Photoreversible Patterning of Biomolecules within Click‐Based Hydrogels

Abstract

Lighting the way: Biochemical cues have been reversibly patterned into hydrogels with full spatiotemporal control by using two photochemical reactions. The hydrogel is conjugated with a peptide by a thiol-ene photoaddition reaction that is initiated by visible light. Subsequent, selective photocleavage of an o-nitrobenzyl ether with UV light enables dynamic presentation of the peptide to cells with control in three dimensions.

Shown for reading. Its publisher allows quoting it, not republishing it.

References 23

1. 1.

   Peppas NA, Hilt JZ, Khademhosseini A, Langer R. Adv. Mater. 2006;18:1345.

   Not in our library

2. 2.

   Tibbitt MW, Anseth KS. Biotechnol. Bioeng. 2009;103:655.

   Not in our library10.1002/bit.22361

3. 3.

   Cushing MC, Anseth KS. Science. 2007;316:1133.

   Not in our library10.1126/science.1140171

4. 4.

   Lutolf MP, Gilbert PM, Blau HM. Nature. 2009;462:433.

   Not in our library10.1038/nature08602

5. 5.

   Khetan S, Burdick JA. Soft Matter. 2011;7:830.

   Not in our library

6. 6.

   Hahn MS, Miller JS, West JL. Adv. Mater. 2006;18:2679.

   Not in our library

7. 7.

   DeForest CA, Polizzotti BD, Anseth KS. Nat. Mater. 2009;8:659.

   Not in our library10.1038/nmat2473

8. 8.

   Aizawa Y, Wylie R, Shoichet M. Adv. Mater. 2010;22:4831.

   Not in our library10.1002/adma.201001855

9. 9.

   Leslie-Barbick JE, Shen C, Chen C, West JL. Tissue Eng. Part A. 2011;17:221.

   Not in our library10.1089/ten.tea.2010.0202

10. 10.

    Lee SH, Moon JJ, West JL. Biomaterials. 2008;29:2962.

    Not in our library10.1016/j.biomaterials.2008.04.004

11. 11.

    DeForest CA, Anseth KS. Nat. Chem. 2011;3:925.

    Not in our library10.1038/nchem.1174

12. 12.

    Hoyle CE, Bowman CN. Angew. Chem. 122;1584.

    Not in our library10.1002/anie.200903924

13. 13.

    Uygun M, Tasdelen MA, Yagci Y. Macromol. Chem. Phys. 2010;211:103.

    Not in our library

14. 14.

    Kloxin AM, Kasko AM, Salinas CN, Anseth KS. Science. 2009;324:59.

    Not in our library10.1126/science.1169494

15. 15.

    Holmes CP, Jones DG. J. Org. Chem. 1995;60:2318.

    Not in our library

16. 16.

    Vaultier M, Knouzi N, Carrié R. Tetrahedron Lett. 1983;24:763.

    Not in our library

17. 17.

    Sims EA, DeForest CA, Anseth KS. Tetrahedron Lett. 2011;52:1871.

    Not in our library10.1016/j.tetlet.2011.02.029

18. 18.

    Codelli JA, Baskin JM, Agard NJ, Berozzi CR. J. Am. Chem. Soc. 2008;130:11486.

    Not in our library10.1021/ja803086r

19. 19.

    DeForest CA, Sims EA, Anseth KS. Chem. Mater. 2010;22:4783.

    Not in our library10.1021/cm101391y

20. 20.

    Fairbanks BD, Schwartz MP, Halevi AE, Nuttelman CR, Bowman CN, Anseth KS. Adv. Mater. 2009;21:5005.

    Not in our library10.1002/adma.200901808

21. 21.

    Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 2002;1616.

    Not in our library

22. 22.

    Johnson PM, Reynolds TB, Stansbury JW, Bowman CN. Polymer. 2005;46:3300.

    Not in our library

23. 23.

    Bryant SJ, Nuttelman CR, Anseth KS. J. Biomater. Sci. Polym. Ed. 2000;11:439.

    Not in our library10.1163/156856200743805

Cited by papers we hold 5

• Engineered hydrogels for mechanobiology · 2022
  No notice
• Towards organoid culture without Matrigel · 2021
  No notice
• Design Challenges in Polymeric Scaffolds for Tissue Engineering · 2021
  No notice
• A Reversible and Repeatable Thiol–Ene Bioconjugation for Dynamic Patterning of Signaling Proteins in Hydrogels · 2018
  Not checked
• Microscale Architecture in Biomaterial Scaffolds for Spatial Control of Neural Cell Behavior · 2018
  Not checked

Reads

A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.