PET Imaging of CXCR4 Receptors in Cancer by a New Optimized Ligand

Abstract

CXCR4 Imaging: Based on a high-affinity CXCR4 ligand, an imaging agent for CXCR4-positive tumors was developed through structure–activity relationship studies. The best compound was evaluated in vivo and shown to have excellent properties as a positron emission tomography (PET) tracer.

Shown for reading. Its publisher allows quoting it, not republishing it.

References 29

1. 1.

   van't Veer LJ, Bernards R. Nature. 2008;452:564.

   Not in our library10.1038/nature06915

2. 2.

   Langer A. BMC Health Serv. Res. 2010;10:283.

   Not in our library10.1186/1472-6963-10-283

3. 3.

   Jiang Y, Wang M. Biomarkers Med. 2010;4:523.

   Not in our library10.2217/bmm.10.66

4. 4.

   Diamandis M, White NM, Yousef GM. Mol. Cancer Res. 2010;8:1175.

   Not in our library10.1158/1541-7786.mcr-10-0264

5. 5.

   Pysz MA, Gambhir SS, Willmann JK. Clin. Radiol. 2010;65:500.

   Not in our library10.1016/j.crad.2010.03.011

6. 6.

   Haubner R, Kuhnast B, Mang C, Weber WA, Kessler H, Wester HJ, Schwaiger M. Bioconjugate Chem. 2004;15:61.

   Not in our library10.1021/bc034170n

7. 7.

   Schottelius M, Laufer B, Kessler H, Wester HJ. Acc. Chem. Res. 2009;42:969.

   Not in our library10.1021/ar800243b

8. 8.

   Wester HJ, Herz M, Weber W, Heiss P, Senekowitsch-Schmidtke R, Schwaiger M, Stöcklin G. J. Nucl. Med. 1999;40:205.

   Not in our library

9. 9.

   Balkwill F. Nat. Rev. Cancer. 2004;4:540.

   Not in our library10.1038/nrc1388

10. 10.

    Masuda M, Nakashima H, Ueda T, Naba H, Ikoma R, Otaka A, Terakawa Y, Tamamura H, Ibuka T, Murakami T, Koyanagi Y, Waki M, Matsumoto A, Yamamoto N, Funakoshi S, Fujii N. Biochem. Biophys. Res. Commun. 1992;189:845.

    Not in our library10.1016/0006-291x(92)92280-b

11. 11.

    De Clercq E, Yamamoto N, Pauwels R, Balzarini J, Witvrouw M, De Vreese K, Debyser Z, Rosenwirth B, Peichl P, Datema R, Thornton D, Skerlj R, Gaul F, Padmanabhan S, Bridger G, Henson G, Abrams M. Antimicrob. Agents Chemother. 1994;38:668.

    Not in our library10.1128/aac.38.4.668

12. 12.

    Tamamura H, Arakaki R, Funakoshi H, Imai M, Otaka A, Ibuka T, Nakashima H, Murakami T, Waki M, Matsumoto A, Yamamoto N, Fujii N. Bioorg. Med. Chem. 1998;6:231.

    Not in our library10.1016/s0968-0896(97)10037-2

13. 13.

    Ichiyama K, Yokoyama-Kumakura S, Tanaka Y, Tanaka R, Hirose K, Bannai K, Edamatsu T, Yanaka M, Niitani Y, Miyano-Kurosaki N, Takaku H, Koyanagi Y, Yamamoto N. Proc. Natl. Acad. Sci. USA. 2003;100:4185.

    Not in our library10.1073/pnas.0630420100

14. 14.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

15. 15.

    Tamamura H, Araki T, Ueda S, Wang ZX, Oishi S, Esaka A, Trent JO, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N. J. Med. Chem. 2005;48:3280.

    Not in our library10.1021/jm050009h

16. 16.

    DeMarco SJ, Henze H, Lederer A, Moehle K, Mukherjee R, Romagnoli B, Robinson JA, Brianza F, Gombert FO, Lociuro S, Ludin C, Vrijbloed JW, Zumbrunn J, Obrecht JP, Obrecht D, Brondani V, Hamy F, Klimkait T. Bioorg. Med. Chem. 2006;14:8396.

    Not in our library10.1016/j.bmc.2006.09.003

17. 17.

    Zhan WQ, Liang ZX, Zhu AZ, Kurtkaya S, Shim H, Snyder JP, Liotta DC. J. Med. Chem. 2007;50:5655.

    Not in our library10.1021/jm070679i

18. 18.

    Thoma G, Streiff MB, Kovarik J, Glickman F, Wagner T, Beerli C, Zerwes HG. J. Med. Chem. 2008;51:7915.

    Not in our library10.1021/jm801065q

19. 19.

    Hanaoka H, Mukai T, Tamamura H, Mori T, Ishino S, Ogawa K, Iida Y, Doi R, Fujii N, Saji H. Nucl. Med. Biol. 2006;33:489.

    Not in our library10.1016/j.nucmedbio.2006.01.006

20. 20.

    Nimmagadda S, Pullambhatla M, Pomper MG. J. Nucl. Med. 2009;50:1124.

    Not in our library10.2967/jnumed.108.061325

21. 21.

    Fujii N, Oishi S, Hiramatsu K, Araki T, Ueda S, Tamamura H, Otaka A, Kusano S, Terakubo S, Nakashima H, Broach JA, Trent JO, Wang ZX, Peiper SC. Angew. Chem. 2003;115:3373.

    Not in our library

22. 22.

    Ueda S, Oishi S, Wang ZX, Araki T, Tamamura H, Cluzeau J, Ohno H, Kusano S, Nakashima H, Trent JO, Peiper SC, Fujii N. J. Med. Chem. 2007;50:192.

    Not in our library10.1021/jm0607350

23. 23.

    Wang Z-x, Tamamura H, Frilot N, Broach J, Fujii N, Peiper SC, Neote K, Letts GL, Moser B. Chemokine Biology: Basic Research and Clinical Application, Vol. II: Pathophysiology of Chemokines. 2007;61.

    Not in our library

24. 24.

    Demmer O, Dijkgraaf I, Schottelius M, Wester HJ, Kessler H. Org. Lett. 2008;10:2015.

    Not in our library10.1021/ol800654n

25. 25.

    Demmer O, Koglin N, Wester HJ, Kessler H, Rolka K, Rekowski P, Silberring J. Peptides 2006: Proceedings of the 29th European Peptide Symposium, September 3–8, 2006; Gdańsk, Poland. 630.

    Not in our library

26. 26.

    Gerlach LO, Jakobsen JS, Jensen KP, Rosenkilde MR, Skerlj RT, Ryde U, Bridger GJ, Schwartz TW. Biochemistry. 2003;42:710.

    Not in our library10.1021/bi0264770

27. 27.

    Liu S, Edwards DS. Bioconjugate Chem. 2001;12:7.

    Not in our library10.1021/bc000070v

28. 28.

    Deshmukh MV, Voll G, Kuhlewein A, Macke H, Schmitt J, Kessler H, Gemmecker G. J. Med. Chem. 2005;48:1506.

    Not in our library10.1021/jm0496335

29. 29.

    De León-Rodriguez LM, Kovacs Z. Bioconjugate Chem. 2008;19:391.

    Not in our library10.1021/bc700328s

Cited by papers we hold 1

• In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma · 2015
  No notice

Reads

A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.