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Crizotinib‐associated renal cyst development may be associated with prolonged progression‐free survival in patients with ALK‐positive non‐small‐cell lung cancer: Case report and review of the literature

Nathaniel E. Wiest, Katherine S. Tzou, Matthew T. Olson and 6 more

Clinical Case Reports · 2021

doi:10.1002/ccr3.4278 (opens in a new tab)

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Abstract

Abstract Non‐small cell lung cancer patients with anaplastic lymphoma kinase or c‐ros oncogene 1 mutations who are treated with the tyrosine kinase inhibitor crizotinib rarely develop crizotinib‐associated renal cysts (CARCs). Here, we present a case report and review of the literature supporting the hypothesis that CARCs may correlate positively with progression‐free survival.

Abstract licence: CC BY-NC

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