Fecal matter transplant from Ace2 overexpressing mice counteracts chronic hypoxia‐induced pulmonary hypertension

Abstract Recent evidence suggests pulmonary hypertension (PH), a disease of the pulmonary vasculature actually has multiorgan pathophysiology and perhaps etiology. Herein, we demonstrated that fecal matter transplantation from angiotensin‐converting enzyme 2 overexpressing mice counteracted the effects of chronic hypoxia to prevent pulmonary hypertension, neuroinflammation, and gut dysbiosis in wild type recipients.

Abstract licence: CC BY-NC

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