not in our library10.1002/ijc.30131

686. 686.

     Berndsen RH, Weiss A, Abdul UK, Wong TJ, Meraldi P, Griffioen AW, Dyson PJ, Nowak-Sliwinska P. Combination of ruthenium(II)-arene complex [Ru(eta(6)-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity. Sci Rep. 2017;7:43005.

     Not in our library10.1038/srep43005

687. 687.

     Nowak-Sliwinska P, Clavel CM, Paunescu E, te Winkel MT, Griffioen AW, Dyson PJ. Antiangiogenic and anticancer properties of bifunctional ruthenium(II)-p-cymene complexes: influence of pendant perfluorous chains. Mol Pharm. 2015;12(8):3089-3096.

     Not in our library10.1021/acs.molpharmaceut.5b00417

688. 688.

     Stibal D, Therrien B, Suss-Fink G, Nowak-Sliwinska P, Dyson PJ, Cermakova E, Rezacova M, Tomsik P. Chlorambucil conjugates of dinuclear p-cymene ruthenium trithiolato complexes: synthesis, characterization and cytotoxicity study in vitro and in vivo. J Biol Inorgan Chem. 2016;21(4):443-452.

     Not in our library10.1007/s00775-016-1353-z

689. 689.

     Clavel CM, Paunescu E, Nowak-Sliwinska P, Griffioen AW, Scopelliti R, Dyson PJ. Modulating the anticancer activity of ruthenium(II)-arene complexes. J Med Chem. 2015;58(8):3356-3365.

     Not in our library10.1021/jm501655t

690. 690.

     Nazarov AA, Baquie M, Nowak-Sliwinska P, Zava O, van Beijnum JR, Groessl M, Chisholm DM, Ahmadi Z, McIndoe JS, Griffioen AW, van den Bergh H, Dyson PJ. Synthesis and characterization of a new class of anti-angiogenic agents based on ruthenium clusters. Sci Rep. 2013;3:1485.

     Not in our library10.1038/srep01485

691. 691.

     Paunescu E, Nowak-Sliwinska P, Clavel CM, Scopelliti R, Griffioen AW, Dyson PJ. Anticancer organometallic osmium(II)-p-cymene complexes. ChemMedChem. 2015;10(9):1539-1547.

     Not in our library10.1002/cmdc.201500221

692. 692.

     Deryugina EI, Quigley JP. Chapter 2. Chick embryo chorioallantoic membrane models to quantify angiogenesis induced by inflammatory and tumor cells or purified effector molecules. Methods Enzymol. 2008;444:21-41.

     Not in our library10.1016/s0076-6879(08)02802-4

693. 693.

     Reuwer AQ, Nowak-Sliwinska P, Mans LA, van der Loos CM, von der Thusen JH, Twickler MT, Spek CA, Goffin V, Griffioen AW, Borensztajn KS. Functional consequences of prol-actin signalling in endothelial cells: a potential link with angiogenesis in pathophysiology? J Cell Mol Med. 2012;16(9):2035-2048.

     Not in our library10.1111/j.1582-4934.2011.01499.x

694. 694.

     Comsa S, Ceausu RA, Popescu R, Cimpean AM, Raica M. The human mesenchymal stem cells and the chick embryo chorioallantoic membrane: the key and the lock in revealing vasculogenesis. In vivo. 2017;31(6):1139-1144.

     Not in our library10.21873/invivo.11180

695. 695.

     Edwards SS, Zavala G, Prieto CP, Elliott M, Martinez S, Egana JT, Bono MR, Palma V. Functional analysis reveals angiogenic potential of human mesenchymal stem cells from Wharton’s jelly in dermal regeneration. Angiogenesis. 2014;17(4):851-866.

     Not in our library10.1007/s10456-014-9432-7

696. 696.

     Navarro-Requena C, Weaver JD, Clark AY, Clift DA, Perez-Amodio S, Castano O, Zhou DW, Garcia AJ, Engel E. PEG hydrogel containing calcium-releasing particles and mesenchymal stromal cells promote vessel maturation. Acta Biomater. 2018;67:53-65.

     Not in our library10.1016/j.actbio.2017.12.009

697. 697.

     Pisati F, Belicchi M, Acerbi F, Marchesi C, Giussani C, Gavina M, Javerzat S, Hagedorn M, Carrabba G, Lucini V, Gaini SM, Bresolin N, Bello L, Bikfalvi A, Torrente Y. Effect of human skin-derived stem cells on vessel architecture, tumor growth, and tumor invasion in brain tumor animal models. Can Res. 2007;67(7):3054-3063.

     Not in our library10.1158/0008-5472.can-06-1384

698. 698.

     Swadi R, Mather G, Pizer BL, Losty PD, See V, Moss D. Optimising the chick chorioallantoic membrane xenograft model of neuroblastoma for drug delivery. BMC Cancer. 2018;18(1):28.

     Not in our library10.1186/s12885-017-3978-x

699. 699.

     Vargas A, Lange N, Arvinte T, Cerny R, Gurny R, Delie F. Toward the understanding of the photodynamic activity of m-THPP encapsulated in PLGA nanoparticles: correlation between nanoparticle properties and in vivo activity. J Drug Target. 2009;17(8):599-609.

     Not in our library10.1080/10611860903118914

700. 700.

     Pedrosa P, Heuer-Jungemann A, Kanaras AG, Fernandes AR, Baptista PV. Potentiating angiogenesis arrest in vivo via laser irradiation of peptide functionalised gold nanoparticles. J Nanobiotechnol. 2017;15(1):85.

     Not in our library10.1186/s12951-017-0321-2

701. 701.

     Sarsons CD, Tekrony A, Yaehne K, Childs S, Rinker KD, Cramb D. Testing nanoparticles for angiogenesis-related disease: charting the fastest route to the clinic. J Biomed Nanotechnol. 2014;10(9):1641-1676.

     Not in our library10.1166/jbn.2014.1931

702. 702.

     Vargas A, Zeisser-Labouebe M, Lange N, Gurny R, Delie F. The chick embryo and its chorioallantoic membrane (CAM) for the in vivo evaluation of drug delivery systems. Adv Drug Deliv Rev. 2007;59(11):1162-1176.

     Not in our library10.1016/j.addr.2007.04.019

703. 703.

     Borges J, Tegtmeier FT, Padron NT, Mueller MC, Lang EM, Stark GB. Chorioallantoic membrane angiogenesis model for tissue engineering: a new twist on a classic model. Tissue Eng. 2003;9(3):441-450.

     Not in our library10.1089/107632703322066624

704. 704.

     Laschke MW, Harder Y, Amon M, Martin I, Farhadi J, Ring A, Torio-Padron N, Schramm R, Rucker M, Junker D, Haufel JM, Carvalho C, Heberer M, Germann G, Vollmar B, Menger MD. Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes. Tissue Eng. 2006;12(8):2093-2104.

     Not in our library10.1089/ten.2006.12.2093

705. 705.

     Moreno-Jimenez I, Kanczler JM, Hulsart-Billstrom G, Inglis S, Oreffo ROC. The chorioallantoic membrane assay for biomaterial testing in tissue engineering: a short-term in vivo preclinical model. Tissue Eng Part C Methods. 2017;23(12):938-952.

     Not in our library10.1089/ten.tec.2017.0186

706. 706.

     Perugini V, Guildford AL, Silva-Correia J, Oliveira JM, Meikle ST, Reis RL, Santin M. Anti-angiogenic potential of VEGF blocker dendron loaded on to gellan gum hydrogels for tissue engineering applications. J Tissue Eng Regen Med. 2018;12(2):e669-e678.

     Not in our library10.1002/term.2340

707. 707.

     Chary SR, Jain RK. Direct measurement of interstitial convection and diffusion of albumin in normal and neoplastic tissues by fluorescence photobleaching. Proc Natl Acad Sci USA. 1989;86(14):5385-5389.

     Not in our library10.1073/pnas.86.14.5385

708. 708.

     Bruns OT, Bischof TS, Harris DK, Franke D, Shi Y, Riedemann L, Bartelt A, Jaworski FB, Carr JA, Rowlands CJ, Wilson MWB, Chen O, Wei H, Hwang GW, Montana DM, Coropceanu I, Achorn OB, Kloepper J, Heeren J, So PTC, Fukumura D, Jensen KF, Jain RK, Bawendi MG. Next-generation in vivo optical imaging with short-wave infrared quantum dots. 2017;1:0056.

     Not in our library10.1038/s41551-017-0056

709. 709.

     Gohongi T, Fukumura D, Boucher Y, Yun CO, Soff GA, Compton C, Todoroki T, Jain RK. Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor beta1. Nat Med. 1999;5(10):1203-1208.

     Not in our library10.1038/13524

710. 710.

     Padera TP, Kadambi A, di Tomaso E, Carreira CM, Brown EB, Boucher Y, Choi NC, Mathisen D, Wain J, Mark EJ, Munn LL, Jain RK. Lymphatic metastasis in the absence of functional intratumor lymphatics. Science. 2002;296(5574):1883-1886.

     Not in our library10.1126/science.1071420

711. 711.

     Ny A, Koch M, Schneider M, Neven E, Tong RT, Maity S, Fischer C, Plaisance S, Lambrechts D, Heligon C, Terclavers S, Ciesiolka M, Kalin R, Man WY, Senn I, Wyns S, Lupu F, Brandli A, Vleminckx K, Collen D, Dewerchin M, Conway EM, Moons L, Jain RK, Carmeliet P. A genetic Xenopus laevis tadpole model to study lymphangiogenesis. Nat Med. 2005;11(9):998-1004.

     Not in our library10.1038/nm1285

712. 712.

     Chen O, Riedemann L, Etoc F, Herrmann H, Coppey M, Barch M, Farrar CT, Zhao J, Bruns OT, Wei H, Guo P, Cui J, Jensen R, Chen Y, Harris DK, Cordero JM, Wang Z, Jasanoff A, Fukumura D, Reimer R, Dahan M, Jain RK, Bawendi MG. Magneto-fluorescent core-shell supernanoparticles. Nat Commun. 2014;5:5093.

     Not in our library10.1038/ncomms6093

713. 713.

     Au P, Tam J, Duda DG, Lin PC, Munn LL, Fukumura D, Jain RK. Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo. Am J Pathol. 2009;175(1):294-302.

     Not in our library10.2353/ajpath.2009.080887

714. 714.

     Izumi Y, Xu L, di Tomaso E, Fukumura D, Jain RK. Tumour biology: herceptin acts as an anti-angiogenic cocktail. Nature. 2002;416(6878):279-280.

     Not in our library10.1038/416279b

Cited by papers we hold 11

• Pathological angiogenesis: mechanisms and therapeutic strategies · 2023
  No notice
• Umbilical Cord Blood-Derived Exosomes From Very Preterm Infants With Bronchopulmonary Dysplasia Impaired Endothelial Angiogenesis: Roles of Exosomal MicroRNAs · 2021
  Not checked
• Anti-Angiogenic Therapy: Current Challenges and Future Perspectives · 2021
  No notice
• M2 Macrophage-Derived Exosomes Promote Angiogenesis and Growth of Pancreatic Ductal Adenocarcinoma by Targeting E2F2 · 2021
  No notice
• The role of long noncoding RNAs in ischaemic stroke · 2020
  Not checked
• The Importance of Mechanical Forces for in vitro Endothelial Cell Biology · 2020
  No notice
• Angiogenesis Analyzer for ImageJ — A comparative morphometric analysis of “Endothelial Tube Formation Assay” and “Fibrin Bead Assay” · 2020
  No notice
• The role of glycolysis and mitochondrial respiration in the formation and functioning of endothelial tip cells during angiogenesis · 2019
  No notice
• Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function · 2019
  No notice
• Tumor angiogenesis: causes, consequences, challenges and opportunities · 2019
  No notice
• Unraveling the Role of Angiogenesis in Cancer Ecosystems · 2018
  No notice

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